📄 medicine

Modified Percutaneous Vertebroplasty with Bilateral Cannulated Screws and Staged Cement Injection for Stage I and II Kummell’s Disease: A Mid-to-Long Term Follow-Up Study

This mid-to-long term follow-up study demonstrates that a modified percutaneous vertebroplasty technique utilizing bilateral cannulated screws, steerable cement delivery, and staged injection is a safe and feasible treatment for Stage I and II Kummell's disease, providing sustained pain relief, functional improvement, and durable vertebral height restoration while minimizing complications like cement loosening and re-collapse.

Huimin Wang, Xiaofeng Li, Wei Du, Xuri Sun, Haiqing Tian, Dexin Zou2026-06-28
📄 medicine

Retrospective observational study comparing profile of steroid-sensitive nephrotic patients on alternate day versus daily levamisole therapy.

This retrospective study suggests that while both alternate-day and daily levamisole therapies are effective for steroid-sensitive nephrotic syndrome in children, daily therapy may be a preferable alternative for younger patients who fail alternate-day treatment, as they experience earlier first relapses on the alternate-day regimen.

Anubha Shrivastava, Ranjana Singh, Shahid Akhtar Siddiqui, Santosh Kumar Shukla, Ishita Vashisth2026-06-28
📄 medicine

The Academic Use of Artificial Intelligence Tools Among First-Year Medical Students: A Cross-Sectional Online Survey

This cross-sectional survey of first-year medical students in Türkiye reveals that while AI tools like ChatGPT are widely adopted for studying and understanding course content, students recognize the necessity of verifying AI-generated information, underscoring the need to integrate AI literacy and critical appraisal into undergraduate medical education.

Handan Duman2026-06-28
📄 medicine

Development of a machine learning-based prediction model for objective indications for renal replacement therapy after stage 3 acute kidney injury

This study developed and externally validated a machine learning model using routinely collected clinical variables to predict the short-term risk of objective indications for renal replacement therapy within 24–72 hours after stage 3 acute kidney injury, demonstrating promising discrimination but highlighting the need for local recalibration before clinical implementation.

Chaodong Chen, PengChao Tian, Xin Chen, FangXing Guo, WenXiong Li2026-06-28
📄 medicine

Supporting Implementation of the National Standards for Cancer Survivorship Care: Development of the Cancer Survivorship Maturity Model (CSMM)

This study describes the development and preliminary evaluation of the Cancer Survivorship Maturity Model (CSMM), a seven-domain framework designed to assess organizational readiness for implementing national cancer survivorship care standards and to identify specific gaps and barriers to improvement.

Heidi Dowst, Maryem Shirzadi, Martha Mims, Susan Hilsenbeck, Liwei Wang, Hoda Badr2026-06-28
📄 medicine

Ocular Injuries among the Civilian Palestinian Population during the war on Gaza, March–September 2025: A Hospital-Based Observational Study

This retrospective observational study of 1,891 civilian patients in Gaza from March to September 2025 reveals that ocular injuries were predominantly severe, blast-related open-globe traumas with a high burden of irreversible visual loss, disproportionately affecting children and necessitating extensive surgical interventions.

Mohamed Rashad, Iyad Abukaresh2026-06-28
📄 medicine

Prefrontal Circuitry Abnormalities and Cognitive Impairment in Adolescents with Early- Onset Psychosis

This study demonstrates that cognitive impairment in adolescents with early-onset psychosis is linked to convergent abnormalities in dorsolateral prefrontal cortex function, fronto-striatal connectivity, and fronto-cerebellar structure, supporting a model of disrupted prefrontal circuit maturation.

Hanne Van Der Heijden, Saad Rahmat, Amanda Cao, Raquel van Gool, Merve Koç Yekedüz, Lise Vrolix, Talia Barrett, Edin T. (…)2026-06-28
📄 medicine

Time-to-Event Analyses of UPDRS and MDS-UPDRS Motor Examination and Functional Outcomes in Early Parkinson’s Disease Clinical Trials

This study analyzes five early Parkinson's disease trials to demonstrate that time-to-event analyses using large worsening thresholds on motor and functional scales are feasible for detecting meaningful treatment benefits within 12-month clinical studies before treatment initiation.

Andrew McGarry, Christopher R Meyer, Karl Kieburtz, Jordan Dubow, Milton H Werner, Charles Venuto2026-06-28
📄 medicine

Posterior Scleritis With Secondary Uveal Effusion Unmasking Peripapillary Pachychoroid Syndrome

This case report describes a 71-year-old patient with posterior scleritis and secondary uveal effusion who, upon treatment with corticosteroids, revealed a coexisting peripapillary pachychoroid syndrome, highlighting the importance of multimodal imaging in distinguishing these conditions and managing the potential exacerbation of pachychoroid features by steroid therapy.

Victor Alegre-Ituarte, Erika Sanchez-Vela, Esther Cilveti-Gomez, Alba Gomez-Benlloch, Tetiana Goncharova-Simon, Marta La (…)2026-06-28
📄 medicine

The Unsteady Return of Command-Following: Recovery and Instability of Bedside Motor Command-Following After Acute Brain Injury

This study analyzes a large cohort of acute brain injury patients to reveal that while bedside command-following often returns early, its recovery is highly unstable, fluctuates frequently, and is strongly influenced by sedation and injury phenotype, rendering single observations unreliable for assessing consciousness.

Alon Gorenshtein, Yosef Adiniaev, Mahmud Omar, Yiftach Barash, Eyal Klang, Oved Daniel2026-06-28