Age- and Sex-Specific Reference Intervals for Laboratory Parameters from Aging Trajectories in Healthy Beijing Adults (2010–2026)
This study establishes age- and sex-specific reference intervals for laboratory parameters in healthy Beijing adults by analyzing longitudinal data from 2010 to 2026, identifying key aging inflection points to demonstrate that uniform reference intervals systematically misclassify physiological aging—particularly in peri- and post-menopausal women—as pathology.