3171 papers
This study demonstrates that HyperSight cone-beam CT can achieve Level III external dosimetry audit compliance comparable to fan-beam CT for standard radiotherapy plans, though its use in stereotactic body radiotherapy (SBRT) requires extreme caution due to higher sensitivity to imaging uncertainties.
This prospective Phase II clinical trial demonstrates that MR-guided focused ultrasound-enhanced liquid biopsy (Sonobiopsy) safely and significantly improves the diagnostic accuracy of distinguishing true tumor progression from pseudoprogression in glioblastoma patients by transiently opening the blood-brain barrier to enrich plasma circulating tumor DNA.
This systematic review and network meta-analysis of 40 randomized trials involving over 26,000 children and adolescents concludes that professionally applied fluoride varnish is the most effective topical fluoride agent for preventing dental caries in permanent dentition compared to inactive controls, although the overall evidence is limited by high risk of bias and sparse data.
This meta-analysis of five studies indicates that while robot-assisted ACL reconstruction results in significantly longer operative times and more consistent, shorter tunnel lengths (particularly in the tibia) compared to conventional freehand techniques, the clinical significance of these findings remains uncertain due to the limited sample size, substantial heterogeneity, and dependence on individual studies.
This in vitro study demonstrates that using alumina-toughened zirconia drills for guided implant site preparation does not increase thermal exposure compared to conventional drilling, although external irrigation remains critical for minimizing temperature rises, particularly during pilot drilling and at greater depths.
This prospective cohort study of colorectal cancer survivors found that higher physical activity levels and lower sedentary time over 12 months post-treatment are longitudinally associated with more robust diurnal cortisol rhythms, suggesting these behaviors as potential targets for interventions to improve stress regulation after cancer.
This epidemiological study of MRI-confirmed plantar fibromas reveals significant demographic variations in tumor characteristics and treatment patterns, noting that female, Hispanic, and Black patients tend to exhibit distinct MRI features or receive more aggressive interventions compared to their counterparts.
This retrospective study of 802 pediatric upper GI endoscopies concludes that routine biopsies from macroscopically normal mucosa rarely alter clinical management, suggesting that a selective biopsy strategy guided by symptoms and guidelines is more effective.
This study challenges the conventional belief that improved water and sanitation infrastructure monotonically reduces dengue risk, revealing instead that the disease burden peaks during transitional phases of urban development—specifically when partial coverage of piped water and septic-connected flush toilets creates breeding grounds—before declining only after infrastructure systems are fully completed and consolidated.
This clinical feasibility study demonstrates that a Physics-Informed Neural Network framework, integrated with high-frame-rate ultrasound imaging, can successfully perform noninvasive, patient-specific mapping of localized arterial compliance and lumen pressure in both healthy and stenotic carotid arteries, supporting its potential for personalized cardiovascular risk assessment.