📄 Category

medicine

13396 papers

📄 medicine

Post-transfusion Haemoglobin Increment Following Packed Red Blood Cell Transfusion and Associated factors Among Children With Sickle Cell Anemia At Tertiary hospital in Tanzania: A Retrospective Observational Study

This retrospective study of 100 Tanzanian children with sickle cell anemia found that a 10 mL/kg packed red blood cell transfusion resulted in a mean hemoglobin increment of 2.86 g/dL, which was significantly negatively correlated with pre-transfusion hemoglobin levels but not with age or body weight.

Hamis Mnyelema, Adam Chai, Anna Makoba, Yusuph Kilanga, Mwinyi Shawwaly Omary2026-10-21
📄 medicine

Age and oxygen saturation predict cognitive performance in covid- 19 survivors at least two months after discharge

In a study of 159 COVID-19 survivors assessed at least two months post-discharge, researchers found that older age and lower oxygen saturation during physical exertion are significant predictors of reduced cognitive performance, with the negative impact of low oxygen levels on cognition being more pronounced in older individuals.

George Vavougios, Dimitrios Mysiris, Vasileios Stavrou, Nico Biagi, Kyriaki Astara, Eleanna Pitaraki, Stylianos Boutlas (…)2026-10-21
📄 medicine

Surgical Decompression of the Deep Motor Branch of the Ulnar Nerve After Fifth Metacarpal Fracture: Technique, Indications and Pitfalls

This paper describes a surgical technique for decompressing the deep motor branch of the ulnar nerve following fifth metacarpal fractures, highlighting its indications, procedural details, and the successful restoration of hand function in patients with delayed motor deficits.

Francesco Zanchetta, Giorgio Eugenio Pajardi, Stephanie Hili, Elisa Maria Ragaini, Luigi Troisi2026-10-21
📄 medicine

A Tissue-Targeted Vaccine Protects Against Recurrent Ocular Herpes Infection and Disease, and Alleviates the Associated Cognitive, Behavioral, and Social Deficits in a 'Humanized' HLA Transgenic Mouse Model of UVB-Induced Reactivation

A novel prime/pull/keep T-cell vaccine utilizing a topical AAV8 vector, chemokine, and cytokines successfully protects humanized HLA-transgenic mice against recurrent ocular herpes and its associated neurobehavioral deficits by inducing durable, polyfunctional tissue-resident T cells at sites of viral latency and reactivation.

Sweta Karan, Swayam Prakash, Aziz A. Chentoufi, Khan Intharachalit, Sarah Xue Le Ng, Junseong Hwang, Chhaya Maurya, Lbac (…)2026-10-21
📄 medicine

Healthcare workers’ acceptance of drone-based vaccine delivery and associated factors at rural health posts in Rwanda: a cross-sectional study using a census approach

This cross-sectional census study of rural health posts in Rwanda found that vaccination focal persons reported high acceptance of drone-based vaccine delivery, a sentiment significantly driven by perceived speed benefits and ease of use, despite lingering concerns regarding operational safety and vaccine integrity.

Etienne Numviyumukiza, Gislain Ineza, Olivier Niyonkuru, Florence Haruna, Pedro Kremer2026-10-21
📄 medicine

A Community-Based Intervention to Increase HIV Pre-Exposure Prophylaxis Use among Individuals Receiving Re-Entry Services: Results from a Formative Evaluation

A formative evaluation of a community-based re-entry program in Dallas, Texas, revealed that while criminal-legal individuals face significant barriers like low perceived risk and mistrust, they remain open to PrEP discussions when interventions address social needs, correct misconceptions, and utilize culturally competent, non-judgmental messaging.

Robin T Higashi, Timothy P Hogan, Sophie Gao, Christina Melton Crain, Laura Hansen, Zoe Pulitzer, Mason Parri, Clare Cha (…)2026-10-21
📄 medicine

Antiangiogenic Class and Trial Population Are Confounded in First- Line Immunotherapy for Hepatocellular Carcinoma: A Bayesian Network Meta-Analysis of Nine Randomised Trials

This Bayesian network meta-analysis of nine trials reveals that the apparent superiority of anti-VEGF antibody-based regimens over TKI-based regimens in first-line hepatocellular carcinoma treatment is unidentifiable as a true drug-class effect due to severe confounding by trial population characteristics (specifically hepatitis B prevalence and geographic enrollment), rendering class-level rankings unreliable without individual patient data or head-to-head comparisons.

Burkhoniddin Tillashaykhov, Iroda Ikromova, Dilnavoz Berdiyeva2026-10-21
📄 medicine

Rainfall and human activities drive Aedes aegypti breeding sites infestation and larval density in urban and rural settings of Bobo-Dioulasso in western Burkina Faso

A cross-sectional study in Bobo-Dioulasso, Burkina Faso, reveals that *Aedes aegypti* infestation and larval density are driven by the interplay of rainfall patterns and human practices, with specific container types like terracotta jars, barrels, and tires serving as the primary production sites despite seasonal variations.

Soumanaba Zongo, Zouéra Laouali, Aboubacar Karabinta, Abdoul A. Millogo, Ali Ouari, Thérèse S. Kagoné, Hyacinthe K. Toe (…)2026-10-21