📄 medicine

Comparison of level of Engagement, Empathy, and Motivation among 2nd year MBBS students with early and conventional clinical exposure, A comparative cross-sectional study

This comparative cross-sectional study of 423 second-year MBBS students in Pakistan found that those with early clinical exposure demonstrated significantly higher academic engagement and empathy than their peers in traditional curricula, though no difference in motivation was observed, suggesting that while early clinical exposure is beneficial, it should be integrated with other strategies to maximize its impact.

Meerab Ali khan, Ali Hassan, Eman Fatima, Muhammad Yousaf, Waseem Sajjad Shah, Muhammad Raza Ansari, Basira Bek, Hamza H (…)2026-09-03
📄 medicine

The Association Between the Gamma-Glutamyl Transferase-to-Albumin Ratio and the No-Reflow Phenomenon in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

This study demonstrates that the Gamma-Glutamyl Transferase-to-Albumin Ratio (GAR), a marker derived from routine admission tests, is an independent predictor of the no-reflow phenomenon in patients with acute coronary syndrome undergoing percutaneous coronary intervention.

Onur Akgün, Murat Akdoğan, Çağatay Tunca, Sinan Boz, Mustafa Duran2026-09-03
📄 medicine

Latent profiles of kinesiophobia and associated factors in older patients after hip arthroplasty: a cross-sectional study

This cross-sectional study of 307 older patients in China identified three distinct latent profiles of kinesiophobia following hip arthroplasty and determined that factors such as surgical history, frailty, pain, and social support significantly influence profile membership, highlighting the need for targeted perioperative interventions.

jiayu zhou, Xin Ling, Jia Yao, Lijun Xiang, Xu Peng, Yi Yin2026-09-03
📄 medicine

Anesthetic Management of a Parturient with Asymptomatic Second-Degree 2:1 Atrioventricular Block for Emergency Lower Segment Cesarean Section: A Case Report

This case report demonstrates that general anesthesia can be safely administered to an asymptomatic parturient with second-degree 2:1 AV block undergoing an emergency cesarean section without prophylactic pacemaker insertion, provided that management is guided by multidisciplinary risk stratification, continuous invasive monitoring, and immediate resuscitative support.

Sunakshi Bhatia, DILJOT KAUR, MOHAMMED SUHAIL A, NISHTHA VIJ2026-09-03
📄 medicine

Real-world outcomes associated with initial oral CGRP receptor antagonist integration strategies in children and adolescents with migraine: a multicenter cohort study

This multicenter cohort study of 109 children and adolescents with migraine found that adding rimegepant to conventional preventive therapy was associated with numerically higher response rates for reducing monthly headache days compared to conventional therapy alone, particularly for achieving a ≥75% reduction, though the primary outcomes did not reach statistical significance, suggesting a need for further prospective evaluation.

Zexian Zhao, Jingxin Fu, Jinyi Song, Mengting Zhou, Feifan Liu, Yuhui Xia, Mengna Yang, Han Xiao Pan, Linli Gao, Jiahuan (…)2026-09-03
📄 medicine

Intra-arterial methylene blue injection for parathyroid preservation in thyroid surgery

This prospective study demonstrates that intra-arterial methylene blue injection is a feasible and effective adjunct for intraoperative parathyroid localization during thyroidectomy, significantly aiding gland preservation when combined with frozen section confirmation despite the dye's limited specificity.

Sonali Sharma, Sarita Asotra, Ishan Chauhan, Ramesh Azad, Sarita Negi, Jagdeep Thakur2026-09-03
📄 medicine

A 10-year Cancer Registry Analysis on Demographic, Clinicopathological, and Treatment Characteristics for Head and Neck Cancer Patients in Zambia

This 10-year retrospective analysis of Zambia's national cancer registry reveals that head and neck cancer predominantly affects males, presents at advanced stages, and is treated primarily with chemotherapy, with oral cavity tumors being most common in adults and nasopharyngeal tumors in adolescents.

Chrispinus Hakimu Mumena, Jenny Öhman, Bengt Hasséus, Christopher Kapeshi, Daniel Giglio2026-09-03
📄 medicine

Psychometric Validation and Cultural Adaptation of the Functional Vision Questionnaire for Children (FVQ-Ar): A COSMIN-Compliant Study

This study successfully cross-culturally adapted and psychometrically validated the Arabic Functional Vision Questionnaire for Children (FVQ-Ar) in Jordan, demonstrating excellent reliability and validity to support evidence-based educational accommodations and inclusive education for visually impaired students in the Middle East.

Ayah Ibrahim Al-Rababah, Muawyah Al Bdour, Yazan Gammoh, Óscar García Espinilla2026-09-03
📄 medicine

Modelling the future population health consequences of precipitation-induced healthcare disruptions in Malawi

This study utilizes a modeling framework integrated with Malawi's Thanzi La Onse health system model to project that precipitation-induced disruptions between 2025 and 2040 will significantly impact acute conditions like neonatal care and respiratory infections, affecting over 7 million people and highlighting the critical need for adaptation planning and improved data on patient behavior.

Rachel Murray-Watson, Tara Mangal, Bingling She, Sangeeta Bhatia, Andrew Philips, Joseph Collins, Timothy Hallett, Margh (…)2026-09-03
📄 medicine

A Case Report on Endometrial Dedifferentiated Carcinoma with a Comprehensive Literature Review

This case report highlights a diagnostic challenge where a rare FIGO stage IA dedifferentiated endometrial carcinoma in a 33-year-old woman was initially misdiagnosed as cervical high-grade neuroendocrine carcinoma, underscoring the critical need for comprehensive tissue sampling and judicious immunohistochemistry to ensure accurate staging and appropriate management.

Yue Huang, Hongxin Yu, Yaqian Feng, Qi Guo, Xiaoxue Wang, Lina Hu, Jingfen Sun, Haixia Shang2026-09-03