7906 papers
In patients undergoing laparoscopic cholecystectomy, pre-induction administration of oxycodone significantly accelerated early postoperative recovery metrics such as eye-opening and extubation times compared to administration at skin closure, while both timing strategies yielded comparable overall quality of recovery at 24 hours.
This study identifies Enolase 1 (ENO1) as a critical immunometabolic hub in HBV-related hepatocellular carcinoma that links glycolytic reprogramming and HBV replication to immune evasion, thereby driving tumor progression and representing a promising prognostic biomarker and therapeutic target.
This case series of 15 patients demonstrates that a personalized airway management strategy, prioritizing fiberoptic bronchoscopy-guided intubation and the use of bronchial blockers for lung isolation, effectively ensures safety and surgical success in patients with tracheoesophageal fistulas undergoing surgery after prior stent placement.
This case report details a rare instance of *Klebsiella pneumoniae*-induced sepsis and subsequent fetal loss following multifetal pregnancy reduction, emphasizing the critical need for preoperative microbiome screening and multidisciplinary management to prevent postoperative intrauterine infections in assisted reproductive procedures.
This study finds that while elevated standard C-reactive protein levels independently predict shorter time to death in geriatric outpatients, this prognostic signal is significant only for those under 80 years old and is absent in the oldest-old, indicating that CRP should be interpreted with age awareness rather than used as a standalone marker.
This study identified gaps between pre-clerkship clinical skills curricula and clerkship expectations, demonstrating that a targeted, near-peer-led orientation intervention significantly improved third-year students' preparedness, equipment familiarity, and confidence across key clinical domains.
Using a modified Delphi study grounded in the Competency Onion Model, this research established a reliable and practical five-dimensional competency framework comprising 73 indicators to standardize instructor training for burn and wound healing specialist nurses in China.
This scoping review identifies that access to brain tumor care in Angola is hindered by systemic bottlenecks across the entire diagnostic and therapeutic continuum, necessitating a coordinated approach to strengthen clinical pathways, imaging and surgical capacity, pathology, radiotherapy, and financial protection rather than relying on isolated technical interventions.
This study demonstrates that the concurrent delivery of platelet-rich plasma (PRP) and human umbilical cord mesenchymal stem cells (hUC-MSCs) significantly enhances the treatment of diabetic erectile dysfunction in rats compared to monotherapies or sequential administration, primarily by improving stem cell persistence, attenuating TGF-β1/Smad-mediated fibrosis, and normalizing extracellular matrix remodeling through integrin α7-related signaling.
This retrospective study demonstrates that implementing a shared decision-making-based, multidisciplinary precision management model via a hybrid online/offline approach significantly improves maternal and fetal survival rates and clinical outcomes for pregnant women with advanced chronic kidney disease or on dialysis.