13396 papers
This case report describes a rare instance of primary cutaneous T-cell lymphoma developing in a postoperative GIST patient following combined imatinib and sintilimab therapy, highlighting the utility of multimodal non-invasive skin imaging as an early diagnostic aid while emphasizing the necessity of histopathological confirmation.
This study of six Chinese provinces from 2005 to 2020 reveals that while temperature acts as a strong, threshold-shaped driver of Japanese encephalitis with sensitivity increasing by latitude, its effect is uniform across age groups, indicating that the observed shift from pediatric to adult cases is driven by cohort immunity rather than age-specific climate sensitivity.
This case report describes a 77-year-old female with multifocal small intestinal neuroendocrine tumors who experienced diagnostic delays due to missed biomarker screening, underwent complex surgical resections revealing discordant findings between advanced imaging and final pathology, and ultimately highlights the critical need for early biomarker utilization in patients with unexplained gastrointestinal symptoms.
This retrospective study of deceased-donor kidney transplants in Sri Lanka found that while higher HLA mismatch burden significantly increases the risk of acute rejection and reduces rejection-free survival, it does not independently predict graft or patient survival, which are primarily driven by infection and recipient factors such as age and diabetes.
This study analyzes 2025 MICS data to reveal a strikingly high prevalence of Caesarean section deliveries in Bangladesh (72.75%), characterized by significant geographic disparities and strong associations with wealth, residence, maternal age, parity, and antenatal care utilization, underscoring the urgent need for monitoring and promoting clinically appropriate childbirth practices.
This retrospective CBCT study of 12,874 teeth found a 0.05% prevalence of enamel pearls, which were significantly associated with molar tooth type and number but not gender, and notably showed no co-occurrence with supernumerary teeth.
This systematic review of over 40,000 university students across diverse global regions concludes that problematic social media use significantly impairs sleep quality by disrupting circadian rhythms and suppressing melatonin, thereby necessitating urgent multi-sectoral interventions to protect student well-being.
This cross-sectional study of 1,500 preschool children in Rupandehi, Nepal, reveals a high prevalence of dental caries (52.7%) and significant treatment needs, with school type and oral hygiene status identified as the strongest associated risk factors.
In a comparative cohort study of patients hospitalized with acute decompensated heart failure, a point-of-care ultrasound–guided early decongestion strategy was not associated with improved 6-month outcomes of death or heart failure readmission compared to standard care.
This retrospective study of 81 chronic HBV patients suggests that while serum CHI3L1 is positively associated with significant liver fibrosis and improves diagnostic models, the findings remain exploratory due to inconsistent validation results in a small cohort and require further rigorous testing before clinical application.