📄 medicine

Systematic post-publication accuracy assessment in medical educational content: development and pilot validation of a five-category taxonomic framework

This paper presents the development and pilot validation of a five-category taxonomic framework for systematic post-publication accuracy assessment of medical educational content, demonstrating its strong validity and effectiveness in identifying and resolving errors across diverse resources to address a critical gap in medical education quality assurance.

Mohammed W Abdullah2026-07-16
📄 medicine

Efficacy and safety of postoperative analgesia for intercostal catheterization guided by thoracoscopy in single port thoracoscopic surgery: a prospective randomized controlled trial

This prospective randomized controlled trial demonstrates that thoracoscopy-guided intercostal catheterization with ropivacaine provides postoperative analgesia comparable to intravenous opioid PCA in single-port VATS patients, while significantly reducing opioid-related adverse effects such as dizziness and pump discontinuation without increasing complications or costs.

Kexin Li, Jie Li, Jie Gao, Yongcheng Li, Lihua Han, Lin Ma, Peng Liang2026-07-16
📄 medicine

Stepwise Enhancement of HPV16 E6/E7 mRNA Vaccine Efficacy Using HSV-1 gD Epitope Incorporation and Immune-Modulating Agents

This study demonstrates that the therapeutic efficacy of an HPV16 E6/E7 mRNA vaccine against tumors is significantly enhanced by incorporating a ubiquitin tag and a heterologous HSV-1 gD epitope to boost antigen presentation and T-cell help, with further improvements achieved through combination with immunomodulatory agents like entinostat or ADU-S100.

Kyle Johnson, Jane Jingting Lim, Wanfu Wu, Nguyet Tu, Shaun Xiaoliu Zhang2026-07-16
📄 medicine

Management and Outcomes in Traumatic Cerebral Venous Sinus Thrombosis

This retrospective single-center study of 138 patients with traumatic cerebral venous sinus thrombosis (tCVST) reveals a 10.9% in-hospital mortality rate and suggests that while anticoagulation is associated with lower mortality in patients with less severe injuries, it does not significantly improve sinus recanalization rates, highlighting the need for further investigation into optimal management strategies given the condition's rarity and complex confounders.

Tom E Richardson, Anna H Balabanski, Jasmine Moses, Blake Colman, Leonid Churilov, Robert Whiriskey, Anthony Kam, Joseph (…)2026-07-16
📄 medicine

Seroprevalence of neglected tropical diseases, arboviruses, vaccine-preventable diseases, and enteric protozoa from a national multi-pathogen serosurvey in Niue

A 2025 national multi-pathogen serosurvey in Niue utilized integrated serosurveillance to reveal low neglected tropical disease prevalence, high measles and rubella immunity, declining diphtheria and tetanus protection with age, and significant dengue and Cryptosporidium exposure, demonstrating the method's utility for guiding targeted public health strategies in Pacific Island settings.

Harriet L S Lawford, Grizelda Mokoia, Patricia Tatui, Misiona Nicolas, Andy Manu, Amanda Murphy, Tonia Marquardt, Leanne (…)2026-07-16
📄 medicine

Associations of Sports Behavior Risks and Physical Activity Levels with Adolescent Scoliosis and Related Influencing Factors: a school-based cross-sectional study in China

This school-based cross-sectional study of nearly 9,500 Chinese adolescents reveals that scoliosis is significantly associated with female sex, higher grade levels, lower BMI, and specific sports behavior risks, while highlighting that higher levels of moderate-to-vigorous physical activity and lower sedentary time are protective factors.

Yuanyuan Cao, Xiaohan Li, Shaochun Shi, Yuna Wu, Mengjia Feng, Xu Liu, Xinfeng Zheng, Weibing Wu, Jun Xia2026-07-16
📄 medicine

Social anxiety, BMI and cardiorespiratory fitness among schoolchildren: a cross-sectional serial mediation analysis of cognitive reappraisal and sport engagement

This cross-sectional study of 1,108 Beijing schoolchildren reveals that social anxiety is indirectly associated with higher BMI and lower cardiorespiratory fitness through a serial mediation pathway involving reduced cognitive reappraisal and decreased sport engagement, rather than through direct links.

Yameng Li, Dingye Song, Tianzeng Shao2026-07-15
📄 medicine

Effects of sixteen weeks of two high-intensity flexibility training methods (dynamic versus static) on joint range of motion (ROM) in older adults: a comparative quasi-experimental study

This quasi-experimental study found that after sixteen weeks, high-intensity static mat-based flexibility training significantly improved cervical rotation and hip extension range of motion in older adults and was superior to stick-assisted dynamic training for hip extension, while both methods led to reductions in certain shoulder and hip movements.

Ronaldo Vivone Varejão, Karollyni Bastos Andrade Dantas, Fabio Henrique De Freitas, Everton dos Santos Araújo, Carlos So (…)2026-07-15