📄 medicine

Outcomes of Laparoscopic Versus Open Excision of Choledochal Cyst in Preschool-Aged Children: Analysis From a Nationally Representative Database

This study utilizing a nationally representative database found that while laparoscopic and open excision of choledochal cysts in preschool-aged children yield similar short-term complication rates, the laparoscopic approach offers superior perioperative recovery, reduced resource utilization, and shorter hospital stays.

Maria Grazia Sacco Casamassima, Nadeen Alturki, Janelle R. Noel-MacDonnell, Tolulope A Oyetunji, Shawn D. St. Peter2026-07-02
📄 medicine

Clinicopathological factors associated with brain metastases development among breast cancer patients receiving neoadjuvant chemotherapy

This retrospective study of 586 breast cancer patients receiving neoadjuvant chemotherapy identifies residual nodal involvement, inflammatory breast cancer, and HER2-positive or triple-negative subtypes as independent predictors of earlier brain metastasis development, suggesting a need for further investigation into targeted screening for these high-risk groups.

Jie Wei Zhu, Italo Fernandes, Julia Lopes, Veronika Moravan, William Tran, Katarzyna Jerzak2026-07-02
📄 medicine

Molar Incisor Hypomineralization and Self-perception of Mother's Positive Oral Health - a Comparative Cross-sectional Study

This comparative cross-sectional study found that mothers of children with Molar Incisor Hypomineralization (MIH), particularly severe cases, reported a lower self-perception of positive oral health compared to mothers of children without MIH, while higher maternal education levels were associated with a more positive oral health self-perception.

Letícia Cristine-Silva, Saul Martins Paiva, Jéssica Madeira Bittencourt, Raquel Vieira Vieira-Andrade, Marco Aurelio Ben (…)2026-07-02
📄 medicine

Tetrastigma hemsleyanum protects against sepsis-induced intestinal injury by suppressing TLR4/NF-κB signaling and macrophage polarization

Tetrastigma hemsleyanum protects against sepsis-induced intestinal injury in rats by modulating the gut microbiota–macrophage–TLR4/NF-κB axis, which suppresses inflammation, promotes M2 macrophage polarization, and restores intestinal barrier integrity.

Lisha Pang, Muhua Dai, Wei Zhang, Jianbiao Meng, Chunlian Ji, Jiayan Li, Jiahua Chi, Mahong Hu, Zhipeng Xu2026-07-02
📄 medicine

Fluctuating Arousal Failure with Repeatedly Negative DWI Preceding Artery of Percheron Infarction: A Case Report and Focused Literature Review

This case report describes a 65-year-old man who experienced recurrent transient arousal failure and ocular motor signs with initially negative DWI scans, ultimately diagnosed as an Artery of Percheron infarction, highlighting the critical need to prioritize clinical localization and serial imaging over normal early MRI findings when suspecting posterior-circulation stroke.

Yuke Ma, Hao Li, Jia Fan2026-07-02
📄 medicine

A Bibliometric Analysis of Artificial Intelligence Applications in Infectious Diseases: A Decade of Research (2016–2025)

This bibliometric analysis of 1,252 articles from 2016 to 2025 reveals an exponential growth in research on artificial intelligence applications for infectious diseases, driven largely by the COVID-19 pandemic and increasingly focused on clinical hotspots such as antimicrobial resistance surveillance and sepsis prediction.

Çağlar Irmak, Ahmet Furkan Süner, İlkay Akbulut, Sabri Atalay2026-07-02
📄 medicine

Honest Denominators: Post-ICSI Oocyte Degeneration Masks Conventional Laboratory KPIs, and Degeneration-Penalized and MII-Anchored Indices Reveal the True Outcome

This study demonstrates that conventional IVF success metrics overstate laboratory performance by excluding post-ICSI oocyte degeneration, and proposes two corrected indices (Degeneration-Penalized and True Blastocyst Utilization Rates) that reveal hidden attrition and more accurately identify underperforming operators.

Emrah Onder, Ibrahim Orcun Olcay, Tuba Duzcu, Mustafa Bahceci, Aydin Arici, Ozcan Duzcu, Murat Basar2026-07-02
📄 medicine

Clinicopathological Characteristics and Prognosis of Pediatric Immunoglobulin A Nephropathy: A Follow-up Exceeding 10 Years

This study demonstrates that pediatric IgA nephropathy generally has a favorable long-term prognosis exceeding 10 years, with failure to achieve proteinuria remission within six months and the presence of T1 tubular lesions identified as key predictors of poor outcomes, while high-dose methylprednisolone pulse therapy showed benefit for children with nephrotic-range proteinuria.

hua xia, ChaoYing Chen, Juan Tu, Hua Rong Li, Hai Yun Geng2026-07-02