📄 medicine

Multicentre insights into OPAT: A comprehensive analysis of Türkiye's unstructured system 

This first multicentre study in Türkiye demonstrates that despite the absence of a standardized OPAT framework leading to higher adverse event rates and emergency department reliance, outpatient parenteral antimicrobial therapy achieves high clinical success and patient satisfaction, underscoring the urgent need for a structured, multidisciplinary system to optimize safety and resource utilization.

Elif AGÜLOĞLU BALİ, Belgin Coskun, Halime Araz, Yakup Gezer, Arzu Tarakçı, Feyza Nur Akçin Balan, Lütfiye Nilsun Altunal (…)2026-07-09
📄 medicine

Associations of Cholera Outbreaks on Adolescent Sexual and Reproductive Health Indicators in Zambia and Uganda: Evidence from Demographic and Health Surveys

This study utilizes Demographic and Health Survey data from Zambia and Uganda to demonstrate that exposure to cholera outbreaks significantly exacerbates adverse adolescent sexual and reproductive health outcomes, including increased rates of adolescent motherhood, early sexual debut, and condomless sex, highlighting the critical need to maintain SRH service continuity during public health crises.

Siyanai Zhou, Rebecca Akunzirwe, Tatenda Mugwendere, Lucie Cluver, Gibstar Makangila, Elona Toska2026-07-09
📄 medicine

DHA-enriched phosphatidylcholine alleviate lupus nephritis by regulating inflammation and the gut–kidney axis

This study demonstrates that DHA-enriched phosphatidylcholine (DHA-PC) effectively alleviates lupus nephritis in mice by suppressing renal inflammation through the NF-κB-NLRP3 pathway and restoring gut microbiota homeostasis, thereby offering superior therapeutic potential compared to conventional DHA supplementation.

Haohao Shi, Lipin Chen, Tiantian Zhang, Yuming Wang2026-07-09
📄 medicine

Clinical Characteristics, IRIS Relevance, and Prognosis of Five Major Autoimmune Diseases in HIV-Infected Patients: A 10-Year Single-Center Retrospective Cohort Study in Yunnan, China (n = 92)

This 10-year retrospective cohort study of 92 HIV-infected patients in Yunnan, China, reveals that delayed-onset immune reconstitution inflammatory syndrome (IRIS) and overlapping autoimmune syndromes frequently occur years after antiretroviral therapy initiation and independently predict poorer prognosis, underscoring the need for sustained vigilance and individualized immunosuppressive management in long-term treatment recipients.

Danqing Wang, Jiafa Liu, Yanping Liang, Sen Lin, Qiwen Zhou, Jianhua Ji, Shanshan Fan, Xi Wang, Zejiao Jiang, Haiyan Min (…)2026-07-09
📄 medicine

Knowledge, Attitude and Willingness to Perform Cardiopulmonary Resuscitation Among Medical Students in University of Ilorin: A Cross Sectional Study

This cross-sectional study of 270 medical students at the University of Ilorin reveals that while they generally hold positive attitudes toward cardiopulmonary resuscitation (CPR), significant gaps in knowledge and willingness to intervene persist, driven by barriers such as inadequate skills, fear of harm, and legal concerns, thereby highlighting the need for enhanced practical training and supportive policies.

Sarah Oreoluwa Olukorode, Olawale Taiwo Ojo-Rowland, Adejumo Oluwatobiloba Elizabeth, Morufat Gbemisola Adelagun, Adebo (…)2026-07-09
📄 medicine

Implementing and Sustaining Quality Improvement Behaviors in a Resource-Limited ICU System: A 12-Month Prospective Study

This 12-month prospective study in a Jordanian public healthcare network demonstrates that a context-sensitive educational intervention significantly improved and sustained ICU providers' confidence and engagement in quality improvement practices, despite persistent resource-related barriers.

Tamana Ebrat, Hana Abdul Rahman, Rudi Zurbuchen, Michael Wollenberg, Bashar Alzghoul, Khaldon Khader, Adel Algosous, Mim (…)2026-07-09
📄 medicine

When Warnings Wear Thin: Repeated Exposure, Habituation and the Fading Power of Pictorial Cigarette Warnings in India

This study of Indian smokers reveals that while repeated exposure to pictorial cigarette warnings accelerates habituation and emotional fading over time, the warnings retain effectiveness by driving attentional and behavioral avoidance that supports quitting, particularly when warnings are larger and rotated, though long-term smokers remain the most resistant.

Sudarshan Chanda, Samir Sarkar2026-07-09
📄 medicine

The effect of traditional and heated tobacco products on periodontal health: A cross- sectional observational study

This cross-sectional study found that while non-smokers exhibited the most favorable periodontal health, both traditional cigarette smokers and heated tobacco product users demonstrated similarly compromised periodontal parameters, including increased pocket depth, bleeding on probing, and gingival crevicular fluid volume.

Orsolya Vámos, Márta Losonczi, Laura Pál, Kata Kelemen, Tamás Demeter, Anna Földes, Gábor Varga, Péter Windisch, Brigitt (…)2026-07-09