📄 Category

medicine

13945 papers

📄 medicine

Emotional Expression, Treatment Discussions, and Peer Support in Online Fibromyalgia Communities: Large-Scale Natural Language Processing Analysis

This study employs large-scale natural language processing on over 66,000 online forum posts to systematically map the emotional landscape, treatment perceptions, and peer support dynamics within the fibromyalgia community, revealing distinct emotional associations with conventional versus experimental therapies and highlighting unmet patient needs that complement traditional clinical insights.

Onyinye Favour Ezike, Fatuma Cisman, Stephen P. Young, Andrew Sean Wilson2026-10-09
📄 medicine

Food noise among U.S. adults: Psychometric evaluation and prevalence estimates from a nationally representative sample

This study utilizes a nationally representative sample of U.S. adults to validate the Food Noise Questionnaire and estimate that food noise affects approximately 4% to 9.5% of the general population, with prevalence rising significantly among women and individuals with higher weight categories, particularly those with obesity.

Branislav Jovanovic, Nickolas Jones, Fengqing Zhang, Alison Holman, Michael Lowe2026-10-09
📄 medicine

Normative values and cut-points for online administration of the Personal Wellbeing Index: A nationally representative study of Australian adults

This nationally representative study of Australian adults establishes updated online-administered norms and cut-points for the Personal Wellbeing Index, demonstrating its effectiveness in identifying low subjective wellbeing and highlighting the importance of measuring wellbeing and mental distress concurrently as distinct aspects of mental health.

Sarah P. H. Khor, Georgie Frykberg, Tanja Capic, Andrew C. Ward, Matthew Fuller-Tyszkiewicz, Matthew Iasiello, Robert A. (…)2026-10-09
📄 medicine

Disease Status at Belimumab Initiation and Clinical Outcomes in Childhood-Onset Lupus Nephritis: A Single-Center Retrospective Cohort Study

This single-center retrospective study of 36 children with childhood-onset lupus nephritis treated with belimumab found that initiating therapy during the newly diagnosed phase, rather than after relapse, was significantly associated with higher rates of complete renal response, lupus low disease activity state attainment, and faster glucocorticoid reduction.

Wenqing Wen, Dahai Wang, Yi Lin, Nana Nie, Cui Bai, Jia Liu, Ranran Zhang, Shan Gao, Qiuye Zhang, Hong Chang2026-10-09
📄 medicine

Appointments Do Not Guarantee Higher Patient Satisfaction: Departmental Heterogeneity in Outpatient Waiting Performance

This study reveals that while appointment systems reduce waiting times and increase satisfaction in ophthalmology, they do not yield consistent benefits in gynecology, indicating that department-specific performance and the alignment of actual wait times with patient expectations are more critical determinants of satisfaction than appointment status alone.

HUI Zhang, Kaixin Gong, Ziang Jia, Yi Yang, Lu Zhan2026-10-09
📄 medicine

Population-scale catalogue of clinically actionable pharmacogenomic variation in a large Middle Eastern Levantine cohort

This study presents the largest population-scale pharmacogenomic analysis to date in Jordan, revealing significant regional genetic variations in drug-metabolizing enzymes and establishing that nearly all participants carry at least one clinically actionable genetic variant, thereby providing a critical foundation for implementing precision medicine in the Levant.

Nagham Nafiz Hendi, Laith M. Alawneh, Noureddin Ismail, Rania Abdellatif, Nathir M. Obeidat, Basel Abu-Jamous, Malek Zih (…)2026-10-09
📄 medicine

Development and Validation of a Physiologically Based Pharmacokinetic Model for Riociguat and Its Active Metabolite M1

This study developed and validated a robust physiologically based pharmacokinetic (PBPK) model for riociguat and its active metabolite M1 that accurately predicts complex pharmacokinetic behaviors, including enterohepatic circulation, food effects, hepatic impairment, and drug-drug interactions, thereby supporting clinical dose optimization and risk assessment.

Wanlong Zhang, Huan Lu, Jingjie Pan, Kexin Qiao, Zhi Li, Xiaobing Zhang, Jianing Liu, Jiachang Liu, Tongman Zhao, Jian G (…)2026-10-09
📄 medicine

Closing the Gap Between Public Health and Clinical Care: A Health Systems Analysis of Ghana's Institutional Public Health Unit Model

This narrative review analyzes Ghana's unique model of embedding Public Health Units within hospital governance structures as a replicable solution to the clinical-public health divide in low- and middle-income countries, identifying 40 implemented facilities while highlighting critical needs for dedicated financing, workforce development, and clarified accountability to ensure sustainable integration.

Isaac Tabiri Henneh, Thomas Hinneh, Patriot Ofori-Aning, Bright Anyimah Oduro, Hosea Boakye, Dennis Miezah, Danaa Alhasa (…)2026-10-09
📄 medicine

From aid dependence to domestic resource mobilization: a policy analysis of financing universal health coverage in Somalia

This policy analysis argues that Somalia must transition from fragile aid dependence to a sequenced, multi-channel domestic resource mobilization strategy—prioritizing immediate efficiency gains, followed by health and broad-based taxes, and long-term insurance and Islamic finance—to achieve universal health coverage amidst external funding cuts.

Prof Dr Abdulrazaq Yusuf Ahmed, Aways Hussein Mohammed, Mohamed Hussein Mohamed2026-10-09
📄 medicine

Sustained-release Ag₂O/UiO-66@Heracleum persicum nanocomposite exhibits potent antibacterial and antibiofilm activities against vancomycin-resistant Staphylococcus aureus

This study demonstrates that a sustained-release Ag₂O/UiO-66@Heracleum persicum nanocomposite effectively combats vancomycin-resistant Staphylococcus aureus urinary tract infections by exhibiting potent antibacterial and antibiofilm activities, downregulating resistance and biofilm-associated genes, and maintaining high cytocompatibility.

Sara Kianifar, Fatemeh Ashrafi, Elham Siasi, Pedram Heidari2026-10-09