📄 Category

medicine

14350 papers

📄 medicine

Endothelium-in hydrodissection (Muraine) versus endothelium-out stripping graft preparation for Descemet Membrane Endothelial Keratoplasty: a prospective two-centre cohort study

This prospective two-centre cohort study found that while the Muraine endothelium-in hydrodissection technique for DMEK offers faster graft unfolding and equivalent early visual and endothelial outcomes compared to the standard endothelium-out method, it is associated with longer dissection times, higher rates of partial tissue loss, increased 6-month endothelial cell loss, and a significantly greater need for rebubbling due to air-only tamponade.

Eduard Pedemonte-Sarrias, Antoni Salvador, José Luis Güell, Irene Sassot, Oscar Gris, José García-Arumí2026-10-11
📄 medicine

Depressive and PTSD symptoms are associated with regional differences in light-evoked brain responses in chronic ocular pain

This study reveals that individuals with chronic ocular pain who also exhibit depressive or PTSD symptoms display distinct regional differences in light-evoked brain responses compared to those without such comorbidities, suggesting that mental health status contributes to heterogeneity in central pain processing and may inform more targeted treatment strategies.

Eric Moulton, Ema Karakoleva, David Valdes-Arias, Pradip Pattany, Vanda Faria, Elizabeth Helix, Anat Galor2026-10-11
📄 medicine

Prognostic Role of HALP Score, CALLY Index, and Prognostic Nutritional Index in Polytrauma Patients Followed in the Intensive Care Unit: A Retrospective Cohort Study

In a retrospective cohort study of 162 ICU polytrauma patients, the Prognostic Nutritional Index (PNI) was identified as the only independent predictor of in-hospital mortality among the evaluated immunological and nutritional scores, outperforming both the CALLY index and HALP score.

Kadir ARSLAN, Aysun EDEHAN, Hale Cetin Arslan, Ayca Sultan Sahin2026-10-11
📄 medicine

EGFR tyrosine kinase inhibitor receipt and overall survival in metastatic non-small cell lung cancer in Egypt A retrospective descriptive cohort study

This retrospective cohort study of 99 Egyptian patients with EGFR-mutated metastatic non-small cell lung cancer found that while 73.7% received EGFR tyrosine kinase inhibitors, the resulting survival estimates are limited by heavy censoring and missing outcomes among untreated patients, preventing definitive conclusions on treatment effects or population-level access.

Esraa Jamal Moustafa Jamal, Nourin Ali Sharief, Manar Hamed Ahmed, Ahmed M. Elalfy2026-10-11
📄 medicine

A Single Arm Pilot Study to Evaluate the Safety, Feasibility, and Dose Ranging of Splenic Nerve Stimulation in Patients with Rheumatoid Arthritis Using a Novel Implantable Device

This single-arm pilot study demonstrated that laparoscopic implantation of a novel device for splenic nerve stimulation in patients with refractory rheumatoid arthritis was feasible and safe, with preliminary evidence suggesting potential reductions in disease activity and inflammatory biomarkers in some participants.

Jeroen Christiaans, Michael Reed, Neil Basu, Nigel B. Jamieson, Misha D.P. Luyer, Aysin Tulunay Virlan, Carl S. Goodyear (…)2026-10-11
📄 medicine

The STABLE Trial: Sustained Breath-Hold During Tissue Acquisition in Robotic Bronchoscopy—A Randomized Controlled Trial

The STABLE trial, a prospective randomized controlled study, found that sustained breath-hold ventilation during tissue acquisition did not improve diagnostic yield or tool-lesion positioning compared to conventional ventilation in imaging-integrated robotic bronchoscopy for peripheral pulmonary lesions.

Roshen Mathew, Olesya Danilevskaya, Sujith Cherian, Nikhil Meena2026-10-11
📄 medicine

How to improve cancer outreach programmes in rural areas: insights from a realist evaluation

This realist evaluation of the Bergo'Bus rural cancer outreach programme reveals that while a single-visit format rarely translates into sustained individual screening participation, it effectively acts as a catalyst for community mobilization and strengthens local prevention capacity through mechanisms like trust, social proof, and cross-sector bridge-building.

Zeinab El Hajj, Vincent Thevenet, Marine Narbonne, Nicolas Penel, Guilaine Wilkins, Simone Mathoulin-Pelissier2026-10-11
📄 medicine

The Role of Inhaled Corticosteroids in Preventing Hospital Attendance and Improving Clinical Outcomes in Children with Recurrent Croup: A Systematic Review

This systematic review indicates that while corticosteroids are well-established for treating acute croup, evidence supporting their use in preventing hospital attendance and improving outcomes for children with recurrent croup remains limited and primarily observational, necessitating further prospective research to define optimal treatment regimens.

Dean Robinson, Agamemnon Pericleous2026-10-11
📄 medicine

Comparative Performance of CBC-Derived Inflammatory Indices for Detecting Persistent subclinical inflammation in Children with Familial Mediterranean Fever

In a retrospective study of 182 children with Familial Mediterranean Fever, the Systemic Inflammation Response Index (SIRI) demonstrated the strongest but modest ability among CBC-derived indices to detect persistent subclinical inflammation, though disease severity remained the sole independent predictor, indicating that these indices cannot replace Serum Amyloid A testing.

Heba Abdelaty, Asmaa Elbakry, Ghada Elderiny, Walaa Shoman2026-10-11