📄 medicine

Changes in Lower Incisor–Related Soft-Tissue Aesthetic Indices During a 2–4-Year Orthodontic–Orthognathic Treatment Course in Skeletal Class III Patients: PAOO-Assisted Versus Conventional Orthodontics

In skeletal Class III patients undergoing combined orthodontic–orthognathic treatment, the addition of periodontally accelerated osteogenic orthodontics (PAOO) significantly improves periodontal phenotype and reduces the hazard of mandibular incisor labial gingival recession compared to conventional orthodontics, although it does not markedly enhance interdental aesthetic outcomes.

Jian Liu, Yi Li, Xiaotong Li, Xiaoxia Wang, Li Xu, Jianxia Hou2026-07-20
📄 medicine

The Emotional Burden of HIV: A Systematic Review of Affective Outcomes in HIV-Positive Populations (2020–2025)

This systematic review of 95 studies from 2020 to 2025 reveals that depression and anxiety are highly prevalent among people living with HIV, driven largely by stigma, and underscores the critical need to integrate routine mental health screening, psychological interventions, and stigma-reduction strategies into HIV care to improve emotional well-being and treatment adherence.

Mohd Annas Shafiq Ayob, Azhar Abdul Aziz, Faridah Mohd Sairi, Noor Syahida Md, Mohd Norazri Mohamad Zaini2026-07-20
📄 medicine

Behavioral Risk factors for Non-Communicable Diseases in mentally ill patients at Tertiary hospital Koshi province

This cross-sectional study of 322 patients at Koshi Hospital in Nepal reveals a high prevalence of behavioral risk factors (such as tobacco use, alcohol consumption, and physical inactivity) and metabolic comorbidities (including hypertension, diabetes, and obesity) among mentally ill individuals, underscoring the urgent need for integrated screening and prevention strategies for non-communicable diseases in this vulnerable population.

Bhumika Rai, Sharada Kunwor, Punam Kumari Mandal, Sachin Nepali, Tulasa Dahal2026-07-20
📄 medicine

Joint associations of the triglyceride–HDL cholesterol–glucose–body mass index composite index and C-reactive protein with incident cardiometabolic multimorbidity in older Chinese adults: a nationwide prospective cohort study

In a nationwide prospective cohort study of older Chinese adults, the triglyceride–HDL cholesterol–glucose–body mass index composite index (TyHGB) was found to be a robust independent predictor of incident cardiometabolic multimorbidity, while C-reactive protein (CRP) offered weaker independent risk information, though their joint classification effectively helped stratify risk gradients.

Zichuan Yu, Ning Yin, Hao Zhang, Xinyue Zhang, Tian Zhou, Jialong Niu, Hainan Yang, Aakrist Krishna Karmacharya, Qian Fa (…)2026-07-20
📄 medicine

Sleep Quality and Cardiometabolic Risk Markers Among Clinical Health Professions Students in South western Uganda, A Cross-Sectional Study

This cross-sectional study of 429 clinical health professions students in southwestern Uganda reveals that poor sleep quality is highly prevalent (71.6%) and significantly associated with low physical activity, elevated blood pressure, and central obesity, highlighting the need for integrated wellness interventions.

Conrad Lubwama, Dauglas Nkoyooyo, Derrick Asiimwe, Ronald Ouma Omolo, Stuart Agaba, Marie Curie Nakaddu, Allan Mugisha O (…)2026-07-18
📄 medicine

Cultural Competence, Patient-Centred Care, and Perioperative Nursing: A Scoping Review of Global, African, and Ghanaian Evidence

This scoping review of 30 global studies highlights a critical lack of perioperative-specific, patient-centered, and African evidence on cultural competence in nursing, thereby establishing the urgent need for context-specific research and interventions within Ghanaian surgical care settings.

Ivana Abena Adzigbli, Adzo Atswei Kwashie, Anita Asiwome Adzo Baku, Theresa Barnes, Adelaide Maria Ansah Ofei2026-07-18
📄 medicine

Comparison of Different Keratometric Values in Patients Requiring Intraocular Lens Implantation After Keratoplasty

This retrospective study of 24 post-keratoplasty patients found that while no statistically significant differences existed among autorefractor, topographic, and Holladay EKR keratometric methods for IOL power calculation, autorefractor and topographic measurements demonstrated greater consistency and lower variability than EKR.

Binhan Aslan Akbulut, Burcu Kasım Tekdemir, Miray Faiz Turan, Yusuf Koçluk2026-07-18
📄 medicine

Dietary Patterns in relation to anthropometric indices Among Children Aged 6–23 Months in an Informal Settlement, South-East Pretoria

This cross-sectional study of 93 children aged 6–23 months in a Pretoria informal settlement identified seven distinct dietary patterns and found that while dietary diversity was moderate, high stunting rates persisted, with a notable negative association between reliance on legumes and nuts and height-for-age z-scores, suggesting that such dietary choices reflect resource constraints rather than optimal nutrition.

TF Thindisa, P Tshiambara, TR Mudau2026-07-18
📄 medicine

Knowledge, Attitudes and Engagement in Preventive Care Practices Towards Diabetes and Hypertension Among Women in Tanzania: A Community Based- Study

A community-based study of 301 women in Kilimanjaro, Tanzania, reveals that while health-seeking behaviors are common, knowledge of diabetes and hypertension is poor and sustained preventive lifestyle practices are infrequent, with asset ownership identified as the sole independent predictor of engagement in preventive care, suggesting a need for interventions that address financial barriers and structural access rather than relying solely on health education.

Sanjura Biswaro, Rehema Ahmed Mavura, Ashraf Mahmoud, Fatuma Mohamed Nuru, Kilian Ernest Mruma, Florida Muro2026-07-18
📄 medicine

Identifying Biomarkers for Early Prediction of Coronary Artery Lesions and Intravenous Immunoglobulin Non-response in Kawasaki Disease Based on Urine Multi-omics Analysis

This study utilizes integrated urine metabolomic and proteomic profiling to identify specific purine metabolism-related biomarkers, such as APRT, PNP, HPRT1, and guanosine, for predicting coronary artery lesions and guanine for detecting IVIG non-response in Kawasaki disease patients.

Xiangfan Zeng, Peng Yu, Manying Shi, Junkai Duan, Jiyi Huang2026-07-18