4321 papers
This study of 204 pregnant individuals in an integrated obstetric behavioral health program found that higher treatment dosage was associated with improved birth outcomes and significantly greater reductions in depressive symptoms, particularly for those with histories of childhood maltreatment.
This study utilizes cortical functional gradient heterogeneity to classify Parkinson's disease patients into neuropsychiatric and non-neuropsychiatric subtypes, linking these macroscopic functional alterations to specific microscopic neurotransmitter gene expression patterns to better explain clinical heterogeneity.
This paper outlines the protocol for a single-centre, randomised controlled feasibility trial in Pakistan designed to assess the feasibility and acceptability of delivering a task-shifted Behavioural Activation intervention (TASK-BA) by trained non-specialists to haemodialysis patients with depression, compared to enhanced usual care, to inform a future definitive trial.
This prospective cohort study of 328 Chinese primiparous women reveals that exercise frequency, rather than duration or intensity, is a significant independent protective factor against excessive gestational weight gain, with each additional weekly exercise day associated with a 0.21 kg reduction in total weight gain.
This exploratory population-based registry-linkage study of 302,439 singleton births in Slovenia (2005–2017) identified significant crude associations between ASD diagnosis and male sex, preterm birth, postpartum hemorrhage, cesarean delivery, and neonatal respiratory morbidity, though the authors caution that the lack of multivariable adjustment and potential confounding limit causal inference.
This study demonstrates that mitragynine, the primary alkaloid in kratom, alters glucose homeostasis in male mice through insulin-independent mechanisms, causing acute hyperglycemia and chronic glycemic improvements via liver function and inflammation reduction, while operating independently of insulin AKT signaling and vagal sensory pathways.
This randomized controlled trial demonstrates that an 8-week program combining blood flow restriction with low-intensity functional training effectively improves lower-limb strength, specific strength-balance metrics, and sprint performance in amateur badminton players, offering a viable low-load alternative to high-intensity training.
This Level III retrospective cohort study demonstrates that bichectomy significantly reduces the volume and area of the middle and lower face by removing an average of 4.10 ml of fat per side, with these measurable changes being independent of the patient's body mass index.
This observational cohort study demonstrates that elevated circulating FSTL1 levels serve as an independent predictor for the progression of renal function in patients with type 2 diabetes mellitus and chronic kidney disease, suggesting its potential utility as a prognostic biomarker.
This retrospective national cohort study from Kazakhstan demonstrates that despite limited access to molecular diagnostics, standard multimodal therapy achieves long-term survival rates comparable to international benchmarks, with age and metastatic stage identified as the primary prognostic determinants for pediatric medulloblastoma.