📄 medicine

Altered action-related modulation of visual size perception in schizophrenia: Associations with avolition and exploratory effects of supramarginal gyrus stimulation

This study demonstrates that individuals with schizophrenia exhibit altered action-related modulation of visual size perception compared to healthy controls, a deficit that correlates with avolition and is preliminarily linked to the function of the left supramarginal gyrus.

Jian Xu, Jixue Bao, Yi Zhang, Shen Zhang, Jin Chen, Xiaoxuan Liu, Xiaojian Jia2026-10-22
📄 medicine

A multimodal CT-based machine-learning model for differentiating pulmonary sarcomatoid carcinoma from conventional non-small cell lung cancer: an internally validated study

This internally validated study demonstrates that a multimodal machine-learning model integrating clinical data and CT radiomics, particularly intratumoral low-attenuation areas, effectively differentiates pulmonary sarcomatoid carcinoma from conventional non-small cell lung cancer, though the findings remain exploratory due to potential acquisition heterogeneity and the lack of external validation.

Zhihong Chen, Wenjian Tang, Jiawei Feng, Yuan Kang, Yujin Yin, Qing Chen, Zhongjian Liao, Xingting Qiu, Ming Jia, Jianpi (…)2026-10-22
📄 medicine

Milestone Events in Atypical Parkinsonian Syndromes: A Preliminary Observation

This preliminary retrospective study of 19 patients suggests that while recurrent falls and walking assistance are common early milestones in PSP and MSA respectively, DLB may be characterized by a distinct pattern where multiple functional milestones cluster around three years post-onset, highlighting the need for larger prospective studies to validate these subtype-specific trajectories.

Lvming Zhang, Jilai Li, Jichen Du, Zhirong Wan2026-10-22
📄 medicine

Predicting therapeutic neurosurgical intervention within 7 days after initial nonoperative management of mild traumatic brain injury with subdural hematoma: development and internal validation of a clinical-radiographic model

This study developed and internally validated a clinical-radiographic model using admission data to predict the likelihood of therapeutic neurosurgical intervention within 7 days for adults with mild traumatic brain injury and subdural hematoma initially managed nonoperatively, demonstrating strong predictive accuracy while emphasizing its utility for surveillance prioritization rather than defining operative indications.

Po-Hsin Lin, Zhuo-Hao Liu, Ching-Chang Chen, Yi-Ting Chen, Chun-Ting Chen, Ting-Wei Chang, Yu-Chi Wang, Shuo-Chi Chien2026-10-22
📄 medicine

Predicting high-risk HPV infection and genotype co-infection using genital tract microecological and pathogen characteristics: a machine learning study

This retrospective study of 3,403 patients demonstrates that vaginal microecological dysbiosis and specific genital tract infections are independent predictors of high-risk HPV positivity, with a Random Forest model achieving moderate discrimination and an Ensemble Classifier Chains approach improving multi-genotype co-infection prediction.

Jiaoling Wen, Huisan Xiao, Guoxuan Li, Zhe Lu, Xiangyue Zeng, Ying Zheng2026-10-22
📄 medicine

Coagulation Trajectory Subphenotypes Identify High-Risk Sepsis Patients Missed by the Sepsis-Induced Coagulopathy Score: A Retrospective Cohort Study with External Validation

This retrospective cohort study demonstrates that analyzing 72-hour trajectories of routine coagulation markers identifies a high-mortality sepsis subphenotype missed by the static Sepsis-Induced Coagulopathy (SIC) score in over 80% of cases, a finding validated in an external dataset.

Xueshu Yu, Wen Xu, Yincai Ye, Luwei Xu, Jingye Pan2026-10-22
📄 medicine

Ulcer Exclusion with Intraluminal Isolation Combined with Distal Gastrectomy for Refractory Bleeding from Suprapapillary Duodenal Ulcers: A Report of 26 Cases

This study reports that Ulcer Exclusion with Intraluminal Isolation Combined with Distal Gastrectomy (UEIICDG) is a safe and effective surgical alternative for managing refractory bleeding from suprapapillary duodenal ulcers, demonstrating durable hemostasis and minimal postoperative complications in a cohort of 26 patients.

Xianyan LIU, Chuiye ZENG, Bo WEN, Junjie ZHU, Yang PENG, Sheng LI2026-10-22
📄 medicine

Combined ovarian tissue cryopreservation and in vitro maturation of ovarian- tissue oocytes (OTO-IVM) for emergency fertility preservation in the early postpartum period: a case report and systematic review of the literature

This case report and systematic review describe the first attempt at combined ovarian tissue cryopreservation and in vitro maturation for emergency fertility preservation in a lactating postpartum patient, which resulted in failed oocyte retrieval and maturation despite adequate follicular growth, thereby highlighting the unique challenges of the postpartum ovary and the continued reliance on tissue cryopreservation.

Roza Berkovitz-Shperling, Shai Trigerman, Yael Kalma, Hadar Feder, Benny Almog, Yoni Cohen, Adiel Kahana2026-10-22
📄 medicine

Improving Oral Health, Identification and Care in the Dental Setting of Patients Experiencing Domestic Abuse: A Scoping Review

This scoping review of 17 studies finds that while educational and practice-based interventions effectively improve dental professionals' knowledge and confidence in identifying and responding to domestic abuse, evidence regarding their actual impact on clinical practice and patient outcomes remains limited due to systemic barriers and a lack of robust research.

Simon Moore, Lucy Gladdis, Anna Sydor2026-10-22
📄 medicine

Impact of atrial fibrillation on hemodynamics in a sheep model of the Fontan circulation

In a sheep model of the Fontan circulation, the onset of atrial fibrillation significantly impairs hemodynamics by reducing cardiac output by 30% and elevating central venous pressure, highlighting the critical contribution of atrial contraction to overall circulation in Fontan physiology.

Megan M. McKittrick, Yoshio Otaki, Ashok Muralidaran, Sonnet S. Jonker, Samantha Louey, Andrew Giustini, Sarah M. Alaniz (…)2026-10-22