📄 Category

medicine

6308 papers

📄 medicine

Lateralized Veno-Occlusive Dysfunction in Peyronie's Disease: Bilateral Corporal Hemodynamic Discrepancy Revealed by Dynamic Penile Doppler Ultrasonography in Men With and Without Erectile Dysfunction

This retrospective study of 189 men with Peyronie's disease reveals that those with erectile dysfunction exhibit significant bilateral corporal hemodynamic asymmetry, particularly characterized by reduced left-sided resistive indices, suggesting ipsilateral plaque-mediated veno-occlusive dysfunction that warrants routine bilateral assessment for surgical risk stratification.

Abdullah alzahrani, Mohammed Aleid, Anne Yin, Hend Alshamsi, Jeffrey Sioufi, Mélanie Aubé-Peterkin, Serge Carrier2026-06-28
📄 medicine

Medicine shortages and glaucoma care: a time-series analysis indicating population-level consequences of a national timolol eye drop shortage

A retrospective time-series analysis of Australian dispensing data reveals that the 2024–2025 national timolol eye drop shortage significantly disrupted access to this first-line glaucoma treatment, with imported products providing only partial mitigation and failing to restore utilization to pre-shortage levels despite regulatory approval.

Erin Fawcett, Lisa Kalisch Ellett, Simi Sarin, Cassandra Haines, Helen Stone, Jack Janetzki2026-06-28
📄 medicine

Exhaled Volatile Organic Compounds as Non-Invasive Biomarkers for the Diagnosis, Phenotyping, and Treatment Response Prediction in Asthma

This study demonstrates that exhaled volatile organic compounds (VOCs) serve as effective non-invasive biomarkers for distinguishing asthmatic patients from healthy controls, assessing disease control and phenotypes, and predicting treatment response, thereby offering a promising tool for precision asthma management.

Liang Han, Zhang-qin Chen, Xu-yu Cui, Hong Yan, Ying Kang, Rui-jiang Shi, Ya-meng Sun, Li-qiang Song, Shuo-yao Qu2026-06-28
📄 medicine

Structured postmortem genetic counselling and testing in sudden unexpected death among young adults in the Netherlands: Results and implications regarding hereditary risk

This study demonstrates that implementing a structured multidisciplinary postmortem investigation, specifically the NODOV procedure combining molecular autopsy with genetic counselling, successfully identifies pathogenic variants in sudden unexplained deaths among young adults and enables effective preventive screening for at-risk relatives.

Tess Wemeijer, Leonie Verbaan, Wilma Duijst, Yvonne Hoedemaekers, Imke Christiaans2026-06-28
📄 medicine

Standard Setting in the Era of Workplace-Based Assessment: A Pilot Exploration

This pilot study demonstrates that three established standard-setting methods (Angoff, Bookmark, and Construct Mapping) can be feasibly and reliably adapted to longitudinal workplace-based assessment data to define a defensible general surgery graduation standard, with a proposed cut score of 582 supported by the convergence of results and qualitative insights.

Alyssa A Pradarelli, Kayla M Marcotte, Brian C George, Tyler J Loftus, James R Korndorffer, David T Hughes, Gifty Kwakye (…)2026-06-28
📄 medicine

Predictors of chronic etizolam use among newly treated patients: a 21-year retrospective cohort study

This 21-year retrospective cohort study of over 12,000 patients at a Japanese university hospital reveals that while new etizolam prescriptions have declined, chronic use remains common, with older age, higher initial doses, longer initial prescription durations, and specific department types identified as independent predictors of long-term continuation.

Mutsuhiro Nakao, Hokuto Morohoshi, Yumiko Kurata, Akiou Nakamura2026-06-28
📄 medicine

Metastatic Status as an Independent Predictor of 30-Day Readmission and In-Hospital Mortality in Gastric Cancer–Related Gastrointestinal Bleeding: A Nationwide Readmissions Database Analysis

This nationwide analysis reveals that metastatic status is an independent predictor of significantly higher in-hospital mortality and 30-day readmission rates among patients hospitalized for gastric cancer-related gastrointestinal bleeding, highlighting the urgent need for early palliative care and specialized post-discharge support in this vulnerable population.

Rushi Shah, Ibrahim Azar, Ravi Patel, Rakshana Ravichandran, Aditya Kohli, Camelia Arsene, Muhammad Bilal, Geetha Krishn (…)2026-06-28
📄 medicine

External validation and comparison of PREVENT and SCORE2 atherosclerotic cardiovascular risk scores in the MASHAD cohort study

This study externally validated the PREVENT and SCORE2 cardiovascular risk models in the Iranian MASHAD cohort, finding that while both models demonstrated acceptable discrimination, they significantly underestimated absolute risk and required local recalibration to provide accurate predictions for this Middle Eastern population.

Ali Tajik, Hamidreza Rahimi, Sara Saffar Soflaei, Mohsen Moohebati, Ashkan Bahrami, Gordon A. Ferns, Habibollah Esmaily (…)2026-06-28
📄 medicine

Prediagnostic Plasma Proteomic Signatures and Risk Stratification for Incident Chronic Kidney Disease in Type 2 Diabetes

This study demonstrates that baseline plasma proteomic profiling in adults with type 2 diabetes identifies a biologically interpretable prediagnostic signature of immune and extracellular matrix pathways that significantly improves the risk stratification for incident chronic kidney disease beyond standard clinical variables.

Wenhong Liu, Yuxin Hong, Hao Yan, Zongxin Meng, Huan Zhang, Yue Yuan, Zhiwei Xu, Zhaoxiang Wang, Hui Wang2026-06-28
📄 medicine

Pedicled temporalis muscle flap salvage reconstruction for recalcitrant cerebrospinal fluid leaks following extended endoscopic endonasal approach for pituitary adenomas

This study demonstrates that the pedicled temporalis muscle flap is a reliable and effective salvage reconstructive technique for achieving durable control of recalcitrant cerebrospinal fluid leaks in patients who lack available conventional vascularized intranasal flaps following extended endoscopic endonasal pituitary adenoma surgery.

Zhenye Li, Zehao Xiao, Jiwei Bai, Chunhui Liu, Haibo Zhu, Lei Cao, Sen Cheng, Ding Nie, Songbai Gui, Yazhuo Zhang, Chuzh (…)2026-06-28