📄 Category

medicine

13396 papers

📄 medicine

Neighborhood Vulnerability, Care Engagement, and Diabetic Retinopathy in an Underserved Urban Health System: A Retrospective Observational Study in Philadelphia

In a retrospective study of 932 adults with type 2 diabetes at an urban Philadelphia health system, multivariate analysis identified that missing clinic appointments and higher systolic blood pressure, rather than individual or community-level social determinants of health, were the significant independent predictors of diabetic retinopathy.

Savitri A. Nandula, Allison R. Casola, Ajay D. Rao, John Turella, Harris Quach, Henderer Jeffrey, Yi Zhang, Melissa Ulas2026-10-22
📄 medicine

Dying in hospital with high-grade glioma: symptom burden, end-of-life care quality, and a compressed transition to comfort-focused medication

This retrospective study of high-grade glioma patients reveals that terminal hospital admissions are characterized by severe symptom burdens, a high prevalence of impaired consciousness preventing self-reporting, and a compressed transition to comfort-focused medication, highlighting the urgent need for earlier palliative referrals and neurologically tailored anticipatory prescribing.

Roger M. Krzyżewski, Gabriela A. Brożek, Ihor Kovalchuk, Sandra A. Pilawska, Krzysztof Stachura, Borys M. Kwinta, Michał (…)2026-10-22
📄 medicine

Training insurance claim handlers in evidence-based management of whiplash-associated disorder claims: A controlled trial

A controlled trial demonstrated that Best Practice Whiplash training significantly improved Dutch insurance claim handlers' knowledge and self-efficacy regarding evidence-based whiplash management, although these gains did not translate into widespread practical implementation due to barriers such as limited contact with claimants.

Angelique M. Reitsma, Nieke A. Elbers, Arno J. Akkermans, Sandra Brouwer2026-10-22
📄 medicine

Immersive virtual reality familiarisation with the operating theatre versus verbal flip-chart education for preoperative anxiety before third molar surgery under general anesthesia: a randomized controlled trial

This randomized controlled trial found that while a brief 360-degree virtual reality familiarization significantly reduced self-reported preoperative anxiety within the intervention group, it was not superior to conventional verbal flip-chart education, and neither method altered physiological stress markers or vital signs in adults undergoing third molar surgery under general anesthesia.

Saptiadi Oktora, Harmas Yazid Yusuf, Eriska Riyanti, Firdaus Hariri2026-10-22
📄 medicine

Factors associated with partial return to work after mild traumatic brain injury

This study of 115 mild traumatic brain injury patients reveals that partial return to work is a multifactorial outcome associated with older age, intracranial lesions, extracranial injuries, severe post-concussion symptoms, and worse functional recovery, often involving adjusted working arrangements like shortened hours.

Antti Elias Huovinen, Ivan Marinkovic, Harri Isokuortti, Rahul Raj, Kaisa Mäki, Taina Nybo, Antti Korvenoja, Susanna Mel (…)2026-10-22
📄 medicine

Feline sporotrichosis in Rio de Janeiro: Space-time analysis of the main enzootic region in Brazil (1998–2018)

This ecological study analyzed 4,502 georeferenced feline sporotrichosis cases in Rio de Janeiro from 1998 to 2018, identifying significant spatiotemporal clusters in economically disadvantaged areas between 1998 and 2012 to support targeted surveillance and control strategies for this zoonosis.

Anna Barreto Fernandes Figueiredo, Mônica Avelar Figueiredo Mafra Magalhães, Daniel Cardoso Portela Câmara, Leticia Sant (…)2026-10-22
📄 medicine

Demographics, Therapeutic Efficacy, and Comorbid Burden in Pityriasis Rubra Pilaris: Insights from a Retrospective Cohort

This retrospective cohort study of 74 patients at Oregon Health & Science University characterizes the demographics, treatment outcomes, and comorbid burden of pityriasis rubra pilaris, revealing that biologic therapies (particularly IL-17 and IL-23 inhibitors) demonstrate superior efficacy in adult patients compared to traditional oral agents, while highlighting a high prevalence of metabolic and psychiatric comorbidities.

Alexandre Couto e Silva, Heejo Keum, Amirali Veshagh, Teri M. Greiling2026-10-22
📄 medicine

Individual Cardiometabolic Risk Factors and Long-Term Cardiovascular Outcomes in Metabolic Dysfunction-Associated Steatotic Liver Disease

In a retrospective study of nearly 3,000 patients with metabolic dysfunction-associated steatotic liver disease (MASLD), diabetes mellitus and low high-density lipoprotein cholesterol were identified as the only independent cardiometabolic risk factors significantly associated with long-term major adverse cardiac and cerebrovascular events, suggesting that the specific type and combination of risk factors offer superior prognostic value compared to the total count of risk factors alone.

Naoki Shibata, Yasuhiro Morita, Takanori Ito, Yasunori Kanzaki, Naoki Watanabe, Naoki Yoshioka, Yoshihito Arao, Hiroyuki (…)2026-10-22
📄 medicine

Second-generation epidermal growth factor receptor-tyrosine kinase inhibitors as a potentially cost-effective salvage option following third-generation resistance in patients with uncharacterized mechanisms: a retrospective propensity-matched analysis

This retrospective propensity-matched analysis suggests that switching to second-generation EGFR-TKIs, particularly dacomitinib, after third-generation resistance in EGFR-mutated NSCLC patients with unknown mechanisms yields a higher objective response rate without compromising survival, potentially offering a cost-effective salvage option despite the lack of a definitive survival benefit.

Cuicui Zhang, Zhen HE, Xiance TANG, Xiaojing YANG, Sen YANG, Shuxiang MA, Yuqing MO, Yufeng WU, Haiyang CHEN, Peng LI, Y (…)2026-10-22