📄 medicine

Early Serum Interleukin-6 Discriminates Meconium Aspiration Syndrome in Symptomatic Term Infants Born Through Meconium-Stained Amniotic Fluid

This study demonstrates that early serum interleukin-6 levels measured within the first 6 hours of life serve as a highly accurate biomarker for distinguishing meconium aspiration syndrome from other respiratory symptoms in term infants born through meconium-stained amniotic fluid, provided they do not have chorioamnionitis or severe perinatal asphyxia.

Nashwa Farouk Mohamed, Osama Aboalfotoh Elfeky, Dina Saad Abdelmotaleb, Mostafa Saeed Abdelhamed Zidan2026-07-16
📄 medicine

Association Between Routine Childhood Immunization Coverage and Under-Five Mortality in Sub-Saharan Africa: An Ecological Panel Study, 2000–2024

This ecological panel study of 49 sub-Saharan African countries from 2000 to 2024 demonstrates that higher routine childhood immunization coverage, particularly for DTP3, is significantly associated with reduced under-five mortality, supporting the continued prioritization of vaccination within integrated child-survival strategies.

Henry Muhumuza2026-07-16
📄 medicine

Impaired Platelet Recovery Is Associated with Mortality after Severe Neonatal Intraventricular Hemorrhage Brief Report

This study demonstrates that impaired longitudinal platelet recovery, rather than a single platelet count, is significantly associated with increased mortality in infants with severe neonatal intraventricular hemorrhage, suggesting that platelet trajectory may serve as a valuable prognostic indicator.

Michael Lance Christian, Garrett Gianneschi, Onajovwe Fofah2026-07-16
📄 medicine

“There Needs To Be More People Sharing That Information Across the Nation”: Opportunities to Promote HIV Pre-Exposure Prophylaxis Awareness and Uptake among People Releasing from Jail or Prison

This study of individuals released from Washington State jails and prisons reveals that while many perceive themselves at risk for HIV, low PrEP uptake is driven by structural barriers and a need for greater awareness, suggesting that effective prevention strategies must prioritize education and low-barrier access both during and after incarceration.

Susan M. Graham, Helene Starks, Emily J. Callen, Eamonn J. McGonigle, Gina Liu, Zoe Senter, Keonna Moffett, Winter Forsy (…)2026-07-16
📄 medicine

Geographic Inequities and Temporal Trends in Preterm Births in Ecuador (2015–2023): A Population-Based Cross-Sectional Study

This population-based study of over 2.4 million births in Ecuador (2015–2023) reveals a significant increasing trend in preterm birth rates alongside persistent geographic, ethnic, and maternal age inequalities, with altitude identified as a critical determinant of territorial disparity.

Eudoxia Georgina Muñoz Ortiz, Tamara Francisca Otzen Hernández, Carlos Guillermo Manterola Delgado, Antonio Sanhueza, Ma (…)2026-07-16
📄 medicine

A Randomised Feasibility Study of a Transdiagnostic Intervention Targeting Alcohol Misuse and Psychological Distress Among Men Affected by War in Ukraine

This feasibility study demonstrates that the CHANGE transdiagnostic psychological intervention is acceptable and feasible for reducing alcohol misuse and psychological distress among war-affected men in Ukraine, particularly when delivered remotely, thereby supporting progression to a definitive randomised controlled trial.

Sergiy Bogdanov, Vita Kachai, Kateryna Harbar, Alona Pastukhova, Carine van der Boor, Melissa Neumann, Kostyantyn Dumche (…)2026-07-16
📄 medicine

Association of iron status with all-cause and cardiovascular mortality in individuals with Cardiovascular-Kidney-Metabolic syndrome stages 0-3

This study utilizing NHANES data reveals that in individuals with Cardiovascular-Kidney-Metabolic (CKM) syndrome stages 0-3, both excessively low and high ferritin levels, as well as low total iron-binding capacity (TIBC), are significantly associated with increased all-cause mortality, while low ferritin specifically predicts higher cardiovascular disease mortality.

yijing zhao, Qifeng Wang, Yingying Fu, Yu Yang, Wen Cao, Kun Wang, Chao Liu2026-07-16
📄 medicine

Development and Validation of the ALS Gastrointestinal Symptom Scale (ALS-GIS): A Brief Patient-Reported Outcome Measure for Amyotrophic Lateral Sclerosis

This study presents the development and validation of the ALS-GIS, a brief six-item patient-reported outcome measure that effectively assesses diarrhea and digestive discomfort in ALS patients and demonstrates meaningful correlations with respiratory function and serum albumin levels.

Claudia Emmanuela Sanchis-Sanchis, Jesús Privado, David Sancho-Cantus, Jose Enrique de la Rubia Ortí2026-07-16
📄 medicine

Association between underweight and teicoplanin trough concentrations in older patients: A single-center retrospective cohort study

This single-center retrospective cohort study reveals that older underweight patients exhibit lower teicoplanin trough concentrations and a blunted dose-response relationship compared to controls, suggesting that higher loading doses may be necessary to achieve optimal therapeutic levels and clinical efficacy in this vulnerable population.

Emi Nakatsugawa, Kohei Sazanami, Eiji Shiwaku, Masakatsu Hishizawa, Yuka Kobayashi2026-07-16
📄 medicine

Epidemiology and serotypic distribution of Group B Streptococcus Colonization in Shenyang: Associations with Adverse Pregnancy Outcomes and Risk Factors

This study of pregnant women in Shenyang identifies advanced maternal age, gestational diabetes mellitus (GDM), and vulvovaginal candidiasis (VVC) as independent risk factors for Group B Streptococcus (GBS) colonization, reveals serotypes Ib and V as predominant strains with serotype V specifically linked to GDM, and advocates for early screening, enhanced monitoring of high-risk groups, and strict intrapartum antibiotic prophylaxis to mitigate adverse pregnancy outcomes.

Xiaona Wang, Meiru Wang, Jialin Wang, Chenglong Tong, Shijiao Yuan, Xueyi Shang, Xin Huang, Yudong Wu, Kebin XU, Yanshuo (…)2026-07-16