4321 papers
Using data from the CHARLS study, this research developed and internally validated a 12-predictor machine learning model that effectively stratifies sarcopenia risk in Chinese older adults with robust discrimination and a high negative predictive value suitable for community-based screening.
This study validates a composite milestone measure for Parkinson's disease progression using a large pooled cohort, identifying key baseline predictors of milestone occurrence and demonstrating its feasibility as a sample-size-efficient endpoint for future disease-modifying clinical trials.
This case report describes a preterm infant with severe bronchopulmonary dysplasia, pulmonary hypertension, and pulmonary vascular disease who developed refractory symptoms and a suspected cor triatriatum due to left atrial remodeling, underscoring the critical need for individualized therapeutic strategies based on specific pathophysiological phenotypes.
This cross-sectional study of 186 Polish medical students reveals that nearly all respondents experience mental health symptoms, with stress, depression, and anxiety peaking during exam periods and clinical years, while identifying pre-existing conditions, sleep quality, and perceived academic pressure as key predictors of severe outcomes like suicidal ideation.
This nationwide population-based study utilizing EPOS 2020 guidelines reveals that chronic rhinosinusitis symptoms are significantly associated with adverse mental health outcomes, particularly perceived stress, depression, and suicidal ideation, with a notably stronger impact observed among women and individuals with severe depression.
This study provides the first integrated assessment of energy metabolism and body composition in patients with Crisponi/Cold-Induced Sweating Syndrome type 1, revealing significantly reduced caloric intake and resting energy expenditure alongside measurable deficits in fat-free mass, thereby highlighting the critical need for tailored nutritional interventions to manage chronic undernutrition in this population.
This seven-year interrupted time series analysis of over 27 million pediatric outpatient visits reveals that China's Zero-COVID policy induced lasting shifts in child health profiles, characterized by post-reopening surges in infectious and hematologic conditions due to an immunity gap and sustained increases in musculoskeletal and congenital disorders, alongside enduring changes in healthcare-seeking behavior.
This retrospective cohort study of 408 young adults (≤40 years) at a tertiary center in Abu Dhabi reveals that STEMI is the predominant presentation of acute coronary syndrome in this demographic, while dyslipidemia, prior myocardial infarction, and multivessel coronary artery disease are independently associated with NSTEMI rather than STEMI.
This study demonstrates that a multimodal, multidisciplinary trauma team training program incorporating TeamSTEPPS principles was feasible and well-received, leading to significant improvements in nontechnical team performance and process metrics during real-world trauma activations, despite no observed changes in specific ATLS protocol adherence.
This paper reports a rare case of a complicated renal hydatid cyst in a 65-year-old man, which was successfully treated with complete cyst excision while preserving the renal parenchyma.