4376 papers
This systematic review and meta-analysis of 32 studies involving over 327,000 users indicates that while diabetic ketoacidosis is an uncommon complication of Glucagon-Like Peptide-1 Receptor Agonists overall (0.7%), the risk is significantly higher in patients with type 1 diabetes (2.0%) compared to those with type 2 diabetes (0.3%).
A secondary analysis of the 2023–2024 Nigeria Demographic and Health Survey reveals that while substantial sex disparities exist in hypertension screening and diagnosis, with men significantly less likely to be detected than women, the subsequent treatment cascade shows no gender differences, indicating that Nigeria's primary challenge in hypertension management is detection rather than treatment access.
This long-term cohort study of over 5,700 individuals found that while a history of pelvic inflammatory disease significantly increases the risk of miscarriage, past Chlamydia trachomatis infection alone was not significantly associated with miscarriage, recurrent miscarriage, or preterm birth.
This systematic review evaluates exosome–liposome hybrid nanovesicles as a promising theranostic platform for breast cancer that enhances drug delivery and efficacy while identifying critical standardization and manufacturing challenges that must be addressed to enable clinical translation.
Based on a weighted analysis of the 2021 Youth Risk Behavior Survey, this study reveals that bisexual adolescents in the U.S. face a significantly higher risk of binge drinking compared to their heterosexual peers, highlighting a critical need for targeted public health interventions.
This paper assesses the readiness of the Philippines, Thailand, and Malaysia to implement pathogen genomics for antimicrobial resistance control, identifying strong foundational capabilities alongside critical gaps in data integration and governance that must be addressed to enable coordinated, high-impact surveillance and response across the ASEAN region.
This study demonstrates that novel PARG inhibitors selectively eliminate cancer cells, including non-proliferating and base excision repair-deficient populations, by inducing toxic PAR accumulation that triggers parthanatos and apoptosis independently of NAD⁺ depletion or DNA replication.
This study reveals that in Nigeria, commercial fat spreads marketed as "low-fat" paradoxically contain significantly higher sodium levels than their medium-fat counterparts, potentially undermining cardiovascular health goals by shifting consumers from fat reduction to excessive salt intake.
This community survey study reveals that financial constraints, fear of surgery, and geographical limitations are the primary barriers preventing timely eye care access, resulting in a critically low utilization rate where 68.1% of participants have never visited an eye care facility.
This retrospective study demonstrates that indocyanine green (ICG)-assisted microscopic varicocele ligation is a safe and effective short-term treatment that significantly reduces operation time and improves the precision of vascular identification compared to conventional microscopy.