3171 papers
This pilot study demonstrates that combining varenicline with a behavioral intervention targeting both smoking cessation and pain management is feasible, acceptable, and preliminarily effective for helping patients with cancer quit smoking, though further refinement is needed to improve pain management outcomes.
This paper introduces the Student-Nurse Educator Interactive Model (SNEIM), a contextually grounded middle-range theory developed through mixed-methods research in Malawi to guide the acquisition of clinical reasoning skills in undergraduate nursing students by integrating six key themes into five interdependent anchors within a conducive clinical environment.
This paper presents a four-year cost analysis of a dementia patient and carer Public Advisory Board, revealing that while PPI is resource-intensive with design and implementation as the primary cost drivers, early and deep community engagement ultimately enhances financial efficiency and ensures meaningful participation.
This retrospective study demonstrates that three monthly intravitreal conbercept injections significantly improve visual acuity, reduce retinal and choroidal thickness, and enhance superficial and deep capillary plexus perfusion in patients with diabetic macular edema.
This study developed a SARIMA(3,0,2)(1,0,1)[52] predictive model using routine weekly data to forecast Lassa fever outbreaks in Ondo State, Nigeria, successfully identifying seasonal peaks between weeks 48 and 52 to guide proactive public health interventions and resource allocation.
This study identifies TMEM45A as an independent poor prognostic biomarker in gastric cancer that drives tumor progression by physically interacting with P4HA1 to elevate succinate levels and activate the TGF-β/Smad signaling pathway.
This study demonstrates that a poloxamer-based intranasal clozapine sol-gel formulation achieves long-term antipsychotic effects in rats at just 4% of the oral therapeutic dose while potentially mitigating gut microbiome disruption associated with oral administration.
This prospective study conducted in a Nepalese tertiary care hospital demonstrates that serum Golgi Protein 73 (GP73) is a highly accurate noninvasive biomarker for distinguishing advanced chronic liver disease and severe fatty liver disease from early-stage fatty liver, outperforming conventional markers like FIB-4 and APRI.
This cross-sectional study analyzing three rounds of Liberia Demographic Health Survey data (2007–2019) reveals a concerning upward trend in unintended pregnancies among reproductive-age women, particularly adolescents, driven by factors such as unmet family planning needs, low modern contraceptive use, and specific demographic characteristics.
This descriptive cross-sectional study of 422 chronic kidney disease patients in Sri Lanka reveals that poor sleep quality and frequent distressing dreams, particularly nightmares, are prevalent and independently associated with higher levels of psychological distress, underscoring the need for routine screening of sleep and dream characteristics in nephrology care within low- and middle-income countries.