📄 Category

medicine

7907 papers

📄 medicine

Clinical Outcomes of Pregnancy in Women with Advanced Chronic Kidney Disease and on Dialysis: A Shared Decision-Making and Multidisciplinary Precision Management Approach

This retrospective study demonstrates that implementing a shared decision-making-based, multidisciplinary precision management model via a hybrid online/offline approach significantly improves maternal and fetal survival rates and clinical outcomes for pregnant women with advanced chronic kidney disease or on dialysis.

Xun Mao, Lili Cheng, Mingfang Zhou, Yushuang Qin, Shan Hu, Juan Huang, Xin Xi, Qian Du, Liyan Wang, En Tian, Lirong Lin (…)2026-09-03
📄 medicine

Nonlinear Symptom Escalation and Residual Burden After Recovery in Adolescent Depression: Cross-Validated Trajectory Analysis in 2,809 Chinese Adolescents

This three-year longitudinal study of 2,809 Chinese adolescents identified four distinct depressive symptom trajectories, revealing that a small subgroup experiences nonlinear, accelerating symptom escalation while another subgroup retains significant residual burden despite improvement, with findings validated by high cross-method agreement and linked to specific demographic and clinical predictors.

Juan Zhang, Wen Wang, Fang Wang, Yujie Liu, Di He, Lianzhong Liu2026-09-03
📄 medicine

Concurrent procedures during caesarean delivery and early postoperative deep vein thrombosis detection: a retrospective cohort study

This retrospective cohort study of 1,943 women found no significant association between concurrent procedures during caesarean delivery and early postoperative deep vein thrombosis detection, suggesting that the current RCOG practice of adding a uniform three-point risk increment for such procedures increases the number of women qualifying for prophylactic heparin without improving risk discrimination.

Yong Sun, Yuxin Bi, Wenjie Zhang, Ling Wang, Huan Zhang, Yao Tan2026-09-03
📄 medicine

The role of geriatric syndromes in moderating the relationship between cardiometabolic multimorbidity and cognitive function in mid-to-late life: a multicohort study

This multicohort study demonstrates that geriatric syndromes, particularly frailty, depressive symptoms, and their cumulative or progressive trajectories, significantly modify and exacerbate the negative association between cardiometabolic multimorbidity and cognitive function in mid-to-late life.

Yating Liu, Xiang Li, Xin Yang, Guangwen Liu, Chenlu Hong, Yujie Huang, Boyuan Guan, Xueheng Wang, Chong Chao, Yanan Luo2026-09-03
📄 medicine

Prevalence of pneumonia and associated risk factors among neonates in selected health facilities in Wakiso district, Uganda

This cross-sectional study in Wakiso district, Uganda, found a 12.6% prevalence of neonatal pneumonia and identified that factors such as lack of antenatal care, prematurity, low birth weight, limited caregiver knowledge, and specific cooking conditions (using charcoal in living-room-attached kitchens) are significantly associated with the condition, highlighting the need for targeted interventions for these high-risk groups.

Bridget Namwanga, Mathius Amperiize, David Musoke, Edith Nakku Joloba, Angela Kisakye2026-09-03
📄 medicine

Antimicrobial resistance patterns in pregnancy and their relationship to early onset Neonatal infection in tertiary level hospitals in Rwanda

This study of pregnant women and their newborns in Rwandan tertiary hospitals reveals a high prevalence of antimicrobial-resistant bacterial infections, particularly among Gram-negative pathogens like *Klebsiella pneumoniae* and *Escherichia coli*, with a significant proportion of neonatal infections directly linked to maternal strains, highlighting the urgent need for improved antimicrobial stewardship and routine screening.

Jean Pierre Bucyebucye, Patrick G. Bagambe, Kenneth Ruzindana, Aimable Kanyamuhunga, Emmanuel Habimana, Stephen Sabiti (…)2026-09-03
📄 medicine

Development and temporal validation of the PRE-DELIRIUM score for postoperative delirium in older adults with hip fracture

This study developed and temporally validated the PRE-DELIRIUM score, a practical five-variable preoperative model incorporating age, cognitive impairment, and blood urea nitrogen, which effectively predicts postoperative delirium risk in older adults with hip fractures to facilitate early prevention strategies.

Unchana Sura-amonrattana, Suparat Saetan, Pornjuree Saepoo, Varalak Srinonprasert, Direk Tantigate, Manatchanok Kunin, R (…)2026-09-03
📄 medicine

The AI-CDSS Evidence Gap: A Critical Analysis of Outcome Measurement, Human-AI Interaction, and Implementation Validation

This critical narrative review reveals that current evidence for AI-based clinical decision support systems is insufficient to demonstrate meaningful patient benefits, as it relies heavily on surrogate diagnostic metrics, overlooks significant human-AI interaction risks like automation bias, and lacks prospective validation in diverse real-world settings, particularly in low- and middle-income countries.

Joy Aifuobhokhan, Daniel Adurayemi Idowu, Ugochukwu Leonard Chibuike, Nathaniel Oluwabukunayomi Solomon, Agbeko Emmanuel (…)2026-09-03
📄 medicine

Mechanistic Pathways of Biochemical and Toxicological Responses to Waste Tyre Combustion Emissions: A Systematic Review

This systematic review synthesizes limited but emerging evidence indicating that waste tyre combustion emissions induce multi-organ toxicity primarily through oxidative stress and inflammatory pathways, highlighting an urgent need for more rigorous, longitudinal, and molecular-level studies to fully characterize these health risks.

Stephen Kusi, Christopher Larbie, Benjamin Obukowho Emikpe, Lyndon Sackey, Jackson Adiyiah Nyantakyi2026-09-03
📄 medicine

Comparison of level of Engagement, Empathy, and Motivation among 2nd year MBBS students with early and conventional clinical exposure, A comparative cross-sectional study

This comparative cross-sectional study of 423 second-year MBBS students in Pakistan found that those with early clinical exposure demonstrated significantly higher academic engagement and empathy than their peers in traditional curricula, though no difference in motivation was observed, suggesting that while early clinical exposure is beneficial, it should be integrated with other strategies to maximize its impact.

Meerab Ali khan, Ali Hassan, Eman Fatima, Muhammad Yousaf, Waseem Sajjad Shah, Muhammad Raza Ansari, Basira Bek, Hamza H (…)2026-09-03