📄 medicine

Multidrug-resistant Serratia liquefaciens urinary tract infection in chronic kidney disease: a case report

This case report describes a multidrug-resistant *Serratia liquefaciens* urinary tract infection in a 66-year-old woman with chronic kidney disease, emphasizing the critical need for accurate species identification and tailored antimicrobial therapy based on susceptibility testing in high-risk patients with complicated urinary tract conditions.

Kaushik Sahoo, Shital Mahajan, Gargi Mudey, Radha Kunjalwar, Tokeshwar Kumar Sahu2026-07-16
📄 medicine

The different positivity rates of PLA2R immunohistochemical staining in paraffin embedded kidney tissue among various preservation conditions

This study demonstrates that the positivity rate of PLA2R immunohistochemical staining in paraffin-embedded kidney tissue significantly declines with prolonged room temperature storage but remains stable when slides are stored at -20°C, highlighting the critical need for optimized preservation protocols to ensure diagnostic reliability in idiopathic membranous nephropathy.

Shuang Sui, Xiaojuan Yu, Suxia Wang, Li Yang, Yiyi Ma2026-07-16
📄 medicine

A Mixed Methods Analysis of Behavioural and Structural Drivers of Matenal, Sexual and Reproductive Health Services Disruption During and Post Covid-19 in Zimbabwe

This mixed-methods study across Zimbabwe reveals that the COVID-19 pandemic exacerbated maternal, sexual, and reproductive health service disruptions through a convergence of "dual fear," vaccine misinformation, deteriorating patient-provider relationships, and severe structural barriers, culminating in an "Ubuntu Paradox" where communal solidarity is undermined by a system that individualizes the financial and logistical burdens of care.

Tsungai Rumbidzai Nondo, Emmanuel Omondi Odera, Tendai Charirity Nhenga, Ngonidzashe Mutanana2026-07-16
📄 medicine

Bentall Procedure in Small Aortoannular Complex: Impact of Implantation Plane on Prosthesis Upsizing and Early Outcomes

In patients with a small aortoannular complex undergoing the Bentall procedure, the subannular-supported supra-annular conduit implantation (SSSC) technique facilitates greater prosthesis upsizing and higher indexed effective orifice area with reduced prosthesis-patient mismatch compared to the supra-annular-supported annular conduit implantation (SSAC) approach, despite distinct complication profiles and similar mortality rates.

Ünsal Vural, Yiğit Köse, Halil Emre Özlu2026-07-16
📄 medicine

Trajectories of Body Weight and Nutrition Support Utilization During Definitive Concurrent Chemoradiotherapy for Esophageal Cancer and Their Association With Treatment Tolerance: A Retrospective Cohort Study

This retrospective cohort study of 286 esophageal cancer patients undergoing definitive chemoradiotherapy identifies three distinct longitudinal trajectories of body weight and nutrition support, revealing that an "early sustained deterioration" pattern is significantly associated with increased risks of treatment delays, prolonged radiotherapy duration, severe acute toxicity, and unplanned hospitalizations.

Min Sheng, Ling Li, Ling Song, Hui Yu2026-07-16
📄 medicine

Fireplace-Related Injuries in Children with Special Emphasis on Neurotrauma: A Retrospective Study from a Paediatric Tertiary Care Centre in the United Kingdom

This retrospective study of 15 children at a UK tertiary care center reveals that fireplace-related injuries, primarily caused by structural collapse, frequently result in severe multisystem trauma and neurosurgical complications, underscoring the critical need for mandatory fireplace anchorage and targeted caregiver safety education to prevent these fatal accidents.

Yashvinder Kumar, Manish Joseph Mathew, Kush Bhatt, Milan Makwana, Jonathan Ellenbogen, Chris Parks, Vejay Vakharia, Aja (…)2026-07-16
📄 medicine

Reproductive and sexual health challenges in Iranian adolescents: a qualitative study

This qualitative study identifies diverse reproductive and sexual health challenges facing Iranian adolescents, ranging from individual behaviors to systemic barriers, while highlighting the urgent need for culturally and religiously sensitive policy interventions to address the current neglect in providing essential information and services.

forough farzollahpour, shahrbanoo salehin, reza chaman, tahere jalali2026-07-16
📄 medicine

Epidemiologic Burden of Depressive Episode and Suicidal Ideation Among Older Lesbian, Gay, and Bisexual Adults: A Five-Year National Survey Study

This five-year national survey study reveals that older lesbian, gay, and bisexual adults, particularly bisexual individuals, experience a disproportionate burden of major depressive episodes and suicidal ideation compared to their heterosexual peers, with these mental health indicators worsening significantly during the COVID-19 pandemic.

Alex Siu Wing Chan, Asiamah Nestor, Florence Wong, Rayner Kay Jin Tan2026-07-16
📄 medicine

Effects of combined intraoral and extraoral low-level laser therapy on postoperative complications after impacted mandibular third molar extraction: A randomized clinical trial

This randomized clinical trial demonstrates that combined intraoral (660 nm) and extraoral (808 nm) low-level laser therapy significantly reduces postoperative pain and swelling following impacted mandibular third molar extraction, though it showed no significant effect on trismus or dry socket incidence.

Hasan Momeni, Mehdi Abrishami, Hanie Chitsaz Zadeh, Ilia Abrishami2026-07-16