📄 Category

medicine

14398 papers

📄 medicine

EGFR tyrosine kinase inhibitor receipt and overall survival in metastatic non-small cell lung cancer in Egypt A retrospective descriptive cohort study

This retrospective cohort study of 99 Egyptian patients with EGFR-mutated metastatic non-small cell lung cancer found that while 73.7% received EGFR tyrosine kinase inhibitors, the resulting survival estimates are limited by heavy censoring and missing outcomes among untreated patients, preventing definitive conclusions on treatment effects or population-level access.

Esraa Jamal Moustafa Jamal, Nourin Ali Sharief, Manar Hamed Ahmed, Ahmed M. Elalfy2026-10-11
📄 medicine

A Single Arm Pilot Study to Evaluate the Safety, Feasibility, and Dose Ranging of Splenic Nerve Stimulation in Patients with Rheumatoid Arthritis Using a Novel Implantable Device

This single-arm pilot study demonstrated that laparoscopic implantation of a novel device for splenic nerve stimulation in patients with refractory rheumatoid arthritis was feasible and safe, with preliminary evidence suggesting potential reductions in disease activity and inflammatory biomarkers in some participants.

Jeroen Christiaans, Michael Reed, Neil Basu, Nigel B. Jamieson, Misha D.P. Luyer, Aysin Tulunay Virlan, Carl S. Goodyear (…)2026-10-11
📄 medicine

The STABLE Trial: Sustained Breath-Hold During Tissue Acquisition in Robotic Bronchoscopy—A Randomized Controlled Trial

The STABLE trial, a prospective randomized controlled study, found that sustained breath-hold ventilation during tissue acquisition did not improve diagnostic yield or tool-lesion positioning compared to conventional ventilation in imaging-integrated robotic bronchoscopy for peripheral pulmonary lesions.

Roshen Mathew, Olesya Danilevskaya, Sujith Cherian, Nikhil Meena2026-10-11
📄 medicine

How to improve cancer outreach programmes in rural areas: insights from a realist evaluation

This realist evaluation of the Bergo'Bus rural cancer outreach programme reveals that while a single-visit format rarely translates into sustained individual screening participation, it effectively acts as a catalyst for community mobilization and strengthens local prevention capacity through mechanisms like trust, social proof, and cross-sector bridge-building.

Zeinab El Hajj, Vincent Thevenet, Marine Narbonne, Nicolas Penel, Guilaine Wilkins, Simone Mathoulin-Pelissier2026-10-11
📄 medicine

The Role of Inhaled Corticosteroids in Preventing Hospital Attendance and Improving Clinical Outcomes in Children with Recurrent Croup: A Systematic Review

This systematic review indicates that while corticosteroids are well-established for treating acute croup, evidence supporting their use in preventing hospital attendance and improving outcomes for children with recurrent croup remains limited and primarily observational, necessitating further prospective research to define optimal treatment regimens.

Dean Robinson, Agamemnon Pericleous2026-10-11
📄 medicine

Comparative Performance of CBC-Derived Inflammatory Indices for Detecting Persistent subclinical inflammation in Children with Familial Mediterranean Fever

In a retrospective study of 182 children with Familial Mediterranean Fever, the Systemic Inflammation Response Index (SIRI) demonstrated the strongest but modest ability among CBC-derived indices to detect persistent subclinical inflammation, though disease severity remained the sole independent predictor, indicating that these indices cannot replace Serum Amyloid A testing.

Heba Abdelaty, Asmaa Elbakry, Ghada Elderiny, Walaa Shoman2026-10-11
📄 medicine

A Nerve Root-Centered Classification System for Lumbar Disc Herniation: Development and Reliability Assessment

This study developed and validated the PUTH classification system, a nerve root-centered framework for lumbar disc herniation that demonstrated substantial-to-excellent observer reliability and high agreement between preoperative MRI and intraoperative findings in patients undergoing percutaneous endoscopic lumbar discectomy.

Longjie Wang, Zhuofu Li, Zhenhai Zhou, Lige Xiao, Yuantao Wu, Miao Li, Yong Chen, Woquan Zhong, Chuiguo Sun, Shuai Jiang (…)2026-10-11
📄 medicine

A qualitative study exploring poultry farmers’ barriers and motivations to seasonal human influenza vaccine uptake as a preventive public health measure because of avian influenza

This qualitative study of Dutch poultry farmers reveals that while many recognize the societal importance of seasonal influenza vaccination to prevent avian-human virus reassortment, uptake is hindered by government distrust, regulatory burdens, and perceived low personal risk, necessitating strategies that leverage trusted intermediaries and ensure accessible, voluntary vaccination programs.

E. J. van den Berg¹, E. Warmelink¹, T. van Loenen², K.V.C. Wevers-de Boer¹2026-10-11
📄 medicine

Impact of Opioid-sparing Anesthesia on Postoperative Quality of Recovery in Patients undergoing Laparoscopic Colorectal Resection- A Randomized Controlled Trial

This randomized controlled trial demonstrates that a multimodal opioid-sparing anesthesia strategy significantly improves postoperative quality of recovery and reduces pain and nausea compared to conventional opioid-based anesthesia in patients undergoing laparoscopic colorectal resection, although the authors note these benefits are partial and time-limited.

Conghui Hao, Yunyan Wang, Xiaobao Zhang, Pin Zhu, Yong Wu, Jiying Feng, Hengfei Luan2026-10-11