13981 papers
This study demonstrates that ginsenoside Rg1 ameliorates hippocampal damage and improves ASD-like behaviors in a VPA-induced rat model by modulating SIRT1 expression to normalize inflammatory, apoptotic, and autophagic pathways.
This qualitative study of 21 lesbian patients in Germany reveals that while heteronormative assumptions and knowledge gaps create barriers in primary care, patients navigate these challenges through either protective concealment or affirmed identity orientations, underscoring the need for provider training, structural changes, and culturally humble communication to improve healthcare experiences.
This study empirically evaluates Shanghai's employer-based Mutual Medical Aid Programme for Retired Workers using social solidarity theory, finding that while the initiative effectively achieves risk sharing and fosters organizational belonging through high coverage and seamless service, it requires improvements in payment transparency, benefit scope, and cross-employer equity to fully address beneficiaries' knowledge gaps and evolving needs.
This study demonstrates that residents in Guangzhou with high consumption of traditional homemade peanut oil exhibit significantly elevated serum aflatoxin B1-lysine adduct levels and an increased risk of liver function abnormalities compared to those with ordinary consumption.
This cross-sectional study at a tertiary hospital in Tanzania found a 2.15% prevalence of multidrug-resistant *Candida auris* bloodstream infections among adult ICU patients, identifying prolonged hospital stays and immunosuppression as key risk factors while highlighting significant resistance to fluconazole and variable susceptibility to other antifungals.
This study explores diverse Scottish family caregivers' perspectives on the SUGEST machine learning tool, revealing that while they view earlier identification of palliative care needs as valuable for enabling timely planning and support, its acceptability and successful implementation depend on transparent data, clinician oversight, compassionate communication, and robust pathways to action.
This study identifies a novel allosteric binding site at the dimer interface of the citrate transporter NaCT (SLC13A5) and discovers a chemically distinct series of small-molecule inhibitors through virtual screening and structural analysis, offering a new foundation for developing therapeutic modulators for metabolic and neurological diseases.
A descriptive cross-sectional survey of 380 students in Sabon Gari, Nigeria, reveals that poor health habits such as junk food consumption, skipping breakfast, and excessive screen time are prevalent among adolescents and are significantly influenced by peer pressure, family context, and media exposure, underscoring the need for integrated multi-level health interventions.
This study developed the updated 2021 Portuguese European Deprivation Index (EDI-PT 2021) using census and survey data to map territorial inequalities and confirmed its strong, dose–response association with all-cause mortality across parish and municipality levels, establishing it as a robust tool for public health surveillance and planning.
Myrrh-mediated silver nanoparticles synthesized using *Commiphora myrrha* extract exhibit potent antibacterial activity against *Staphylococcus aureus* and *Pseudomonas aeruginosa* while maintaining favorable cytocompatibility with normal oral epithelial cells, suggesting their potential for oral therapeutic applications pending further clinical studies.