📄 medicine

Assessment of the knowledge, Attitude and Practice on the relationship between periodontal health and diabetes mellitus among Bangladeshi population: A Cross-sectional Study

This cross-sectional study of Bangladeshi adults with diabetes reveals a significant knowledge–practice gap regarding the bidirectional relationship between periodontal health and diabetes, characterized by generally favorable attitudes but poor knowledge and inadequate oral hygiene practices, highlighting the urgent need for integrated oral health education and preventive care within diabetes management services.

Mustari Nailah Tabassum, Tarannum Mahmood, Sadia Sultana Imla, Bivasa Chakraborty, Tanvir Hossain, Aishee Saha, Md. Maje (…)2026-10-11
📄 medicine

Comparison of Ultrasound Guided Supraclavicular Brachial Plexus Block with and without Peripheral Nerve Stimulation (PNS) Guidance: A randomised controlled trial

This randomized controlled trial demonstrates that while adding peripheral nerve stimulation to ultrasound guidance for supraclavicular brachial plexus blocks does not improve success rates or onset time, it significantly increases procedural duration due to frequent needle re-adjustments, suggesting that ultrasound guidance alone is sufficient for efficient and effective block performance.

Muhammad Azhar Sharafat, Hafiz Muhammad Motsim Tariq, Azhar Rehman2026-10-11
📄 medicine

Predicted fat mass index and incident stroke in adults aged 65 years or older: heterogeneous associations across three national ageing cohorts

This study found that the predicted fat mass index (pBFMI) showed a heterogeneous association with incident stroke across three national ageing cohorts—positively linked in CHARLS but not in ELSA or HRS—and offered no material improvement in model fit or discrimination over BMI.

Shikun Li, Xu Chen, Rudong Chen, Zhuo Yang, Yuyang Hou, Jiasheng Yu2026-10-11
📄 medicine

Development and evaluation of a low fidelity non-living bull’s-penis model for simulated penile fracture repair

This study demonstrates that a low-cost, non-living bovine penile model effectively simulates penile fracture repair, offering high perceived realism and significantly increasing trainee confidence despite limited prior operative experience.

Hai Ho, Luke Chan, Mark Johnson, Patrick Gordon, Stephen R Payne, Vaibhav Modgil, Vishwanath Hanchanale, Chandra Shekhar (…)2026-10-11
📄 medicine

Associations of Depression and Sarcopenia with ADL Disability and All-Cause Mortality in Chinese Older Adults: A 7-Year Prospective Cohort Study

This 7-year prospective cohort study of 4,161 Chinese older adults reveals that while depression independently predicts activities of daily living (ADL) disability and low grip strength predicts mortality, the co-occurrence of depression and sarcopenia confers the highest additive risk for both adverse outcomes, particularly among adults aged 60–69.

Xin Liao, Bingyao Liu, Song Yu, Bin Guo, Ke Yu2026-10-11
📄 medicine

Association between prophylactic pancreatic stent length and post-ERCP pancreatitis: a propensity score–matched cohort study

This propensity score–matched cohort study suggests that using longer prophylactic pancreatic stents (6–9 cm) is associated with a significantly lower incidence of post-ERCP pancreatitis compared to 5-cm stents in high-risk patients, though the findings are considered hypothesis-generating due to the retrospective, non-randomized design.

Menghan Wang, Yijun Chen, Yan Zhao, Wenhai Wang2026-10-11
📄 medicine

Clinical Features and Prognostic Factors of Bone Metastasis in Esophageal Squamous Cell Carcinoma: a retrospective cohort study

This retrospective cohort study of 334 patients with esophageal squamous cell carcinoma and bone metastasis identifies performance status, the number of extrabony metastases, concurrent hepatic metastasis, and the application of local therapy for bone lesions as independent prognostic factors for survival, highlighting the particularly poor prognosis associated with liver involvement.

Yu Yang, Ruojun Xu, Xiaozhi Tang2026-10-11
📄 medicine

Polycystic kidney disease in pregnancy: A retrospective study on obstetric and neonatal outcomes

This retrospective population-based study utilizing the HCUP-NIS database found that pregnant women with polycystic kidney disease face significantly increased risks of hypertensive disorders, preterm delivery, and small-for-gestational-age infants compared to those without the condition, highlighting the need for tailored monitoring and patient education.

Zoé Frayret, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan2026-10-11
📄 medicine

Integrated Metabolomics and Second-Tier Genomic Analysis for Expanded Newborn Screening of Inborn Errors of Metabolism: Protocol for a Multicentric Prospective Cohort Study in India

This protocol outlines a multicenter prospective cohort study in India designed to evaluate an integrated newborn screening approach combining LC–MS/MS metabolomics with second-tier targeted NGS to improve the early detection, diagnostic accuracy, and clinical management of inborn errors of metabolism.

Sunil Kumar Polipalli, Neerja Gupta, Seema Kapoor, Madhulika Kabra, Amit Kumar Gupta, Hem lata, Ashish Jain, Ramesh Agga (…)2026-10-11
📄 medicine

Taeniasis-cysticercosis has no borders in Sub-Saharan Africa: pig traders' knowledge, attitudes, and practices regarding Taenia solium in the cross-border pig food chain between Zambia and the Democratic Republic of Congo.

This study reveals that cross-border pig traders between Zambia and the Democratic Republic of Congo possess limited knowledge of *Taenia solium* and engage in risky practices that allow infected pigs to reach consumers, highlighting the urgent need for coordinated "One Health" strategies to control the parasite in Sub-Saharan Africa.

Alain Tshiasuma Kedi, Inge Van Damme, Sarah Gabriël2026-10-11