📄 Category

medicine

3171 papers

📄 medicine

Distinct Mortality Risk Patterns of TyG- ABSI and TyG-BMI in Older Adults With Type 2 Diabetes: A Community-Based Cohort Study

In a community-based cohort of 54,973 older adults with type 2 diabetes, this study found that while both the TyG-ABSI and standalone TyG indices showed strong positive associations with all-cause and cardiovascular mortality, the TyG-BMI index exhibited a distinct U-shaped relationship, highlighting the superior predictive value of TyG-ABSI and the need for caution when using BMI-based derivatives in geriatric diabetic populations.

Wenze Hu, Canyan Huang, Juan Dai, Yuanyuan Zhao, Leqi Wang, Yaqiong Yan, Qing Liu2026-07-20
📄 medicine

Clinical Characteristics and Outcomes of Adult Patients Presenting to the Emergency Department After Hanging: An Eight-Year Retrospective Study

This eight-year retrospective study of 99 adult emergency department patients with hanging injuries identifies cardiac arrest on presentation, complete suspension, severe neurological impairment, metabolic derangement, and cerebral edema as key factors associated with in-hospital mortality, highlighting their potential utility for early risk stratification.

Ahmet Burak Urfalioglu, Mustafa Oguz Tugcan, Akkan Avci2026-07-20
📄 medicine

Effect of Roxadustat on Microinflammatory Status in Patients with Chronic Kidney Disease

This study demonstrates that roxadustat alleviates microinflammation in patients with chronic kidney disease by modulating the metabolism-inflammation axis, specifically by reversing cyclopentolate-induced inflammatory responses in renal tubular epithelial cells and significantly reducing serum levels of key inflammatory factors.

Ying Xu, Yixi Ke, Jinyi Guo, Yichen Xiao, Zhen Wang, Baochun Guo, Hualin Ma2026-07-20
📄 medicine

Prevalence and Association of Adverse Childhood Experiences among People with Substance Use Disorder in Thailand

This study reveals that adverse childhood experiences are highly prevalent among people with substance use disorder in Thailand and are significantly associated with high-risk polysubstance, depressant, and cannabis use, highlighting the urgent need for trauma-informed drug policies in the region.

Pimarnpol Siriwongwan-ngarm, Wichuda Jiraporncharoen, Chaisiri Angkurawaranon, Patcharin Pingmuangkaew, Unyanee Kitiruan (…)2026-07-20
📄 medicine

Early Plasma Cytokine Profiling Refines Relapse Risk Beyond Interim Pet/Ct in Classical Hodgkin Lymphoma

This study demonstrates that early plasma cytokine profiling, particularly dynamic changes in IL-6 and a composite score of IL-7 and Basic FGF, provides significant prognostic value for relapse risk in classical Hodgkin lymphoma that refines and complements interim PET/CT response, even among patients achieving a complete metabolic response.

Laura Gálvez-Carvajal, Jesús Velasco-Suelto, Silvia Sequero-López, Marcos Melián-Sosa, Natividad Martínez-Banaclocha, Ma (…)2026-07-20
📄 medicine

Neuroactive Medication Exposure Across Neonatal Intensive Care Units of a Large, Multistate Healthcare System

This retrospective cohort study of nearly 17,000 NICU infants reveals that neuroactive medication exposure is most prevalent among premature and White infants, with usage patterns shifting over six years toward increased use of agents like dexmedetomidine and fentanyl while decreasing reliance on benzodiazepines and barbiturates.

Daley Owens, Timothy Bahr, Ariel Tarrell, Brian Winther, Tara Dupont, Jared Olson, Shelley Lawerence2026-07-20
📄 medicine

Effects of Comprehensive Chest Physiotherapy on Early Peripheral Blood Th17/Treg Immune Balance and Its Association with Key Clinical Outcomes in Postoperative Patients Receiving Mechanical Ventilation in the Surgical Intensive Care Unit: A Prospective, Single-Blind, Randomized Controlled Trial

This prospective, single-blind, randomized controlled trial demonstrates that comprehensive chest physiotherapy in postoperative mechanically ventilated patients significantly suppresses STAT3 signaling, promotes Th17/Treg immune balance restoration, and substantially reduces mechanical ventilation duration and ICU length of stay.

zheng luo, sheng tang, Yang Yang, Yunjing Hou, Yue Wang, Xueling Ren, Keke Kang, Guiying Wu, Yan Gao, Hongying Pi, Hongj (…)2026-07-20
📄 medicine

An Injectable Self-Healing Alginate–Gelatin Hydrogel Incorporating Ag-based Metal-Organic Framework and Diclofenac as Sustained Anti-bacterial and Anti-Inflammatory Therapy for Potential Osteochondral Repair

This study presents an injectable, self-healing alginate–gelatin hydrogel reinforced with in-situ formed Ag-based metal-organic framework nanoparticles for the sustained co-delivery of diclofenac, offering a multifunctional therapeutic strategy that simultaneously combats infection, mitigates inflammation, and promotes osteochondral repair while minimizing systemic toxicity.

Amin Hashemi Aghdam, Reza Mohammadi2026-07-20
📄 medicine

Quantifying service pressure in the public oral health system in India and its implications for curative care and public health dentistry

This paper introduces a Service Pressure Index (SPI) to quantify the significant gap between required and available clinical capacity in India's public oral health system, revealing that high service pressure forces a shift toward symptomatic care and highlighting the critical need for preventive strategies and system strengthening to ensure effective service delivery.

SRINIVAS PACHAVA, HARSHA VARDHAN REDDY NANDYALA, KAVYA SRAVANI JAMMALAMADAKA, UJWALA KUKKALA, SRUJANA BHASHYAM, RAJA SEK (…)2026-07-20