📄 medicine

Age- and Sex-Specific Reference Intervals for Laboratory Parameters from Aging Trajectories in Healthy Beijing Adults (2010–2026)

This study establishes age- and sex-specific reference intervals for laboratory parameters in healthy Beijing adults by analyzing longitudinal data from 2010 to 2026, identifying key aging inflection points to demonstrate that uniform reference intervals systematically misclassify physiological aging—particularly in peri- and post-menopausal women—as pathology.

Qi Liu, Jingjin Tao, He Wang, Chong Wang, Yuying Nie, Zhongxin Li, Zhongjun Shen, Xiangyi Xu, Huike Guo, Boxin Yang, Zhe (…)2026-10-09
📄 medicine

Using the WHO Checklist to Identify Domains for Institutionalizing Evidence-Informed Policy-Making in China: A Mapping Review

This mapping review of 168 records characterizes the current state of evidence-informed policy-making institutionalization in China, revealing that existing evidence is heavily concentrated in the Governance and Resources domains within the health and institutional sectors, while highlighting a critical need to strengthen cultural and leadership aspects to broaden institutionalization across other policy areas.

Zixuan Gan, Jinnan Zhang, Ruixin Li, Wenlu Cai, Xinyuan Zhang, Mukdarut Bangpan, Howard White, Xiuxia Li, Lufang Feng, Y (…)2026-10-09
📄 medicine

Pertussis vaccination of pregnant women: a mixed methods study investigating uptake and its associated factors (PREVACOQ-2.1)

This mixed-methods study conducted in Loire-Atlantique, France, found a high (79%) pertussis vaccination uptake among pregnant women two years after national recommendation, identifying primiparity, higher education, and influenza vaccination as key drivers while highlighting the need for better information to address remaining hesitancy.

Clarisse Le Guinio, Jean-François Huon, Olivier Grossi, Valérie Briend-Godet, Manon Bouteau, Maeva Lefebvre2026-10-09
📄 medicine

Baseline menopausal hormone therapy history and subsequent recorded urticaria among UK Biobank women: a population-based prospective cohort study

This prospective cohort study of over 266,000 UK Biobank women found that a history of menopausal hormone therapy is associated with a modestly increased risk of subsequent recorded urticaria, though the small absolute risk difference and potential for residual confounding limit immediate clinical implications and causal conclusions.

Jinrong Zhang, Yim Lai, Yanhui Gao, Wai-kit Ming2026-10-09
📄 medicine

Comparative study of breathing parameters of severe asthma patients under biologic therapy through Breezhaler ® , Turbuhaler ® , NEXThaler ® and Ellipta ® dry powder inhalers

This single-center cross-sectional study demonstrates that severe asthmatic patients undergoing biologic therapy exhibit inhalation performance across four dry powder inhalers comparable to healthy subjects and superior to COPD patients, with their device-specific peak inspiratory flow and inspiratory volume showing strong correlations to baseline spirometric parameters and asthma control test scores.

Árpád Farkas, Alpár Horváth, Izolda Réti, Norbert Ilyés, Botond Havadtői, Balázs Sánta, Erika Kis, Lisa Schwarzkopf, Gab (…)2026-10-09
📄 medicine

Knowledge, Attitudes, Practices, and Associated Factors Regarding Malaria Prevention among Undergraduate Regular Students at Debre Markos University, Ethiopia: A Cross-Sectional Study, 2026

A 2026 cross-sectional study at Debre Markos University, Ethiopia, found that while the majority of undergraduate students possessed good knowledge and positive attitudes toward malaria, fewer than half engaged in effective preventive practices, highlighting a critical gap between awareness and action that requires reinforced community interventions.

Asmamaw Habtamu2026-10-09
📄 medicine

Prevalence and Predictors of Chronic Kidney Disease of Undetermined Cause (CKDu) among Small-Scale Fishers in Northwest Tanzania: Application of DEGREE Protocol

This community-based cross-sectional study in Northwest Tanzania found that approximately 13.6% of small-scale fishers exhibit reduced kidney function suggestive of chronic kidney disease of unknown etiology (CKDu), a condition strongly associated with increasing age and male sex but not independently linked to occupational heat exposure, dehydration, or specific infections after excluding conventional causes.

Kisa H. Kapaga¹˒³˒⁶, Venance Maro¹˒³, Marion Sumari-de Boer⁴˒⁵, Kajiru Kilonzo²˒³2026-10-09
📄 medicine

Emotional Expression, Treatment Discussions, and Peer Support in Online Fibromyalgia Communities: Large-Scale Natural Language Processing Analysis

This study employs large-scale natural language processing on over 66,000 online forum posts to systematically map the emotional landscape, treatment perceptions, and peer support dynamics within the fibromyalgia community, revealing distinct emotional associations with conventional versus experimental therapies and highlighting unmet patient needs that complement traditional clinical insights.

Onyinye Favour Ezike, Fatuma Cisman, Stephen P. Young, Andrew Sean Wilson2026-10-09
📄 medicine

Food noise among U.S. adults: Psychometric evaluation and prevalence estimates from a nationally representative sample

This study utilizes a nationally representative sample of U.S. adults to validate the Food Noise Questionnaire and estimate that food noise affects approximately 4% to 9.5% of the general population, with prevalence rising significantly among women and individuals with higher weight categories, particularly those with obesity.

Branislav Jovanovic, Nickolas Jones, Fengqing Zhang, Alison Holman, Michael Lowe2026-10-09
📄 medicine

Normative values and cut-points for online administration of the Personal Wellbeing Index: A nationally representative study of Australian adults

This nationally representative study of Australian adults establishes updated online-administered norms and cut-points for the Personal Wellbeing Index, demonstrating its effectiveness in identifying low subjective wellbeing and highlighting the importance of measuring wellbeing and mental distress concurrently as distinct aspects of mental health.

Sarah P. H. Khor, Georgie Frykberg, Tanja Capic, Andrew C. Ward, Matthew Fuller-Tyszkiewicz, Matthew Iasiello, Robert A. (…)2026-10-09