📄 medicine

The Right Posterior Carotid Sheath Channel: A Potential Anatomical Structure Associated With Lymph Node Metastasis in Papillary Thyroid Carcinoma

This prospective case series identifies a previously overlooked anatomical region, the right posterior carotid sheath channel, as a site of lymph node metastasis in 12.1% of papillary thyroid carcinoma patients, suggesting it may represent a distinct lymphatic pathway that warrants further investigation before routine surgical dissection is recommended.

Jia zhi Wang, Jiayu Huang, Jingran Wang, Jingchao Xu, Yongfu Zhao2026-10-20
📄 medicine

​​Shallow Medial Tibial Plateau Depth is Independently Associated with Medial Meniscus Posterior Root Tear after Adjustment for Alignment and Morphological Parameters: A Multivariate Analysis

This retrospective study of 164 knees with early-stage osteoarthritis identifies shallow medial tibial plateau depth as an independent predictor of medial meniscus posterior root tears, alongside increasing age and higher BMI, even after adjusting for coronal alignment and medial posterior tibial slope.

Toshiki Kohara, Yuki Okazaki, Takayuki Furumatsu, Yusuke Yokoyama, Takaaki Hiranaka, Koki Kawada, Daiichiro Yokomizo, To (…)2026-10-20
📄 medicine

Co-designing a nutritional prehabilitation solution for head and neck cancer patients receiving radiotherapy: A novel participatory approach

This study employed a novel Living Labs participatory approach to co-design a nutritional prehabilitation intervention for head and neck cancer patients undergoing radiotherapy, resulting in three user-centered solutions aimed at overcoming barriers to treatment readiness and improving wellbeing.

Linda A Cantwell, Joanne M. Patterson, Grahame Smith, Mary Gemma Cherry, Nefyn Williams, Alison Bryant, Greg Hunt, Carol (…)2026-10-20
📄 medicine

First ICU-day red blood cell transfusion burden and subsequent ICU delirium after cardiac surgery: a 24-h landmark study using MIMIC-IV

This retrospective cohort study using MIMIC-IV data reveals that red blood cell transfusions administered within the first 24 hours after cardiac surgery are significantly associated with an increased risk of subsequent ICU delirium, with the risk rising in a dose-dependent manner.

Lezhen Wang, Ying Han, Xiaotian Ma, Xuanlong Wang, Penghui Wei, Jie Guo, Guang-fen Zhang, Jianjun Li2026-10-20
📄 medicine

Evaluation of the cervical cancer surveillance system in Kigali City, Rwanda: a descriptive cross-sectional study, January 2023–June 2025

This descriptive cross-sectional study evaluating Rwanda's cervical cancer surveillance system in Kigali City from January 2023 to June 2025 found that the system performs well to very well across key attributes like data quality and timeliness, though its overall effectiveness is currently limited by high loss to follow-up among HPV-positive women and moderate system flexibility.

Alice UWIMANA, Bibiane UWAMAHORO, Jean Claude NIYOYITA, Emmerance IGIHOZO HIRWA, Irene BUGINGO, Solange NYINAWABEZA, Jer (…)2026-10-20
📄 medicine

Cancer Patient Perspectives on the Opioid Treatment Agreement: Tool for Safety or Symbol of Distrust?

A survey of 89 adult cancer patients at a tertiary center reveals that while the vast majority find opioid treatment agreements clear, relevant, and protective of their safety, a significant minority (28%) still harbor concerns or questions, highlighting the need for improved communication and education regarding these tools.

Sriram Yennu, Serena Jiyeon Kim, Eduardo Bruera, Loretta A. Williams, Saba Javed, Alice Ye, Lei Feng, Dhanalakshmi Koyya (…)2026-10-20
📄 medicine

Predictors of Maternal Sensitive Engagement in a peri-urban LMIC context – The Drakenstein Child Health Study

In a peri-urban LMIC context, this Drakenstein Child Health Study sub-study found that higher maternal depression significantly predicts lower sensitive engagement, while some factors typically associated with sensitivity in high-income countries did not show similar effects in this high-risk setting.

Anita Prag, Marilyn Lake, Nadia Hoffman, Heather Zar, Dan J. Stein, Susan Malcolm-Smith2026-10-20
📄 medicine

Immediate curettage versus conservative management following medically induced second-trimester abortion: a retrospective cohort study comparing maternal outcomes

This retrospective cohort study of 240 patients suggests that immediate curettage following medically induced second-trimester abortion does not significantly reduce the risk of pathologically confirmed retained products of conception or improve short- and long-term maternal outcomes compared to conservative management, although the findings are limited by the study's non-randomized design.

Ishai Heusler, Adi Anis Heusler, Noee Naim, Shaked Yarza, Yair Daykan, Zvi Klein, Ron Schonmam, Yael Yagur2026-10-20
📄 medicine

Exploratory Associations of Systemic Inflammatory Markers and Prostate Volume with Predominant Gleason Pattern in Gleason Score 7 Prostate Cancer

This exploratory study of 26 patients suggests that combining the neutrophil-to-lymphocyte-to-platelet ratio (NLPR) with prostate volume may offer preliminary, though unvalidated, utility in distinguishing between Gleason 3+4 and 4+3 prostate cancers, warranting further investigation in larger cohorts.

Feng Guo, Aerken Maolake, Jianhua Zhao, Bide Liu, Wenlong Fan, Zecheng Ni, Jiuzhi Li2026-10-20