📄 medicine

Maternal Secondhand Smoke Exposure and Risk of Preterm Birth: A Systematic Review and Meta-Analysis With National Epidemiological Context From Indonesia

This systematic review and meta-analysis demonstrates that maternal secondhand smoke exposure significantly increases the risk of preterm birth (pooled OR = 1.63), a finding contextualized by high indoor smoking rates in Indonesia that underscores the urgent need for comprehensive tobacco control measures to protect maternal and neonatal health.

Belva Bhadranitya Buana, Ario Danianto, Roro Cahyowati, Gatot Dwi, Dayinta Liris Kawuryan2026-07-02
📄 medicine

MicroRNAs detect breast cancer in nipple aspirate fluid: results from a Dutch multicenter cross-sectional study

This Dutch multicenter study demonstrates that a 20-miRNA panel analyzed in nipple aspirate fluid can effectively discriminate between breast cancer patients and healthy controls with an AUC of 0.70, suggesting its potential as a non-invasive tool for personalized screening, particularly for women with dense breasts.

Laura A. de Rooij, Susana I.S. Patuleia, Bas B.L. Penning de Vries, Sjoerd G. Elias, Joost M. H. H. van Gorp, Julia E.C. (…)2026-07-02
📄 medicine

Factors Associated with the Cholera Epidemic in the Rural Health Zone of Shabunda, South Kivu, Democratic Republic of the Congo: A Matched Case-control Study

This matched case-control study in Shabunda, DRC, identifies that the severe cholera epidemic is driven by a convergence of environmental, socio-economic, and behavioral factors—specifically lack of water treatment, absence of handwashing kits, mining-related visitor exposure, and riverine proximity—which create a dose-response risk relationship necessitating urgent multi-sectoral WASH interventions.

KISULU KINYEMA Gaston, RIZIKI IDANGI Monique2026-07-02✓ Author reviewed
📄 medicine

Risk factors and nomogram prediction model for recurrence after CO2 laser treatment in women with condyloma acuminatum

This study identified independent risk factors for condyloma acuminatum recurrence in women following CO2 laser treatment—including sexually transmitted infections, immunosuppressant use, diabetes, hybrid HPV infection, multifocal lesions, and anxiety levels—and developed a validated nomogram model with high predictive accuracy to estimate relapse risk.

Chunchun Zou, Jingmin Yu, Yan Chen2026-07-02
📄 medicine

Associations between substance use and oppositional defiant disorder among U.S. adolescents: A national study of high-prevalence subgroups

This national study of over 226,000 U.S. adolescents found that cannabis use has the strongest association with oppositional defiant disorder (ODD), while machine learning analysis identified male adolescents aged 12–17 who use alcohol but not cannabis as the subgroup with the highest predicted probability of ODD, supporting the need for targeted screening in school settings.

Md Roungu Ahmmad, Xiaoli Zhang, Ukamaka Oruche2026-07-02
📄 medicine

Risk Factors for Pharyngocutaneous Fistula After Total Laryngectomy: An 11-year Retropective Cohort Study in Burkina Faso

This 11-year retrospective cohort study conducted in Burkina Faso identifies surgical site infection, advanced age, postoperative anemia, malnutrition, and prolonged operative time as significant risk factors for pharyngocutaneous fistula following total laryngectomy, highlighting the need for targeted preventive measures in sub-Saharan settings.

Adama YAMEOGO, Aboubacar Goueta, Yvette Gyebre2026-07-02
📄 medicine

Sexual identity as a moderator of associations between lifetime MDMA/ecstasy or psilocybin use and mental health outcomes: An exploratory analysis of a nationally representative sample using NSDUH 2015–2019

This exploratory analysis of nationally representative data found little evidence that sexual identity moderates the associations between lifetime MDMA or psilocybin use and mental health outcomes, with only non-significant-after-correction signals suggesting potential differences in how psilocybin relates to depression for heterosexual versus bisexual individuals.

Maya Seale2026-07-02
📄 medicine

Exposome-wide Association Patterns across Cardiovascular Disease Outcomes: Findings from the NHANES

This cross-sectional exposome-wide association study of 56,253 NHANES participants reveals that cardiovascular outcomes, particularly composite CVD and heart failure, exhibit distinct yet reproducible environmental exposure signatures, with blood cadmium and serum cotinine emerging as key risk factors across multiple disease endpoints.

Hao Wang, Yulu Zheng, Jian Geng, Zhiyuan Wu, Yahong Zhu, Ziqi Zhou, Hang Qu, Lois Balmer, Aimin Yang, Xingang Li, Zheng (…)2026-07-02