13473 papers
This retrospective cohort study using MIMIC-IV data reveals that red blood cell transfusions administered within the first 24 hours after cardiac surgery are significantly associated with an increased risk of subsequent ICU delirium, with the risk rising in a dose-dependent manner.
This descriptive cross-sectional study evaluating Rwanda's cervical cancer surveillance system in Kigali City from January 2023 to June 2025 found that the system performs well to very well across key attributes like data quality and timeliness, though its overall effectiveness is currently limited by high loss to follow-up among HPV-positive women and moderate system flexibility.
A survey of 89 adult cancer patients at a tertiary center reveals that while the vast majority find opioid treatment agreements clear, relevant, and protective of their safety, a significant minority (28%) still harbor concerns or questions, highlighting the need for improved communication and education regarding these tools.
In a peri-urban LMIC context, this Drakenstein Child Health Study sub-study found that higher maternal depression significantly predicts lower sensitive engagement, while some factors typically associated with sensitivity in high-income countries did not show similar effects in this high-risk setting.
This prospective study of 45 non-Hodgkin's lymphoma patients undergoing CHOP chemotherapy demonstrates that early increases in serum hs-TnT and sST2 levels, particularly when combined, serve as significant predictors of chemotherapy-induced cardiac arrhythmia.
This retrospective cohort study of 240 patients suggests that immediate curettage following medically induced second-trimester abortion does not significantly reduce the risk of pathologically confirmed retained products of conception or improve short- and long-term maternal outcomes compared to conservative management, although the findings are limited by the study's non-randomized design.
This exploratory study of 26 patients suggests that combining the neutrophil-to-lymphocyte-to-platelet ratio (NLPR) with prostate volume may offer preliminary, though unvalidated, utility in distinguishing between Gleason 3+4 and 4+3 prostate cancers, warranting further investigation in larger cohorts.
This single-center retrospective study characterizes a growing, geographically diverse population of surgical candidates who decline cholecystectomy in favor of organ preservation, demonstrating that the GO-SCOPE procedure provides durable 12-month symptom relief with a favorable safety profile for patients with symptomatic cholelithiasis.
This mixed-methods study in Homa Bay County reveals that Kenya's 2024 transition from free maternity care to Social Health Insurance (SHIF) has reproduced and amplified existing inequities in maternal healthcare access, particularly for adolescents, unemployed women, and users of lower-level facilities, due to barriers in timely enrolment, persistent out-of-pocket costs, and limited facility reimbursement.
This systematic review and meta-analysis of 11 studies involving 296 patients with AR-positive triple-negative breast cancer indicates that while AR pathway-targeted therapies yield limited tumor shrinkage (5.4% ORR), they provide durable disease control in approximately one-third of patients, though these findings are tempered by the reliance on small, single-arm trials with inconsistent definitions.