📄 Category

medicine

14263 papers

📄 medicine

Acute Respiratory Impacts of Fine Particulate Matter (PM2.5) in Kinshasa: Epidemiological Evidence and Pulmonological Implications

This hospital-based case-crossover study in Kinshasa (2018–2022) provides the first clinical evidence that short-term increases in PM₂.₅ concentrations are significantly associated with higher rates of acute respiratory admissions among adults, particularly those aged 35–64, highlighting the urgent need for improved air quality surveillance and environmental health integration in sub-Saharan Africa.

Mélanie Ngutuka Kinzunga, Daniel Masisa Matondo, Zacharie Tsala Dimbuene, Noussair Lazrak, Kevin Cromar, Paulson Isevula (…)2026-10-11
📄 medicine

MV‑Flow imaging for predicting adverse pregnancy outcomes in gestational diabetes mellitus

This study demonstrates that lower third-trimester placental vascular index in the mid-region (VIMed), measured via MV-Flow ultrasound, is significantly associated with adverse perinatal outcomes in gestational diabetes mellitus and enhances the predictive accuracy of a risk-stratification model when combined with pre-pregnancy BMI and fasting OGTT glucose.

Qingxia Zhu, Huimin Hu, Fang Yang, Jun Shi, Guilan Yang2026-10-11
📄 medicine

Social well-being is associated with slower multisystem aging estimated from a single brain MRI scan: prospective evidence from MIDUS

Using data from the MIDUS study, this research demonstrates that social well-being, distinct from other dimensions of subjective well-being, is prospectively associated with a slower pace of multisystem biological aging as estimated by a novel single-scan brain MRI biomarker.

Minwoo Lee, Sara M. Garza-Gonzalez, Stacey M. Schaefer, Kyle Bourassa, Casey K. Brown2026-10-11
📄 medicine

Ultrasound-detected hepatic steatosis in psoriatic disease: prevalence, cardiometabolic correlates, and biochemical discordance

This cross-sectional study of 534 psoriatic adults reveals that ultrasound-detected hepatic steatosis affects approximately one-quarter of patients, is primarily driven by central adiposity rather than skin or joint severity, and often occurs despite normal aminotransferases, suggesting gamma-glutamyl transferase (GGT) as a promising secondary marker for detection.

Rubén Queiro, Inés Molinos, Arancha Gómez-Cosme, Pablo Coto-Segura2026-10-11
📄 medicine

Comparative Reliability of Gemini and NotebookLM on AAPD Guideline-Based Pediatric Dentistry Multiple-Choice Questions: Accuracy, Consistency, and Error-Pattern Analysis

This study demonstrates that while Retrieval-Augmented Generation (RAG) significantly enhances the consistency and stability of AI responses to pediatric dentistry guideline questions compared to standalone models, it does not fully eliminate systematic evidence-mapping errors, suggesting that future AI evaluations must prioritize reliability frameworks over simple accuracy metrics.

Junsheng Lao, Linyong Xu2026-10-11
📄 medicine

Cerebrospinal fluid Th1/Tc1 polarization in a patient with first-line immunotherapy-resistant GFAP astrocytopathy: a case report

This case report describes a patient with first-line immunotherapy-resistant GFAP astrocytopathy whose pretreatment cerebrospinal fluid exhibited a Th1/Tc1-polarized cytokine profile, suggesting that CD8⁺ cytotoxic T cell-mediated injury may underlie treatment refractoriness and warrant early escalation to second-line immunotherapy.

Tie-jun Yang, Long-nan Wang, Pan-kui Li, Chun-bo Ji, Si-qing Ma, Xiu-ying He, Ping Yang2026-10-11
📄 medicine

Salt-Sensitivity Trait and Coronary Microvascular Function in New-Onset Hypertension

This study indicates that while new-onset hypertensive patients generally exhibit impaired coronary microvascular function compared to controls, those with salt-sensitive hypertension—particularly when defined by systolic blood pressure changes—demonstrate more pronounced dysfunction than their salt-resistant counterparts.

Ayse Parali Ak, Fatma Betul Celik, Tolga Sinan Güvenç, Ahmet Eren Caliskan, Merve Kapcik, Narmin Ismayilzada, Yusuf Yilm (…)2026-10-11
📄 medicine

A Four-Year Retrospective Analysis (2021–2024): The Impact of Prior Antibiotic Exposure on CRE Infection Prevalence and Antibiogram Profiles in a Tertiary Care Setting

This four-year retrospective study in a tertiary care setting in Chattogram, Bangladesh, reveals that prior antibiotic exposure, particularly to carbapenems and cephalosporins, is strongly associated with the emergence of multidrug-resistant CRE infections, while identifying colistin and tigecycline as the most effective remaining therapeutic options against a pathogen that carries a high mortality rate.

Zaved Mehedi Hasan, Md. Akram Hossain, Showrov Sen Emu, Nayeem Uddin, Muhammed Abdul Quader, Harun Ur Rashid, Ayesha Ahm (…)2026-10-11
📄 medicine

A postmortem case of fulminant anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis with markedly elevated cerebrospinal fluid IL-6: a case report

This case report describes a fatal, fulminant anti-AMPAR encephalitis in an 84-year-old woman characterized by markedly elevated cerebrospinal fluid IL-6 levels and prominent CD8-positive T-cell infiltration, highlighting the potential severity of this condition even in the absence of an underlying malignancy.

Hisatsugu Tachibana, Takako Okubo, Tatsuo Matsushita2026-10-11
📄 medicine

A Model-Informed Evaluation of Three-Times-Daily Levetiracetam Dosing in Epilepsy: A Population Pharmacokinetic and Simulation Study

This population pharmacokinetic study and simulation demonstrate that while levetiracetam dosing is influenced by body weight and concomitant medications, a three-times-daily regimen provides more stable plasma concentrations compared to twice-daily dosing, potentially leading to longer seizure-free periods in epilepsy patients.

Waad Hasan Alkathiri, Bander Sameer Balkhi, Aliyah Almomen, Bandar Nasser Aljafen, Saeed Ali Alqahtani2026-10-11