📄 medicine

Safety Profile of Intrathecal Morphine in Obese Parturients Undergoing Caesarean Delivery: A Retrospective Study

This retrospective study of 400 obese parturients undergoing caesarean delivery demonstrates that a standard 0.1 mg dose of intrathecal morphine provides effective early postoperative analgesia with manageable side effects and no incidence of respiratory depression, supporting its safe use in this high-risk population.

Mohd Hamdi Che Yusoff, Azlina Masdar, Izzuddin Azaharuddin, Wan Rahiza Wan Mat, Nadia Md, Iskandar Khalid, Mohd Khazrul (…)2026-10-20
📄 medicine

Stable and Interpretable Cognitive Status Screening Using Longitudinal Wearable Data

This study presents an interpretable hierarchical framework that utilizes longitudinal wearable data to distinguish between cognitively normal, mild cognitive impairment, and dementia states with promising accuracy, while identifying specific physiological patterns associated with each condition to support risk screening and hypothesis generation.

Haeun Kim, Taewan Cho, Andrew Jaeyong Choi, Seon-Heui Lee2026-10-20
📄 medicine

Anatomical Constraints to Flexor Hallucis Longus Passage Through the Digital Flexor Sheath: A Cadaveric Study

This cadaveric study demonstrates that while an intact flexor hallucis longus tendon can generally pass through the A2 pulleys of the index, middle, and ring fingers, its passage is frequently restricted or impossible at the A4 pulley and in the little finger and thumb, highlighting significant anatomical constraints for its use as a graft.

Anaelle Le Ru, Ninon Caudmont, Pierre-Emmanuel Chammas, Marion Bodere, Gaelle Maroteau, Thomas Daoulas2026-10-20
📄 medicine

PTRH2 promotes the destruction of neurovascular units and glial scar hyperplasia after cerebral ischemia/reperfusion

This study demonstrates that Peptidyl-tRNA hydrolase 2 (PTRH2) is upregulated following cerebral ischemia/reperfusion, where its neuron-specific expression exacerbates early neurovascular unit damage and its astrocyte-specific expression promotes glial scar hyperplasia, likely through the regulation of the AKT signaling pathway.

Yingju Wang, Min Xu, Yifan Wang, Zhengqin Gao, Hongxue Sun, Chen Wang, Qiming Feng2026-10-20
📄 medicine

Protecting_the_protectors: _occupational_health_and_safety_of_h ealth_workers_in_Sierra_Leone_–_a_systems_analysis

This mixed-methods study of 54 healthcare facilities in Sierra Leone reveals critical systemic gaps in occupational health and safety, including inadequate protective equipment, low reporting of injuries, and workforce instability, thereby underscoring the urgent need for policy reform, sustained investment, and robust reporting systems to protect health workers.

Alhaji Brima Gogra, Bockarie Pompay Sesay, Samilia Edden Kamara2026-10-20
📄 medicine

Governing Digital Health for Noncommunicable Diseases Equity Gender and Sustainable Health Systems in Developing Economies

This qualitative analysis of 40 NCD documents from 2010–2026 reveals that while digital health is increasingly central to noncommunicable disease governance in developing economies, its potential to ensure equity, gender inclusion, and sustainability is often undermined by inadequate governance frameworks and a significant lack of gendered policy focus.

Neha Agarwal, Govind Kumar, Suryansh Saxena2026-10-20
📄 medicine

Chronic PICA Territory Infarction Presenting as Isolated Inferior Cerebellar Peduncle Atrophy: A Case Report and Quantitative Radiological Analysis

This case report describes a 55-year-old female with chronic vestibular symptoms caused by a PICA territory infarction, which resulted in rare, isolated inferior cerebellar peduncle atrophy that was confirmed through quantitative MRI analysis.

Isah Aminu, Nasir Abubakar Bakiyawa, Yahaya Mohammed, Abdullahi Y. Musa, Abdulmalik Saminu2026-10-20
📄 medicine

Two-Year Computed Tomography Evaluation of Non-Union in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis: Risk Zones and Clinical Outcomes

A two-year CT evaluation of 108 adolescent idiopathic scoliosis patients revealed a 13% non-union rate, predominantly occurring at the distal end of the fusion construct, which was significantly associated with pedicle screw loosening and reduced patient satisfaction.

Hiroki Oba, Tetsuhiko Mimura, Shota Ikegami, Masashi Uehara, Daisuke Kurogochi, Takuma Fukuzawa, Shinji Sasao, Yasuhiro (…)2026-10-20
📄 medicine

Prediction of growth and nutritional status using circumference measurements among preschool children in Jalpaiguri West Bengal India

This cross-sectional study of 1,240 preschool children in Jalpaiguri, India, demonstrates that head, chest, and mid-upper arm circumferences are effective screening tools for undernutrition, with chest circumference emerging as the strongest predictor for underweight and stunting while mid-upper arm circumference is superior for identifying wasting.

Arindam Biswas, Argina Khatun, Nitish Mondal, Kaushik Bose2026-10-20