📄 medicine

Dual-endoscope-assisted retrograde ureteral stenting after kidney transplantation: a case series and historical meta-analysis

This study demonstrates that a dual-endoscope-assisted retrograde technique for ureteral stenting in kidney transplant recipients achieves significantly higher first-attempt success rates (96.4%) compared to historical pooled data for conventional methods (68.4%), suggesting it is a feasible and effective solution for challenging ureteral complications despite the need for prospective multicentre validation.

Zikai Fang, Heyu Guo, Zihuan Xia, Jun Xue, Jixian Liu, Kangyu Liu, Xi Chen, Hongdi Cao, Jing Luo, Ming Gu, Qingyi Zhu, M (…)2026-10-11
📄 medicine

Impact of Cryotherapy Airflow on Neural Modulation, Pain Threshold, and Cervical Function in Upper Trapezius Myofascial Trigger Points

This study demonstrates that adding cryotherapy airflow to conventional therapeutic exercises significantly improves cervical range of motion (except right lateral flexion), reduces pain intensity and disability, and increases pressure pain threshold in patients with upper trapezius myofascial trigger points compared to exercise therapy alone.

Osama M. Abdelraheem, Wael G. Abdelnaeem, Lama Eid, Fatema H. Hassan, Thoria H. Thabet, Mahmoud Eid⁶2026-10-11
📄 medicine

Dyadic associations of psychological resilience, positive coping, and psychological distress among patients with decompensated cirrhosis and their family caregivers: a cross-sectional actor–partner interdependence model study

This cross-sectional study of 265 patient–caregiver dyads with decompensated cirrhosis reveals that psychological resilience and positive coping not only reduce individual distress but also significantly alleviate distress in their partners, highlighting the interdependent nature of psychological well-being within these relationships.

Aojie Ru, Zhiqiang Wang, Xiaotong Wan, Jianlan Chen, Yongxian Jing, Hailan Li, Jing Wang, Hui Zhang2026-10-11
📄 medicine

Prognostic Value of Prediabetes for Major Adverse Cardiovascular Events in Patients with Coronary Heart Disease: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis of 20 cohort studies involving over 63,000 patients demonstrates that prediabetes is significantly associated with an increased risk of major adverse cardiovascular events, all-cause mortality, and cardiac death in individuals with established coronary heart disease, with the magnitude of risk varying according to the specific diagnostic criteria used.

Chenyao Ding, Yawen Gao, Rod Taylor2026-10-11
📄 medicine

Dosimetric Impact of Collimator Angle and Arc Number on Target Dosimetry and Organ-at-Risk Sparing in Volumetric Modulated Arc Therapy for Thyroid-Associated Ophthalmopathy

This study demonstrates that in volumetric modulated arc therapy for thyroid-associated ophthalmopathy, a four-arc configuration with a 60°–300° collimator angle offers the optimal balance between target dosimetry and organ-at-risk sparing, while a 75°–285° angle provides the best organ protection, and 0° or 15° angles should generally be avoided.

KANG ZHANG, JINGCONG CHEN, YUHAN CHEN, LU ZOU, ZHE WANG, FENGWEI RAN2026-10-11
📄 medicine

Navigating Equity, Diversity and Inclusion in Simulation-Based Education Debriefs: A Qualitative Study of Educators’ Lived Experience

This qualitative study of 11 UK simulation educators reveals that while they frequently encounter unplanned equity, diversity, and inclusion (EDI) themes during debriefs, they often retreat from these discussions due to fears of causing harm, identity-related tensions, and a lack of specific faculty development support, highlighting an urgent need for targeted training to bridge the gap between EDI theory and practice.

Simisola Sodeinde, Hannah Maple2026-10-11
📄 medicine

Social network and ikigai are interconnected pathways to frailty, with physical activity as an independent parallel input, among community- dwelling older Japanese adults in the Kyotango longevity area

This study of community-dwelling older adults in Kyotango, Japan, demonstrates that while physical activity independently reduces frailty, social networks primarily mitigate frailty by enhancing ikigai, which serves as a critical, intervenable mediator in a parallel-pillar architecture of healthy longevity potentially linked to beneficial IL-6 signaling.

Yuji Naito, Takeshi Yasuda, Hiroaki Kitae, Katsura Mizushima, Norihiro Ouchi, Atsuo Adachi, Tadaaki Kamitani, Jin Narumo (…)2026-10-11
📄 medicine

The influence of cognitive decline on the severity and quantity of drug-drug interactions

This study of older Polish primary care patients reveals that while cognitive decline does not independently predict the risk or severity of drug-drug interactions, the daily medication count serves as the primary determinant, suggesting that structured medication reviews should be triggered by polypharmacy regardless of cognitive status.

Wojciech Timler, Minh Tuan Hoang, Joanna Kempa-Timler, Dorota Religa, Przemysław Kardas2026-10-11