📄 Category

medicine

14263 papers

📄 medicine

Electronic Health Record-Based Machine Learning Models for Predicting Revascularization, Amputation, and Cardiovascular Mortality in At-Risk Patients

This study demonstrates that machine learning models trained on harmonized electronic health record data from nearly 179,000 patients effectively predict revascularization and amputation with high accuracy, while showing more modest performance for cardiovascular mortality, thereby supporting the utility of EHR-based risk stratification for at-risk vascular patients.

Sydney E. Browder, Mirjami Laivuori, Tomas McIntee, Peter J. Leese, Olamide Alabi, Katharine L. McGinigle2026-10-11
📄 medicine

Fatal cut-throat injuries: a retrospective comparative autopsy study of homicidal and suicidal deaths

This retrospective comparative autopsy study of 43 fatal cut-throat injuries in Türkiye identifies specific morphological and toxicological patterns that statistically differentiate homicides from suicides, yet concludes that significant overlap necessitates an integrated assessment of autopsy, toxicology, and scene findings rather than reliance on isolated injury features for determining the manner of death.

Mehmet Doğan, Çağlar Altıntop, İsmail Çoban, Yusuf Atan2026-10-11
📄 medicine

Preoperative Machine-Learning Models for Predicting Postoperative Morbidity after Anterior Clinoidal Meningioma Surgery: Development and External Validation

This study developed and externally validated preoperative machine learning models that successfully predict medical complications, motor deficits, and cognitive decline following anterior clinoidal meningioma surgery, leading to the creation of an investigational online risk calculator.

Noa Ben Dor, Gal Ziv, Filippo Friso, Carlo Bortolotti, Diego Mazzatenta, Matteo Zoli, Matteo Martinoni, Filippo Badaloni (…)2026-10-11
📄 medicine

Association of Body Roundness Index with Cardiovascular Diseases in Middle-Aged and Older Chinese Adults with Cardiovascular-Kidney-Metabolic Syndrome Stage 0-3: Evidence from the CHARLS Study

Based on data from 7,566 middle-aged and older Chinese adults in the CHARLS study, this research demonstrates that a higher Body Roundness Index (BRI) is independently and linearly associated with an increased risk of incident cardiovascular disease in those with cardiovascular-kidney-metabolic syndrome stages 0–3, outperforming BMI and ABSI in predictive accuracy.

Ping-an Lian, Xiang Wu, Fei Xie, Shan-fu Liang, Shuais Cheng, Lei Yin, Shenwei Zhang2026-10-11
📄 medicine

Epidemiological Profile of Hypervirulent Klebsiella pneumoniae Isolates: A Multicenter Cross- sectional Study in Hebei Province, China

This multicenter cross-sectional study in Hebei Province, China, reveals that hypervirulent *Klebsiella pneumoniae* (hvKP) accounts for 25.3% of isolates, is predominantly characterized by the ST23-K1 genotype with lower antimicrobial resistance than classical strains, and primarily affects patients with respiratory or neurological disorders in ICU and respiratory departments.

MingZhi Guo, KaiYue Xu, Pu Qin, Cuixin Qiang, Jing Yang, Yanan Niu, Weigang Wang, Ye Gan, Min Zhao, Qiuyue Huo, Qianqing (…)2026-10-11
📄 medicine

Trust, place, and polysubstance use shape the feasibility of community-based drug checking in the Southern United States: A mixed-methods implementation study

This mixed-methods study in Fulton County, Georgia, reveals that while community-based drug checking is urgently needed to address the volatile drug supply, its implementation is significantly hindered by institutional mistrust, reliance on known drug sources, and the complexities of polysubstance use, indicating that legal reforms and testing tools alone are insufficient without addressing these social and contextual barriers.

Sarah Febres-Cordero, Roesheen McGilvery, Daniel J. Smith, Lydia Vlachou, Abigail (Gale) Pires, Fawaz Shanun, Nadiah Cun (…)2026-10-11
📄 medicine

The relationship between cross-reactive Plasmodium vivax antibody responses and P. knowlesi parasitaemia and clearance

This study demonstrates that pre-existing cross-reactive *Plasmodium vivax* antibodies are associated with reduced baseline *P. knowlesi* parasitaemia and slightly slower parasite clearance in Malaysian patients, suggesting a partial but complex role in influencing infection outcomes.

Jeyamalar T. Thurai Rathnam, Megha Rajasekhar, Rhea J. Longley, Anju Abraham, Timothy William, Sitti Saimah Sakam, Danie (…)2026-10-11
📄 medicine

PCR-based co-detection of respiratory bacterial pathogens among hospitalized COVID-19 patients: Early-pandemic data from Golestan Province, Iran

A retrospective study of hospitalized COVID-19 patients in Golestan Province, Iran, found that bacterial DNA from various respiratory pathogens was frequently detected via PCR in upper-airway specimens, with *Pseudomonas aeruginosa* specifically associated with severe disease, though the findings likely reflect bacterial colonization rather than active co-infection due to methodological limitations.

Ali Vaez, Hamid Jalali, Ahdieh Izanloo, Morvarid Hamrahjoo, Hadi Razavi Nikoo, Alijan Tabarraei, Abdolvahab Moradi, Sade (…)2026-10-11
📄 medicine

Endoscopic intralesional platelet-rich plasma (PRP) injection after balloon dilation for colonic Crohn's disease strictures: a pilot study

This prospective pilot study demonstrates that endoscopic intralesional platelet-rich plasma injection following balloon dilation for colonic Crohn's disease strictures is a technically feasible and safe procedure, although it did not significantly reduce restenosis rates at 3 weeks or 1 year.

Yi Lu, Tao Yang, Jing Li, Jun Deng, Wei Wang, Qianqian Ji, Huisi Mai, Zhiyin Gao, Mei Xie, Xiuqun Yuan, Lishuo Shi, Jiac (…)2026-10-11