📄 medicine

Avoiding Data Leakage in Machine Learning Models for Diabetes and Hypertension Classification Using Routine Occupational Health Screening Data

This study demonstrates that including outcome-defining predictors like fasting blood glucose and blood pressure in machine learning models for diabetes and hypertension classification causes severe data leakage and artificially inflated performance, whereas models excluding these variables using routine occupational screening data achieve moderate but clinically realistic accuracy while highlighting the predictive value of factors such as age, BMI, and psychological distress.

Ghasem Alizadeh-dizaj, Mohammad Amiri-Ara, Ehsan Teymourzadeh, Parisa Mehdizadeh, Mehdi Mesri, Maryam Yaghoubi2026-10-20
📄 medicine

Who Uses Online Support Services? Mental Health, Help- Seeking and Reasons for Non-Use Among University Students

This study of university students in the enhance program found that while digital mental health services facilitated symptom reduction and further help-seeking, low engagement rates were primarily driven by barriers such as lack of time, motivation, and reluctance to discuss personal concerns with strangers.

Antonia Louise Schiel, Juliane Hug, Elisabeth Kohls, Aneliana da Silva Prado, Christine Rummel-Kluge2026-10-20
📄 medicine

"Would This Happen Again?" Addressing Recurrence Risks in Cyclopia: A Case Report

This case report highlights the devastating psychological impact on families when cyclopia is undiagnosed until delivery due to inadequate antenatal care and provider training, underscoring the urgent need for improved prenatal screening, specialized provider education, and compassionate support systems to address recurrence risks and facilitate emotional preparation.

GebreEgziabher Kassa Kebede, Solomon Teshome Mekonnen, Kidane Tsegaw Habtewold, Basazin Mulugeta Wodajjo, Ermias Fikru Y (…)2026-10-20
📄 medicine

Effect of Pre-labor Amniotomy Following Balloon Induction on Delivery Timing and Infectious Outcomes: A Propensity-Score-Matched Retrospective Cohort Study

This propensity-score-matched retrospective study suggests that performing pre-labor amniotomy after balloon induction accelerates delivery and increases the likelihood of vaginal birth within 24 hours without significantly increasing the risk of confirmed chorioamnionitis, although it is associated with a higher rate of intrapartum fever.

Ying Xu, Wenhui Li, Cuiping Feng, Yanting Chen, Zhenzhen Zhang, Xiaoyu Pan2026-10-20
📄 medicine

Ultrasound-Assisted Anatomy Teaching in Preclinical and Early Clinical Medical Education: A Scoping Review of Teaching Models, Outcomes, and Implementation Gaps

This scoping review of 11 studies published between 2015 and 2026 concludes that while ultrasound-assisted anatomy teaching in preclinical medical education effectively enhances student engagement, confidence, and short-term understanding through diverse models like hands-on and blended learning, current evidence regarding long-term retention and clinical transfer remains limited and inconsistent, highlighting a need for standardized, longitudinal, multi-institutional research.

Naaven Kumar Anantharao, Yasith Mathangasinghe, Vidya Kushare, Norfarahin Abdullah Sani, Amudha Kadirvelu, Thirupathirao (…)2026-10-20
📄 medicine

Development and validation of a three-marker urine DNA methylation assay complementary to mpMRI for pre-biopsy risk stratification of clinically significant prostate cancer

This study developed and validated a non-invasive three-marker urine DNA methylation assay that, when combined with multiparametric MRI, significantly improves the sensitivity for detecting clinically significant prostate cancer compared to MRI alone, offering a promising tool for refining pre-biopsy risk stratification.

Tae Jeong Oh, Chung Lyul Lee, JaeJin Lee, Min A Woo, Su Ji Kim, Yangyei Seo, Changshik Yoon, Ju Hyun Shin, Sungwhan An2026-10-20
📄 medicine

Surgical difficulty and factors associated with conversion to thoracotomy after neoadjuvant chemoimmunotherapy for non-small cell lung cancer: a single- center retrospective study

This single-center retrospective study of 101 NSCLC patients found that higher clinical T stage and complex hilar anatomy (specifically pulmonary artery and bronchial relationships) on preoperative CT are key predictors of conversion from VATS to thoracotomy following neoadjuvant chemoimmunotherapy, a conversion that increases operative time and blood loss but should be viewed as a safety strategy rather than surgical failure.

Guicheng Pan, Lingling Geng, Qian Luo, Pan Chen, Jiajie Zhou, Lv Sun, Xianli Luo, Junliang Ma, Wendong Qu, Yongxiang Son (…)2026-10-20
📄 medicine

Demographic and Behavioral Analysis of Patients’ Management of Dental Abscesses and Assessment of Their Awareness: An Analytical Cross-Sectional Study in Damascus, Syria Running Title: Dental Abscesses Care-Seeking in Syria

This analytical cross-sectional study conducted in Damascus, Syria, reveals that despite a strong preference for medical treatment, nearly 60% of dental abscess patients delay seeking professional care due to misconceptions, fear, and financial constraints, with higher educational levels identified as the sole independent predictor of appropriate health-seeking behavior.

Mohamad Sif Eddin, Kamar Al-Hayek, Ali Hatem Ali, Fadi Al-Hussain2026-10-20
📄 medicine

Longitudinal intratumoral and peritumoral MRI radiomics for predicting pathologic complete response to neoadjuvant chemoimmunotherapy in locally advanced head and neck squamous cell carcinoma: a retrospective two-center study

This retrospective two-center study demonstrates that a clinical-spatiotemporal radiomics model integrating longitudinal intratumoral and peritumoral MRI features with clinicopathologic factors significantly improves the preoperative prediction of pathologic complete response to neoadjuvant chemoimmunotherapy in locally advanced head and neck squamous cell carcinoma.

Shitong Lou, Ling Duan, Xinyu Li, Changyu Zhu, Yijun Shi, Weitao Zhang, Shuyang Zhang, Heshu Liu, Wei Li2026-10-20