📄 Category

medicine

14263 papers

📄 medicine

Associations of initial blood gas parameters with post-cooling MRI-derived brain volumes and Rutherford injury scores in neonatal hypoxic-ischemic encephalopathy: a retrospective exploratory study

This retrospective study of 79 neonates with hypoxic-ischemic encephalopathy found no significant associations between initial blood gas parameters and post-cooling MRI-derived brain volumes or Rutherford injury scores after correcting for multiple comparisons, suggesting that these initial metabolic markers may not reliably predict structural brain injury severity in this context.

Mehmet Burak ozkan, Hasan Bulut, Furkan Özdem, Enes Özsozgun, Sariye elif özyazici özkan2026-10-12
📄 medicine

Fever-negative malaria parasitaemia and anaemia among children in Burkina Faso: a cross-sectional analysis linking microscopy andcaregiver reports in the 2021 Demographic and Health Survey

This cross-sectional analysis of the 2021 Burkina Faso Demographic and Health Survey reveals that relying solely on caregiver-reported fever misses a substantial proportion of children with malaria parasitaemia, who nonetheless face a high burden of anaemia, highlighting the limitations of symptom-triggered care in this setting.

Amos Langat2026-10-12
📄 medicine

TMS-EEG Investigation of Cortical Activity Induced by Individualized rTMS in Patients with Prolonged Disorders of Consciousness

This study demonstrates that individualized rTMS targeting sites with strong directed functional connectivity, guided by resting-state EEG, significantly improves behavioral recovery and enhances sustained cortical activity propagation in patients with prolonged disorders of consciousness more effectively than conventional fixed-target stimulation.

Ye Zhang, Xiao Yan, Zilong Zhu, Jubao Du, Lei Cao, Weiqun Song, Yong Wang2026-10-12
📄 medicine

Effects of Maxillary Skeletal Expansion on Craniofacial Structures and Temporomandibular Joints in Adults with Skeletal Class III Malocclusion: A Retrospective Cone-Beam Computed Tomography Study

This retrospective CBCT study demonstrates that maxillary skeletal expansion in adults with skeletal Class III malocclusion induces a coordinated three-dimensional craniofacial response, characterized by lateral and anteroinferior displacement of the zygomaticomaxillary complex, posterior mandibular rotation, and significant increases in temporomandibular joint spaces and condylar cross-sectional areas.

Lin Li, Qian Zhao, Fei Peng, Zhe Ma, Xiaoli Guo, Pengxu Chen, Baocheng Cao2026-10-12
📄 medicine

Astragaloside IV and ginsenoside Rb1 combination improves diabetic foot ulcer healing by downregulating the IRF1-ZBP1 axis in keratinocytes

This study demonstrates that the synergistic combination of astragaloside IV and ginsenoside Rb1 accelerates diabetic foot ulcer healing by directly binding to and downregulating the IRF1-ZBP1 axis, thereby suppressing PANoptosis in keratinocytes.

Zhonghua Fu, Xinbei Zhang, Zhengying Jiang, Jinwei Shang, Xincheng Liao, Hang Luo, Zhenfang Xiong2026-10-12
📄 medicine

Primary malignant peripheral nerve sheath tumor of the vagina: a rare case report

This case report describes a rare instance of primary malignant peripheral nerve sheath tumor of the vagina in a 67-year-old woman, highlighting its aggressive nature through rapid local recurrence and distant metastasis one year after surgery despite initial complete resection, thereby underscoring the critical need for adjuvant therapy and rigorous long-term surveillance.

Zhenwei Gao, Fangli Wei, Nana Yin, Chujun Zhan, Siyuan Sun, JiangYing Zhu2026-10-11
📄 medicine

Ambient temperature and the volume and severity of 621,790 myocardial infarction admissions. A national case-crossover study

This national case-crossover study utilizing Brazilian and MIMIC-IV data demonstrates that while extreme temperatures modestly affect the volume of myocardial infarction admissions, they do not shift the severity of cases toward intensive care or death, and it further validates that ICU stays are a more reliable marker of clinical severity than diagnostic codes.

Ahmet DEMIR, Kemal GOKCEK, Ahmet AKSAKAL, Olcay KORKMAZ, Ömer Doğan ALATAS, Mete Ucdal2026-10-11
📄 medicine

Stage at Presentation and Clinical Characteristics of Breast Cancer Patients at the Butaro Cancer Centre of Excellence, Rwanda: A Retrospective Chart Review

This retrospective chart review of 300 breast cancer patients at Rwanda's Butaro Cancer Centre of Excellence reveals that the majority are diagnosed at a younger age with a high burden of modifiable risk factors and comorbidities, and nearly half present with late-stage disease, underscoring the urgent need for enhanced early-detection strategies in resource-limited settings.

Jean Paul Majyambere, Betel Amdeslassie Fenta, Naol Belema Gemechu, Phillip J. Hsu, Anteneh Gadisa Belachew, Anne Niyige (…)2026-10-11
📄 medicine

Evaluative (Mis)alignment in Competency-Based Feedback: A Constructivist Grounded Theory-Informed Study in Family and Community Medicine Residency Programs 

This constructivist grounded theory study of family medicine residency programs in Brazil reveals that evaluative misalignment between residents and preceptors stems from divergent reasoning rather than scoring discrepancies, leading to the development of the S-SKILLS-F framework to transform feedback into a negotiated, actionable process for professional growth.

Hamana Oliveira Queiroz Bessa, Wellington Pedro de Sousa, Edinete Nunes da Silva, Rafaela de Albuquerque Paulino, Daiane (…)2026-10-11
📄 medicine

Kinderleicht: Auf die Reha, fertig, los! (Easy as Pie: Ready, Set, Rehab!) – Participatory development of a personalized activity book to prepare primary school-aged children for inpatient rehabilitation: a study protocol

This study protocol outlines the participatory development, iterative testing, and evaluation of a personalized activity book designed to age-appropriately prepare primary school-aged children for inpatient medical rehabilitation by involving children, parents, and professionals in its creation.

Tuğba Aksakal, Christian Kempny, Yüce Yılmaz-Aslan, Patrick Brzoska2026-10-11