3171 papers
This study demonstrates that peripheral blood neutrophil-to-lymphocyte ratio (NLR) is a sensitive biomarker for age-associated systemic inflammation in osteoarthritis but fails to reflect mechanically driven disease progression or radiographic severity, highlighting distinct inflammatory endotypes within the condition.
This multicentre cross-sectional study in Brazzaville, Republic of the Congo, reveals that severe paediatric malaria carries a high in-hospital mortality rate of 18%, driven primarily by acute kidney injury and age under five, while pre-hospital self-medication and delayed consultation are the key modifiable factors contributing to severe disease.
This cross-sectional study of nurses in Gaza Strip governmental hospitals reveals that while their practical management of childhood convulsions is high, their theoretical knowledge is only moderate, though the two are significantly positively correlated.
This retrospective cohort study utilizing the MIMIC-IV database demonstrates that the Endothelial Activation and Stress Index (EASIX), calculated from routine laboratory values within the first 24 hours of ICU admission, is independently associated with an increased risk of delirium in septic patients when accounting for death as a competing risk.
This cross-sectional study utilizing ISSP 2021 data reveals that while internet access and usage generally promote complementary and alternative medicine (CAM) use, the effects diverge significantly when distinguishing between complementary and alternative medicine, highlighting the critical need to differentiate these concepts in future research.
This county-level study in the United States reveals that higher food insecurity and poorer food environments are independently associated with increased bronchus and lung cancer-related mortality, highlighting the need to integrate food security into cancer prevention strategies to address persistent socioeconomic and geographic disparities.
This study validates the Ukrainian version of the Prolonged Grief Assessment for Children (PGA-C) as a reliable and valid tool for identifying clinically significant grief among bereaved youth living in wartime conditions, demonstrating excellent internal consistency, strong test-retest reliability, and robust convergent and divergent validity despite a limited fit for its proposed two-factor structure.
This cross-sectional study of 400 outpatients reveals that while preventive practices declined post-pandemic, a significant portion of patients experienced unreported mild adverse events from COVID-19 vaccines and drugs, with self-medication identified as a key risk factor and vaccine safety concerns as the primary barrier to prevention.
This post-hoc analysis of a randomized controlled trial suggests that adjunctive esketamine significantly improves anhedonia in adolescents with moderate-to-severe major depressive disorder over the long term, with therapeutic effects becoming evident from Day 12 onward.
This study developed and validated a prognostic nomogram based on four independent clinical variables (extrahepatic metastasis, elevated alkaline phosphatase, elevated lactate dehydrogenase, and locoregional therapy) to effectively stratify survival outcomes for patients with BCLC stage C hepatocellular carcinoma receiving first-line targeted therapy plus immunotherapy.