6270 papers
A pre-conference workshop in Pakistan demonstrated that a brief, structured intervention can significantly improve knowledge and generate actionable strategies for overcoming the critical barriers of infrastructure, policy, and workforce limitations in implementing genomics services for recessive genetic disorders in low- and middle-income countries.
This cross-sectional study of 500 adults in Khyber Pakhtunkhwa, Pakistan, reveals that despite moderate support for subsidized services, the population suffers from severe knowledge gaps regarding genetic disorders, low utilization of existing genetic services, and significant barriers including cost, lack of specialists, and cultural concerns, highlighting an urgent need for culturally tailored, Pashto-language education and accessible district-level counseling.
This systematic review demonstrates that direct surgical access to a non-dilated, thrombosed, or angiographically occult superior ophthalmic vein is a viable and effective salvage strategy for embolizing carotid-cavernous fistulas when conventional transvenous routes fail, achieving high technical success and favorable clinical outcomes without access-related complications.
This retrospective study of 60 patients undergoing Lu-177 DOTATATE therapy identifies pre-treatment renal function as a key predictor for early radiation safety discharge, while suggesting that adequate oral hydration may help mitigate discharge delays in patients with impaired kidney function.
This systematic review and meta-analysis of 226 recipients found that kidney allografts with duplicated or multiple ureters have low urological complication rates comparable to standard single-ureter grafts, suggesting that routine discard of these anatomically variant kidneys is not supported by current evidence.
This study quantifies the severe public health and environmental hazards of informal street grilling in Latin America, revealing that the practice of igniting black charcoal with plastic bags and cooking high-fat meats generates toxic smoke and carcinogenic contaminants at levels drastically exceeding global safety standards compared to regulated regions.
This study elucidates the therapeutic mechanism of Panax Notoginseng Saponins (PNS) against alcohol-induced osteonecrosis of the femoral head by integrating network pharmacology, molecular dynamics simulations, and in vivo validation to demonstrate that PNS ameliorates the condition through a multi-component, multi-target approach primarily involving the inhibition of osteocyte apoptosis and modulation of the VEGF signaling pathway.
This study presents and validates a digital visual scale for assessing mucosal healing after third molar extraction, demonstrating that while the tool achieves high consensus for advanced healing stages and is widely accepted by dental professionals for standardizing postoperative evaluation, its inter-rater reliability remains fair and requires further refinement for intermediate healing stages.
This cross-sectional study of 360 Turkish women found that while posttraumatic stress symptoms, particularly hyperarousal and numbing, negatively predict quality of life during the puerperium, planned pregnancy and immediate skin-to-skin contact serve as significant protective factors.
This ecological study analyzes U.S. county-level data from 2018 to 2024 to reveal significant geographic clustering of Parkinson's disease mortality, identifying elevated hotspots primarily in the Midwest and South regions.