📄 Category

medicine

6270 papers

📄 medicine

Associations of cumulative exposure and dynamic trajectories of the Modified Life’s Essential 8 with incident cardiometabolic multimorbidity: a longitudinal analysis based on the China Health and Retirement Longitudinal Study (CHARLS)

This longitudinal study of Chinese adults demonstrates that higher baseline and cumulative Modified Life's Essential 8 (mLE8) scores, as well as sustained high mLE8 trajectories over time, are significantly associated with a reduced risk of developing incident cardiometabolic multimorbidity.

Wuhao Li, Zhengwen Xu, Zhehui Yin, Xiaojie Xie2026-07-02
📄 medicine

Health-related quality of life and its clinical and psychosocial correlates among men entering an in-prison substance-use rehabilitation programme in Indonesia: a cross-sectional study

This cross-sectional study of men entering an Indonesian in-prison substance-use rehabilitation program reveals that their health-related quality of life is substantially impaired and primarily associated with anxiety and marital status rather than the type of substance used, highlighting the need for integrated mental health screening in correctional settings.

Zikri Aulio Septiawan, Berlian Isnia Fitrasanti, Shelly Iskandar2026-07-02
📄 medicine

An Intervention Study Protocol on Reducing Polycyclic Aromatic Hydrocarbons (PAHs) via Nutritional Supplementation in Women of Reproductive Age

This study protocol outlines an 18-month randomized controlled trial in the Niger Delta to evaluate whether a targeted antioxidant micronutrient regimen can reduce polycyclic aromatic hydrocarbon (PAH) biomarkers and improve neonatal outcomes among women of reproductive age exposed to oil-related environmental toxins.

Kellybest Davids2026-07-02
📄 medicine

Beyond the Tap and the Latrine: Sanitation, Clean Drinking Water, and the Fight Against Child Stunting a Systematic Mapping Review of Evidence, Mechanisms, and Interventions

This systematic mapping review synthesizes evidence from 2010 to 2023 to demonstrate that inadequate sanitation and unsafe drinking water drive child stunting primarily through environmental enteric dysfunction, highlighting the need for context-specific, multi-sectoral WASH and nutrition interventions to achieve significant reductions in growth failure.

cahyani wulandari, Moses Glorino Rumambo Pandin2026-07-02
📄 medicine

Turnover intention and associated factors among employees of regional and city health regulatory bodies in Ethiopia. A cross-sectional study

This cross-sectional study conducted in Ethiopia reveals that 55.5% of employees in regional and city health regulatory bodies intend to leave their jobs, a trend significantly driven by dissatisfaction with salaries and organizational environments, as well as family separation, while adequate educational infrastructure for children serves as a protective factor.

Fitsum Zekarias, Sirak Damtew, Getahun Gebre, Tadesse Mamo, Esubalew Tesfahun, Mekasha Getnet2026-07-02
📄 medicine

Multilayered validation of graph attention autoencoder–derived drug repurposing candidates for COVID-19

This study presents a multilayered validation framework combining a Graph Attention Autoencoder (GATE) with real-world data and phenome analyses to identify and prioritize novel COVID-19 drug repurposing candidates, specifically highlighting cilastatin and megestrol as promising therapeutics supported by statistical and mechanistic evidence.

Yusuke Nakayama, Shingo Tsuji, Koji Yamamoto, Juran Kato-Suzuki, Kouichi Hosomi2026-07-02
📄 medicine

Evaluation of Attitudes and Related Factors Regarding Mammography Among Women Participating in Screenings at a University Hospital

This cross-sectional study of 300 women at a Turkish university hospital found that physician recommendation, family history of breast cancer, and perceived susceptibility are significant predictors of positive attitudes toward mammography, underscoring the need for targeted awareness campaigns and strengthened primary care roles to improve screening participation.

Aysun Aras, Fadime Güven, Metin Kuzulugil2026-07-02
📄 medicine

Unified tools for assessing the methodological quality of intervention effects in rapid reviews: a scoping review

This scoping review identified 29 unified tools designed to assess the methodological quality of both randomized and non-randomized studies for use in rapid reviews, but highlights significant limitations in their structural consistency, guidance availability, and psychometric validation that currently hinder their widespread adoption.

Deborah Edwards, Emily C Clark, Judit Csontos, Maureen Dobbins, Elizabeth Gillen, Juliet Hounsome, Sarah E. Neil-Sztramk (…)2026-07-02
📄 medicine

Standard-of-Care vs. Machine Learning–Recommended Discharge Destinations for Geriatric Surgical Inpatients: Algorithm Development and Internal Validation

This study demonstrates that an internally validated machine learning model significantly outperforms standard-of-care decisions in predicting individualized discharge destinations for geriatric surgical inpatients, achieving 82% accuracy and identifying key predictors such as the Barthel Index and Clinical Frailty Scale.

Thomas Derya Kocar, Utz Lovis Rieger, Filippo Maria Verri, Pauline Maier, Christoph Leinert, Simone Brefka, Christian Bo (…)2026-07-02
📄 medicine

Profile of Those with Recent Diagnosis of Psychiatric Illness: Participation, Cognition, and Sensory modulation

This study identifies that reduced participation in daily occupations, unemployment, and fluctuating enjoyment of activities, alongside specific cognitive and sensory differences, serve as sensitive early markers for distinguishing individuals with recent psychiatric diagnoses from healthy controls, offering a potential pathway for improved early detection and intervention.

Tami Bar-Shalita, Ayelet Hershkovitz, Mira Bukai, Lena Lipskaya-Velikovsky2026-07-02