Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and cardiovascular mortality among US adults with diabetes: a prospective cohort study of NHANES 1999–2018
This prospective cohort study of US adults with diabetes found a modest, nonlinear association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and cardiovascular mortality, where higher NHHR values above an apparent nadir of approximately 2.5–3.0 were linked to an increased risk, though the findings warrant cautious interpretation and further validation.