4376 papers
This retrospective case series of four patients demonstrates that the Reper artificial iris prosthesis Model C, implanted via a three-point scleral fixation technique, is a safe and effective treatment for traumatic aniridia and aphakia, yielding significant improvements in visual function, symptom relief, and cosmetic satisfaction despite rare long-term complications.
This protocol outlines a single-center pilot randomized controlled trial in Canada designed to assess the feasibility of a larger study and explore the biological effects of a liberal versus restrictive red blood cell transfusion strategy on bleeding-related biomarkers in patients with acute leukemia undergoing induction chemotherapy.
This study demonstrates that homocysteine metabolic dysregulation drives oral submucous fibrosis through a p53-SMAD3 signaling pathway and that this pathological process can be effectively reversed by localized 5-methyltetrahydrofolate supplementation.
Carrimycin effectively ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by suppressing systemic inflammation, restoring the Th17/Treg immune balance, and reconstructing the gut microbiota composition.
This dual-cohort longitudinal study of 4,157 Chinese undergraduates reveals that dormitory peer effects significantly shape physical fitness trajectories, with dormitory clustering emerging as a stronger predictor of senior-year fitness outcomes than BMI or sex, thereby highlighting the potential of targeted dormitory interventions during the freshman-sophomore transition to combat fitness decline.
This cross-sectional study in southern Kazakhstan developed and preliminarily validated the PQoL-34 questionnaire, demonstrating its high content validity, strong internal consistency, and convergent validity as a comprehensive tool for assessing quality of life during pregnancy and family readiness for childbirth.
Using 2024 Nigeria Demographic and Health Survey data, this study found that while socioeconomic and informational factors significantly influence skilled birth attendance utilization among Nigerian women, household Water, Sanitation, and Hygiene (WASH) conditions were not significantly associated with its use after adjusting for these confounders.
This prospective cohort study in Western Kenya demonstrates that despite universal antiretroviral therapy use, maternal HIV infection remains independently associated with a significantly increased risk of low birth weight and preterm birth, a finding robustly confirmed through weighted propensity score matching and inverse probability weighting methods.
Using 2024 Nigeria Demographic and Health Survey data, this study reveals that despite the North-West having higher fertility and lower contraceptive use, the demand for modern family planning is significantly higher in the South-West, with education and the number of living children serving as common predictors across both regions while other factors vary by location.
This case report details the complex clinical course of a very preterm infant who developed *Candida albicans* sepsis and meningitis, leading to severe complications including intraventricular hemorrhage, hydrocephalus, and congenital cataract, thereby underscoring the critical need for early diagnosis and multidisciplinary management in such high-risk neonates.