📄 medicine

Prevalence, trends, and correlates of long COVID in mainland China after the policy shift: findings from two cross-sectional surveys

Based on two cross-sectional surveys of over 47,000 participants in mainland China, this study reveals that while long COVID prevalence declined from 52.34% following the 2022 Omicron wave, it remains a significant health challenge strongly associated with specific demographic, health, and lifestyle factors, underscoring the need for targeted community interventions and integrated primary care management.

Xiaoli Ruan, Yang Yuan, Yujie Wang, Yujing Zhang, Jinfeng Li, Jie Liu, Zechen Zhang, Xiao Zhang, Zhiwei Li, Xiaolin Zhan (…)2026-07-17
📄 medicine

Renal function impairment and associated factors among adult HIV-positive patients attending anti-retroviral therapy clinics in Ethiopia

This multi-center cross-sectional study conducted in Ethiopia from May to July 2025 found that 12.3% of adult HIV-positive patients on antiretroviral therapy experienced renal function impairment, which was significantly associated with hypertension, diabetes mellitus, cigarette smoking, and the use of non-TDF-based ART regimens.

Henock Semaw Tegegne, Belayneh Lulseged, Fanuel Alemayehu Tefera, Seman K Ousman2026-07-17
📄 medicine

Prolonged travel time to intensive care in Colombia: a national analysis to inform critical care policy and network design

This national geospatial analysis reveals that while Colombia has expanded ICU capacity, significant geographic disparities persist in travel-time access to critical care—particularly for neonatal, pediatric, and burn services—highlighting the need for targeted network optimization and expansion in underserved areas.

Agamenón Quintero Villarreal, Joseph L. Nates, Francisco Camargo-Assis, Juan José Ramírez Melo, Juan C. Lyons, David F. (…)2026-07-17
📄 medicine

Escalated single Platelet Inhibition for one month plus Direct oral anticoagulation in patients with Atrial fibrillation and acUte coRonary syndrome undergoing percutaneoUS coronary intervention (EPIDAURUS): A randomized-controlled trial

The EPIDAURUS randomized-controlled trial was prematurely terminated due to safety concerns, revealing that adding potent P2Y12-inhibitors (prasugrel or ticagrelor) to direct oral anticoagulants in patients with atrial fibrillation and acute coronary syndrome significantly increased bleeding risks without providing a clear reduction in ischemic events compared to a clopidogrel-based regimen.

Konstantinos Rizas, Konstantinos Mourouzis, Dominik Rath, Christoph Olivier, Laura Villegas Sierra, Theofanis Korovesis (…)2026-07-17
📄 medicine

Arjunetin as a promising phytotherapeutic molecule: Isolation from Terminalia arjuna bark and therapeutic evaluation for anti-inflammatory, anti-cancer, anti-diabetic, and cytotoxic activities

This study validates the therapeutic potential of *Terminalia arjuna* by developing a novel method to isolate high-purity arjunetin and demonstrating its significant anti-inflammatory, anti-diabetic, and anti-cancer activities alongside the efficacy of the direct ethanolic extract.

Gandarvakottai Senthilkumar Arumugam, Sathyanarayana N Gummadi2026-07-17
📄 medicine

Selective Preservation of the Apical Pulp During Surgical Management of Perforating Internal Root Resorption: A Case Report with 1-Year CBCT Follow-up

This case report demonstrates that selective preservation of healthy apical pulp tissue during surgical management of perforating internal root resorption can lead to successful healing and bony repair at one-year follow-up, offering a potential alternative to conventional complete pulpectomy in carefully selected cases.

Saeed Asgary2026-07-17
📄 medicine

Microbiological Contamination and Its Association with Physicochemical Parameters in Artisanal Gold Mining Areas of Siguiri, Guinea

A study of water sources in the Siguiri artisanal gold mining area of Guinea reveals that river water is significantly more microbiologically contaminated than borehole water, with turbidity identified as a strong positive predictor of microbial levels, underscoring the urgent need for integrated monitoring and point-of-use treatment.

Aly Badara TOURE, Mariama Sadjo DIALLO, Maladho DIABY, Kadio Jean Jacques Olivier KADIO, Soriba CAMARA, Djiba KABA, Said (…)2026-07-17
📄 medicine

Mental Health Challenges and Substance Use Among Adolescents in a Family Medicine Clinic in a Nigerian Tertiary Hospital: A Cross-sectional Study

This cross-sectional study of 385 adolescents in a Nigerian tertiary hospital found that 24.7% experienced mental health challenges or substance use risk, with at-risk substance use being the strongest predictor of mental health issues, underscoring the need for routine screening and context-specific, family-focused interventions in primary care settings.

Roseline Egbe Adah, Erhuvwu Vivian Isenalumhe, Ekinandoese Margaret Emankhu2026-07-17
📄 medicine

Equality of Poor Outcomes in Laryngotracheal Stenosis: A 20-Year South African Study

This 20-year South African study reveals that in a resource-constrained setting, universal health-system delays and socioeconomic factors did not create outcome disparities for laryngotracheal stenosis patients because system-wide constraints led to an "equality of poor outcomes," where clinical success was instead determined primarily by disease aetiology and comorbidities rather than diagnostic or treatment delays.

Gerhard Johan Klopper, Lufunda Lukama, Oladele Vincent Adeniyi2026-07-17