📄 medicine

Implementation of a Pragmatic Pre-Discharge Checklist to Improve Evidence-Based Transitional Heart Failure Care: A Before-and-After Cohort Study

This before-and-after cohort study demonstrates that implementing a pragmatic pre-discharge checklist significantly improved adherence to evidence-based pharmacological and non-pharmacological care processes for hospitalized heart failure patients, although no statistically significant differences were observed in mortality or readmission rates.

Raúl Eduardo Reyes-Toledo, Silvia J. Durán – Sánchez, Katherinn M. Nasner-Posso, Cristian A. Porto – Hernández, Andrés E (…)2026-07-20
📄 medicine

Androgen-related symptoms are associated with functional vulnerability in midlife men

This cross-sectional study of 329 men reveals that androgen-related symptoms, rather than bioavailable testosterone levels, are independently associated with cognitive and physical performance in midlife men, suggesting these symptoms serve as a critical indicator of functional vulnerability that complements biochemical measures.

Dan Keren, Yoel Toledano, Tzipi Strauss, Abigail Goshen, Shmuel Springer2026-07-20
📄 medicine

Histopathological Spectrum of Breast Lesions and Factors Associated with Malignancy in Mogadishu, Somalia: A Retrospective Cross-Sectional Study

This retrospective study of 522 breast specimens in Mogadishu, Somalia, reveals that while fibroadenomas are the most common diagnosis overall, increasing age and larger tumor size are independently associated with malignancy, which predominantly affects women over 35 and is primarily represented by invasive ductal carcinoma.

Mohamed Serar Yusuf, Mohamed Husein Adam, Rahma Mohamed Ali, Abdkerem Abdulahi Abdi2026-07-20
📄 medicine

Effects of Practice Testing with Corrective Feedback on Long-Term BPSD Knowledge in Dementia Caregivers: Randomized Controlled Trial

This randomized controlled trial demonstrates that a self-guided digital intervention using practice testing with detailed corrective feedback significantly improves dementia caregivers' immediate and long-term retention of knowledge regarding behavioral and psychological symptoms compared to practice testing without feedback or rereading.

Morgan D. Shumaker, Robert Ariel, Maryann Hernandez, Lesca Hadley, Sarah K. Tauber2026-07-20
📄 medicine

Psychometric analysis of the Oral Health Behavior Social Support Short Form scales (OHBSS-SF) among Mexican-American adults

This study validates the psychometric properties of the 17-item Oral Health Behavior Social Support Short Form (OHBSS-SF) scales among Mexican-American adults, demonstrating that the abbreviated tool maintains strong reliability and validity while effectively reducing respondent burden compared to the original full-length measures.

Tracy L. Finlayson, Cristian Garcia-Alcaraz, Vanessa L. Malcarne, Guadalupe X. Ayala, Kristin S. Hoeft, Mark Ryder, Stua (…)2026-07-20
📄 medicine

Comparison of DeepSeek, ChatGPT-4, and Online Medical Platforms in Addressing Chronic Pancreatitis Related Questions

This study evaluates the performance of DeepSeek and ChatGPT-4 against traditional online medical platforms in addressing chronic pancreatitis questions, finding that while these AI models offer accurate and comprehensive guideline-based information comparable to physicians, they still fall short in providing the empathetic, personalized support necessary for high patient satisfaction.

Wanshun Li, Xinyi Su, Zhicheng Yang, Zhenghui Yang, Hanbin Zhu, Chao Liu, Deyu Zhang, Haojie Huang, Zhendong Jin2026-07-20
📄 medicine

The Effect of Child Care Practices in Orphanage Homes on the Nutritional Status of Children in Nigeria

This study of 20 orphanages in Abuja, Nigeria, found that despite the provision of basic health interventions, a significant prevalence of undernutrition exists among children, with no statistically significant association observed between facility features or health practices and nutritional status, highlighting an urgent need for government support and improved monitoring.

Vivian Ngozi Onyenwere, Adaora Adeline Okechukwu, Iember Talatu Ajanaku, Andrew Patrick Fashie, Abiodun John Kareem2026-07-20
📄 medicine

A Series of Duodenal Duplication Cysts in Children 

This study reviews ten pediatric cases of duodenal duplication cysts, highlighting that abdominal pain and vomiting are the most common symptoms, ultrasound is the primary diagnostic tool with 90% accuracy, and complete surgical resection is recommended for all patients due to the risk of malignancy and potential complications like pancreatic duct connection.

Wenbo Pang, Yajun Chen, Kai Wang, Jiayu Yan, Dan Zhang, Xiumin Qin2026-07-20
📄 medicine

Dominant COSMIC Mutational Signatures and Unsupervised Machine Learning Define Mechanism-Based Therapeutic Stratification in Blast-Crisis CML: Implications in precision medicine of relapsed and refractory cancers

This study establishes a precision oncology framework for blast-crisis chronic myeloid leukemia that utilizes COSMIC mutational signatures and unsupervised machine learning to stratify patients into biologically coherent clusters, thereby enabling mechanism-based, AI-guided therapeutic prioritization for this otherwise refractory disease.

Zafar Iqbal, Abdulkareem AlGarni, Yaqob Taleb, Nasser Mohammed AlQahtani, Muhammad Farooq Sabar, Muhammad Alshuaibi, Ess (…)2026-07-20