Healthcare resource utilization, direct medical costs, and the temporal trends for patients with major depressive disorder in China: a 6-year retrospective analysis
This 6-year retrospective analysis of over 32,000 patients in Shenzhen, China, reveals that while major depressive disorder imposes significant economic burdens primarily through tertiary hospital inpatient care, the system is characterized by undertreatment in outpatient services and declining costs, highlighting an urgent need to strengthen primary care, optimize referral systems, and implement early intervention strategies.