📄 medicine

Access to and Utilisation of Primary Healthcare Services among North-South Migrants in Kumasi, Ghana: A Cross-Sectional Mixed-Methods Study

This mixed-methods study of north-south migrants in Kumasi, Ghana, reveals that while physical access to healthcare facilities is high, utilization remains low due to financial constraints, inadequate National Health Insurance Scheme coverage, long waiting times, and cultural barriers, with usage patterns significantly influenced by gender, marital status, employment stability, and duration of stay.

Seth Oppong-Mensah, Daniel Buor, Prince Osei Wusu Adjei, David Forkuor2026-10-20
📄 medicine

Preparation and in‑vitro screening of yak‑skin collagen/PMVE‑MA composite biomaterials toward biodegradable vascular stents

This study develops a biodegradable yak-skin collagen/PMVE-MA composite for vascular stents that offers improved thermal stability and hemocompatibility but requires surface modification to overcome its inherent hydrophobicity, which currently hinders essential cellular adhesion and infiltration.

Songhao Liu, Juan Yan, Yuxia Zhang, Lin Rong, Liang Gao, Lixin Wei, Hongxia Yang, Mengyu Gao2026-10-20
📄 medicine

Hearing age gap as a marker of auditory ageing and its association with mortality: a nationally representative cohort study

This nationally representative cohort study demonstrates that a machine learning-derived "hearing age gap," which captures the frequency-specific configuration of hearing loss rather than its overall severity, serves as an independent predictor of mortality risk beyond conventional audiometric measures.

Xin Qi, Shuo Liu, Qiuchen Zheng, Beicheng Li, Pu Dai, Yu Su2026-10-20
📄 medicine

Accounting for Spatial Dependence in Neighborhood Perceived Social Isolation: An Analysis of Florida Census Tracts

This study of Florida census tracts reveals that while perceived social isolation exhibits significant spatial clustering, accounting for this spatial dependence renders differences between urban, suburban, and rural areas statistically nonsignificant, suggesting that public health strategies should prioritize localized hotspots over broad administrative classifications.

Andre Antonio Alexander Williams2026-10-20
📄 medicine

Phage display-derived TCR-T cells targeting KRASG12V and CTAG1B suppress colorectal and esophageal tumors

This study demonstrates that a phage display-based workflow successfully identified and validated highly specific TCRs targeting the KRASG12V neoantigen and CTAG1B cancer-testis antigen, which, when engineered into T cells, effectively suppressed colorectal and esophageal tumors in xenograft models with minimal off-target toxicity.

Obed Amissah, Wenfang Chen, Belinda Baiden, Rajesh Basnet, Zhiyuan Li, Gloria Kim2026-10-20
📄 medicine

What counts as training capacity? Professional identity and educational readiness for postgraduate medical training expansion in Ireland: a qualitative multistakeholder case study

This qualitative multistakeholder case study reveals that professional identity significantly shapes how Irish stakeholders define and prioritize training capacity for postgraduate medical expansion, leading to the development of an Educational Readiness Framework that reconciles conflicting service, educational, and regulatory demands to ensure sustainable growth.

Martin McCormack¹2026-10-20
📄 medicine

Gender roles and women’s pain experience: a systematic review

This systematic review of 19 studies published between 2015 and 2025 reveals that women's chronic pain is shaped by a complex interplay of biological, psychosocial, and sociocultural factors—including gender roles and structural inequalities—necessitating a shift from purely biomedical models to integrative, gender-sensitive approaches in research and clinical practice.

Thaís Brito Vilela, Paulo Eduardo Evangelista, Daniele Cunha van Eijk, Izabella Brito França, Sofia Guimarães Mazzo2026-10-20
📄 medicine

From Cue Exposure to Situated Action: Immersive, Embodied, and Socially-Oriented Technologies for Alcohol Use Disorder.

This narrative review synthesizes research on immersive, embodied, and socially-oriented technologies for Alcohol Use Disorder, arguing for a conceptual shift from passive cue exposure to situated action where users actively rehearse coping strategies in ecologically valid environments, while positioning these tools as promising adjuncts to established treatments rather than standalone interventions.

Flavien Ehret, Yannick Francillette, Bob-Antoine J. Menelas2026-10-20
📄 medicine

Association Between Self-Efficacy and Knowledge, Attitudes, and Practices Regarding pulmonary rehabilitation Among Clinical Nurses: A Cross-Sectional Study

This cross-sectional study of 679 clinical nurses reveals that higher self-efficacy and prior pulmonary rehabilitation training are significantly associated with improved knowledge, attitudes, and practices regarding pulmonary rehabilitation, suggesting that targeted interventions to boost self-efficacy could enhance care for COPD patients.

HuiMin Zhou, LiFang Qiu, BiLan Yi, XiuYan Lan2026-10-20