📄 medicine

An EHR Data Passport for Renal-Risk AI: Cross-Database Transportability of Creatinine-Based AKI Prediction in Intensive Care

This study introduces an EHR data passport framework to evaluate the cross-database transportability of creatinine-based AKI prediction models between MIMIC-IV and eICU, revealing that while discrimination remains stable, significant differences in data computability, laboratory coverage, and calibration shifts necessitate rigorous pre-deployment stress testing and algorithmic vigilance.

Xiaoxi Zhang, Shaonan Wang, Giselle Chan, Lixin Yin2026-07-01
📄 medicine

Healthcare Ethics Literacy in Pre-Conflict Sudan: A Multi- Disciplinary Institutional Baseline Study from a Tertiary Hospital (2013–2014)

This 2013–2014 study of Sudan's Soba University Hospital reveals a profound systemic failure in healthcare ethics literacy, where despite universal undergraduate ethics training, 66% of frontline clinical providers demonstrated inadequate knowledge of core ethical principles and codes, highlighting a critical knowledge-attitude paradox that serves as a vital pre-conflict baseline for future health system reconstruction.

Algasim Abdelfrag, Muna F. Shaheen2026-07-01
📄 medicine

Efficacy of resistance vs. aerobic training for sarcopenia in cirrhotic patients: a systematic review

This systematic review of seven randomized controlled trials concludes that supervised physical exercise, particularly resistance training, is a safe and effective intervention for improving functional capacity and muscle strength in patients with liver cirrhosis, although evidence regarding muscle mass gains remains limited by protocol heterogeneity.

Priscila Meireles Calil Fontana, Rafael dos Santos Souza, Manuella Franco Cerqueira da Silva, Anete da Costa Medeiros, Y (…)2026-07-01
📄 medicine

Bacterial Spectrum, Antibacterial Resistance and Microbial Dysbiosis Among Cervical Cancer Patients and Their Associated Risk Factors: A Cross-Sectional Study in the Oncology Clinic, National Hospital, Abuja, Nigeria.

This cross-sectional study conducted at a tertiary hospital in Abuja, Nigeria, reveals a high prevalence (84.9%) of diverse bacterial infections with significant antibiotic resistance patterns among cervical cancer patients, highlighting the critical need for routine microbiological surveillance to manage dysbiosis and optimize treatment outcomes.

Chiamaka Ukamaka Oka, Marie-Esther Uju Dibua, Chinedu Simeon Aruah, Oka Ugochukwu Ezeabia, Rita Ngozi Nweke, John Anthon (…)2026-07-01
📄 medicine

Functional outcomes after megaprosthesis for neglected proximal femur pathological fractures: a retrospective case series

This retrospective case series of 12 patients demonstrates that surgical reconstruction using a modular megaprosthesis significantly improves functional mobility and reduces pain in individuals with neglected proximal femur pathological fractures, offering valuable insights for a clinical scenario lacking standardized management protocols.

Joaquim Soares do Brito, Catarina Massano, Francisco Serra Alves, André Spranger, Paulo Almeida, José Portela2026-07-01
📄 medicine

Predicting tuberculosis treatment relapse among geriatric patient using machine learning algorithms in a high Tuberculosis-burden Ghanaian setting.

This study demonstrates that a Random Forest machine learning model outperforms SVM, DNN, and Logistic Regression algorithms in predicting tuberculosis treatment relapse among geriatric patients in Ghana with 99% accuracy, leading to recommendations for its pilot integration into local clinic workflows and improved data-sharing policies.

Michael Aidoo, Rose-Mary Owusuaa Mensah2026-07-01
📄 medicine

Uncemented bipolar hemiarthroplasty with trochanteric clip and cable stabilisation as primary treatment for unstable intertrochanteric fractures in elderly patients with major comorbidities

This study demonstrates that uncemented bipolar hemiarthroplasty with trochanteric clip and cable stabilisation is an effective primary treatment for unstable intertrochanteric fractures in elderly patients with significant comorbidities, enabling early mobilization and achieving an 84.78% success rate at six months.

Muhammad Imran Javed, Muhammad Saad Bin Arshad Arain, Barbara Pierre Louis, Hooria Imran, Athar Zuberi, Niaz Hussain Kee (…)2026-07-01
📄 medicine

Improving discharge planning from acute inpatient mental health care settings: a realist review

This realist review synthesizes evidence from 77 documents and stakeholder input to reveal that achieving person-centred, collaborative discharge planning in acute mental health care requires a system-wide approach to address how macro-level factors like underinvestment and risk-averse cultures reinforce meso-level practices that inhibit micro-level relational care.

Melanie Handley, Corinna Hackmann, Lisa Marie Grünwald, Emma Kaminskiy, Charlotte Wheeler, Hannah Zeilig, Athena Sideri (…)2026-07-01
📄 medicine

Epidemic Keratoconjunctivitis in Conflict-Affected Kassala, Sudan (2024–2025): A Qualitative Exploration of Community Experiences and Health System Response

This qualitative study conducted in conflict-affected Kassala, Sudan, reveals how epidemic keratoconjunctivitis is exacerbated by health system fragility, socioeconomic barriers, and reliance on informal remedies, underscoring the urgent need for decentralized, community-coordinated eye care interventions.

Ibrahim Ibrahim, Abubakar Jibo, Fatima Sharif, Shawgi Adugory, Ebtisam Duffuaa, Manal Azrag, Razan Awadelkareem, Abdelra (…)2026-07-01
📄 medicine

Estimated Burden of Childhood Wheeze and Asthma Attributable to Infant RSV Lower Respiratory Tract Infection in the United States

This study estimates that approximately 11.1% of childhood wheeze and asthma cases in the United States are attributable to infant RSV lower respiratory tract infections, suggesting that a national nirsevimab program could prevent nearly 10,000 such cases annually.

Ian M. Galbreath, David W. Hutton, Allison M. LaRocco, Steven M. Brunwasser, Brittney M. Snyder, Amanda J. Driscoll, Pin (…)2026-07-01