📄 medicine

Exploration of the Optimal Dose Combination of Ciprofol and Oxycodone in Painless Oocyte Retrieval: A Randomized Controlled Trial Research

This randomized controlled trial identifies the optimal anesthesia regimen for painless oocyte retrieval as a combination of 0.075 mg/kg oxycodone and 0.35 mg/kg ciprofol, which provides stable hemodynamics, rapid recovery, satisfactory analgesia, and the lowest incidence of adverse reactions compared to other tested dosage combinations.

Xiaowen Yan, Tengchen Feng, Yanlin Chen, Ying Zhu, Jiayi Wang, Xiaoming Ye, Chenxue Meng, Zhiming Lan, Jie Yao2026-07-09
📄 medicine

Timing of Systemic Therapy Initiation in Antepartum and Postpartum Pregnancy- Associated Breast Cancer: A National Claims-Based Analysis

This national claims-based analysis reveals that while pregnancy-associated breast cancer patients generally adhere to guidelines by deferring HER2-directed and endocrine therapies until after delivery, the timing of chemotherapy initiation remains highly variable, with a significant portion of antepartum patients delaying treatment until the postpartum period.

Shifa Kanjwal, Stephanie Rice, Yong Shan, Sharon H. Giordano, Yong-fang Kuo, David S. Lopez2026-07-09
📄 medicine

Awake Craniotomy Without Bispectral Index Monitoring in a Rural Setting of Eastern Indonesia: A Case Report

This case report demonstrates that awake craniotomy can be safely and successfully performed in a resource-limited rural Indonesian hospital without Bispectral Index monitoring by utilizing a structured protocol involving accurate dexmedetomidine dosing, systematic sedation titration via the Ramsay Sedation Scale, and multimodal analgesia.

Ida Bagus Gita Dharma Wibawa, Cokorda Istri Arintha Devi, Ivanmorl Ruspana, Ida Bagus Krisna Jaya Sutawan2026-07-09
📄 medicine

A Tripartite Evolutionary Game Model for Ebola Vaccination and Coordinated Public Health Intervention

This study develops a tripartite evolutionary game model coupling public, government, and institutional behaviors with Ebola transmission dynamics to demonstrate that coordinated intervention significantly outperforms voluntary vaccination alone by accelerating epidemic control and substantially reducing infection and mortality rates.

ZHIQIANG ZENG, XinCai Dai, Feng Ding, Rui Wang, Jing Xin, Huan Zhao2026-07-09
📄 medicine

Optimized Photobiomodulation Protocol Applied After Excision of Sacrococcygeal Pilonidal Cyst: An Exploratory Study

This exploratory randomized trial suggests that adjuvant 660 nm photobiomodulation therapy accelerates wound healing and improves clinical outcomes following sacrococcygeal pilonidal cyst excision, despite limitations related to its small sample size.

Erick Giovanni Reis da Silva, Lucas da Silva Boy, Ivany Machado de Carvalho Baptista, David Pinto Ribeiro, Walter Rodrig (…)2026-07-09
📄 medicine

Wellbeing intervention and support priorities for healthcare workers and their families: A Delphi consensus study

Through a three-round Delphi consensus study involving Australian healthcare workers and their partners, this research identified practical, system-level priorities—such as clear mental health referral pathways, fair compensation, flexible work arrangements, and stable rostering—to enhance workforce wellbeing and retention.

Jade Sheen, Brian Lee, David Skvarc, Emily S. Chan, Elizabeth M. Clancy, Bodil Rasmussen, Alison Hutchinson, Paul Buntin (…)2026-07-09
📄 medicine

Outcomes of fluoroscopy guided stent placement for primary and metastatic malignant obstructive jaundice in unresectable tumors

This retrospective study of 108 patients demonstrates that fluoroscopy-guided self-expandable metal stent placement is a safe and effective palliative treatment for malignant obstructive jaundice caused by both primary and metastatic tumors, with subsequent chemotherapy identified as a key factor in significantly prolonging stent patency for metastatic cases.

Haiyang Lai, Ketong Wu, Yang Liu, Dan Li, Tao Peng, Yuan Wan, Bo Zhang2026-07-09
📄 medicine

Efficacy of Preoperative Warming with Wireless Temperature Monitoring in Laparoscopic Colorectal Cancer Resection: A Randomized Controlled Trial

This randomized controlled trial demonstrates that 30 minutes of preoperative warming, monitored via a wireless iThermonitor®, significantly reduces the incidence and severity of perioperative hypothermia and improves postoperative recovery outcomes in patients undergoing laparoscopic colorectal cancer resection.

Xiangying Gao, wenwen Du, Yanyan Li, Xiuxiao Zhu, Xiujie Wu, Sunrui Yu, Junlu Wang, Qinxue Dai2026-07-09