📄 medicine

Evaluation of Attitudes and Related Factors Regarding Mammography Among Women Participating in Screenings at a University Hospital

This cross-sectional study of 300 women at a Turkish university hospital found that physician recommendation, family history of breast cancer, and perceived susceptibility are significant predictors of positive attitudes toward mammography, underscoring the need for targeted awareness campaigns and strengthened primary care roles to improve screening participation.

Aysun Aras, Fadime Güven, Metin Kuzulugil2026-07-02
📄 medicine

Unified tools for assessing the methodological quality of intervention effects in rapid reviews: a scoping review

This scoping review identified 29 unified tools designed to assess the methodological quality of both randomized and non-randomized studies for use in rapid reviews, but highlights significant limitations in their structural consistency, guidance availability, and psychometric validation that currently hinder their widespread adoption.

Deborah Edwards, Emily C Clark, Judit Csontos, Maureen Dobbins, Elizabeth Gillen, Juliet Hounsome, Sarah E. Neil-Sztramk (…)2026-07-02
📄 medicine

Standard-of-Care vs. Machine Learning–Recommended Discharge Destinations for Geriatric Surgical Inpatients: Algorithm Development and Internal Validation

This study demonstrates that an internally validated machine learning model significantly outperforms standard-of-care decisions in predicting individualized discharge destinations for geriatric surgical inpatients, achieving 82% accuracy and identifying key predictors such as the Barthel Index and Clinical Frailty Scale.

Thomas Derya Kocar, Utz Lovis Rieger, Filippo Maria Verri, Pauline Maier, Christoph Leinert, Simone Brefka, Christian Bo (…)2026-07-02
📄 medicine

Profile of Those with Recent Diagnosis of Psychiatric Illness: Participation, Cognition, and Sensory modulation

This study identifies that reduced participation in daily occupations, unemployment, and fluctuating enjoyment of activities, alongside specific cognitive and sensory differences, serve as sensitive early markers for distinguishing individuals with recent psychiatric diagnoses from healthy controls, offering a potential pathway for improved early detection and intervention.

Tami Bar-Shalita, Ayelet Hershkovitz, Mira Bukai, Lena Lipskaya-Velikovsky2026-07-02
📄 medicine

Trio-WES with CNV-seq for Genetic Diagnosis of DD/ID in Children: A Single-Center Study in China

This single-center study in China demonstrates that combining trio whole-exome sequencing with copy number variation sequencing significantly improves the diagnostic yield for developmental delay and intellectual disability in children, while also identifying novel genetic variants and suggesting potential roles for nitrogen and sulfur metabolism in the condition's pathogenesis.

Aojie Cai, Peina Jin, Yu Zhang, Yao Wang, Jiechao Niu, Jiandong Wang, Wei Wang, Zheng Chen, Wei Ma, Erhu Wei, Zhihong Zh (…)2026-07-02
📄 medicine

Therapeutic Effects of Phosphatidylserine on Functional Recovery After Spinal Cord Injury

This study demonstrates that phosphatidylserine (PS) treatment, particularly at a dose of 40 mg/kg, significantly promotes functional recovery and reduces neuropathic pain in a rat spinal cord injury model by suppressing inflammatory cytokines and inhibiting key signaling pathways (MAPK, ERK1/2, and NF-κB), thereby offering a promising therapeutic adjunct to current treatments.

Ali Darabniya, Reza Fazeli, Sara Shahriari, Seyed Mohammad Tavangar, Ramin Goudarzi, Alireza Partoazar, Ahmad Reza Dehpo (…)2026-07-02
📄 medicine

Endoluminal Complement Accessibility as a Spatial Determinant of Glomerular Injury: A Systematic Review with Integrated Narrative Analysis

This systematic review proposes that the architectural pattern of inflammatory glomerular injury is determined not merely by the presence of complement deposition, but specifically by its endothelial accessibility, which dictates whether neutrophil-mediated damage occurs within the glomerular capillary lumen or in extraglomerular compartments.

George N. Zsidisin, Sophia Talha2026-07-02