📄 Category

medicine

3171 papers

📄 medicine

Development of Inflammatory Models Using Differentiated Human Bronchial Epithelial (HBE) Cells from Cystic Fibrosis Patients for the Pre-Clinical Evaluation of Novel Therapeutic Compounds

This study establishes and validates a robust ex vivo model of cystic fibrosis airway inflammation using differentiated primary human bronchial epithelial cells from patients, demonstrating its efficacy in reproducing key inflammatory responses to various stimuli and highlighting its potential as a valuable tool for preclinical evaluation of novel anti-inflammatory therapies.

Chiara Tupini, Valeria Capurro, Nicoletta Pedemonte, Giulio Cabrini, Ilaria Lampronti2026-07-16
📄 medicine

Balanced Energy-Protein Supplementation Radically Modifies Multi-Matrix, Multi-Omics Profiles in Mother-Infant Dyads in Rural Burkina Faso: a Randomized Controlled Trial

This randomized controlled trial in rural Burkina Faso demonstrates that balanced energy-protein supplementation during pregnancy, rather than postnatally, drives sustained infant growth benefits through coordinated multi-omics changes across maternal, milk, and infant compartments, with milk IgA identified as a key molecular mediator.

Trenton Dailey-Chwalibóg, Lishi Deng, Laeticia Toe, Anderson Compaore, Andrew Mertens, Annie Moradian, Bruno De Meulenae (…)2026-07-16
📄 medicine

From Gestational Age–Specific Serum Creatinine Trajectories to an Interactive Clinical Interpretation Tool in Level IV NICU Infants

This study analyzed data from over 34,000 infants across ten Level IV NICUs to characterize gestational age-specific serum creatinine trajectories and develop an interactive clinical tool to aid in the interpretation of kidney function values in neonates.

Jennifer Rumpel, Sofia Perazzo, Andrew South, Elizabeth Bonachea, Mona Khattab, matthew Gillen, Joseph Asante, Semsa Gog (…)2026-07-16
📄 medicine

Does Generation Z cope with stress differently? Self-efficacy, coping strategies and implications for nursing workforce management: a cross-sectional survey study

This cross-sectional survey of 760 nurses in Poland reveals that while Generation Z nurses possess self-efficacy levels comparable to older generations, they employ more active and support-based coping strategies and fewer avoidant ones, suggesting that effective workforce management should combine self-efficacy building with targeted social support, mentoring, and work-life balance protections.

Małgorzata Paplaczyk-Serednicka, Magdalena Staszkiewicz, Patrycja Wierzbiak, Elżbieta Musz, Anita Orzeł-Nowak, Ilona Kuź (…)2026-07-16
📄 medicine

Cognitive Load Modulates Brain-Body Association in Hypertension During Dual-Task Standing: An fNIRS Study

This fNIRS study reveals that under high cognitive load, individuals with hypertension exhibit greater postural instability and rely on compensatory muscle recruitment driven by premotor cortical activation, whereas normotensive controls maintain efficient sensorimotor integration characterized by negative correlations between cortical activity and postural sway.

Qin Wang, Baizhi Qiu, Yingchao Liu, Huimin Qin, Qiuru Yao, Minghui Tang, YuYing Mo, Siyin Long, Xinran Shuai, Na Chen, L (…)2026-07-16
📄 medicine

The Relationship Between Selective Serotonin Reuptake Inhibitor Use and Delayed Bleeding After Colorectal Endoscopic Resection: A Nationwide Retrospective Cohort Study

This nationwide retrospective cohort study found that selective serotonin reuptake inhibitor (SSRI) use is not significantly associated with an increased risk of delayed bleeding after colorectal endoscopic resection, supporting the safety of continuing SSRIs perioperatively for standard procedures.

Hiroki Asano¹, Kazuhiko Ikeuchi², Takayuki Kishida², Hiroyuki Hisada¹, Yosuke Tsuji¹, Nobutake Yamamichi¹, Kazuya Okushi (…)2026-07-16
📄 medicine

Long-term health-related quality of life after proton therapy for benign brain tumors: a 5-year prospective follow-up Running title: Long-term HRQoL after proton therapy

This prospective 5-year follow-up study indicates that while health-related quality of life is largely preserved after proton therapy for benign brain tumors, patients experience specific persistent symptoms and modest functional declines that underscore the need for structured long-term survivorship care.

Per Fessé, Linda Åkeflo, Karin Ahlberg, Emelie Blomqvist, Per Fransson, Ingrid Kristensen, Kristin Kunni, Ulrica Langegå (…)2026-07-16
📄 medicine

Accuracy of the Garmin Venu for measuring heart rate, respiratory rate, and peripheral oxygen saturation in patients hospitalized in a respiratory ward: a validation study  

This validation study demonstrates that the Garmin Venu smartwatch provides clinically acceptable accuracy for measuring heart rate and peripheral oxygen saturation in hospitalized respiratory patients compared to hospital-grade monitors, though its respiratory rate measurements require caution, particularly at higher breathing rates.

Ruben Knevels, Elise Baert, Jelle Schils, Christophe Smeets, Zoë Pieters, Louis Van Slambrouck, Julie Vranken, Chris Bur (…)2026-07-16
📄 medicine

Prevalence and contributing factors of workflow interruptions among nurses in general hospitals in Kashan, Iran: a cross-sectional study

This 2024 cross-sectional study of 300 nurses in Kashan, Iran, reveals that workflow interruptions are highly prevalent, particularly in high-demand wards like the operating room and ICU, and are significantly influenced by factors such as ward type, overtime hours, and family income.

Seyyed Mohammad Abbaszadeh, Newsha Poursaadat, Niloofar Karimi, Reyhaneh Zarei, Nahid Dehghan Nayeri2026-07-16
📄 medicine

Burden, spectrum and predictors of neurological sequelae in children surviving acute bacterial meningitis in sub-Saharan Africa: a protocol for a systematic review and meta-analysis

This paper outlines a protocol for a systematic review and meta-analysis aimed at synthesizing the prevalence, clinical spectrum, and predictors of neurological sequelae in children surviving acute bacterial meningitis in sub-Saharan Africa to inform survivor care and public health strategies.

Kaweesi Calvin Nantalaga¹, Alice Nantege¹, Martha Nabirye¹2026-07-16