13396 papers
This single-center retrospective study characterizes a growing, geographically diverse population of surgical candidates who decline cholecystectomy in favor of organ preservation, demonstrating that the GO-SCOPE procedure provides durable 12-month symptom relief with a favorable safety profile for patients with symptomatic cholelithiasis.
This mixed-methods study in Homa Bay County reveals that Kenya's 2024 transition from free maternity care to Social Health Insurance (SHIF) has reproduced and amplified existing inequities in maternal healthcare access, particularly for adolescents, unemployed women, and users of lower-level facilities, due to barriers in timely enrolment, persistent out-of-pocket costs, and limited facility reimbursement.
This systematic review and meta-analysis of 11 studies involving 296 patients with AR-positive triple-negative breast cancer indicates that while AR pathway-targeted therapies yield limited tumor shrinkage (5.4% ORR), they provide durable disease control in approximately one-third of patients, though these findings are tempered by the reliance on small, single-arm trials with inconsistent definitions.
This study on amateur runners in Natitingou, Benin, demonstrates that running during severe heat stress significantly elevates physiological strain, with recovery time to safe levels being substantially prolonged by high wet-bulb globe temperatures and insufficient fluid intake, thereby supporting the need to avoid midday training and prioritize shaded, hydrated recovery.
This retrospective population-based study of 101 cases in Croatia (2010–2020) reveals a stable esophageal atresia birth prevalence of 2.64 per 10,000 live births with a 11.9% 30-day mortality rate, noting that while outcomes align with European data, prenatal diagnosis remains critically low at 3%.
This study utilizes quantitative susceptibility mapping to reveal that whole-brain magnetic susceptibility abnormalities are distributed across multiple cortical regions in patients with hepatitis B virus-related decompensated cirrhosis, with shared alterations in inferior frontal and superior temporal areas potentially serving as candidate markers for minimal hepatic encephalopathy.
A 2024 national survey of U.S. dermatology educators identified that the most frequently used and effective strategies for teaching store-and-forward teledermatology to residents are soliciting differential diagnoses, reviewing relevant morphology, and describing systematic approaches to diagnosis and management.
This cross-sectional study of 466 Indian medical students reveals that educational stress is significantly associated with depressive symptoms, with the strength of this relationship varying across professional years and being most strongly driven by specific dimensions such as poor educational support and future-oriented concerns rather than a single total stress score.
This study utilized a modified Delphi method to develop and validate a reliable framework of twenty Entrustable Professional Activities (EPAs) specifically designed to assess and guide the clinical training of novice nurses in Chinese Intensive Care Units.
In a cohort of Chinese adults with cardiovascular-kidney-metabolic syndrome stages 0–3, composite insulin resistance indices incorporating anthropometric measures (such as TyG-BMI and TyG-WHtR) demonstrated a more robust and independent association with incident chronic kidney disease than the triglyceride-glucose index alone, despite all indices showing limited predictive discrimination.