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Neuromuscular Electrical Stimulation as an Adjunct to Botulinum Neurotoxin Therapy in Facial Movement Disorders: A Prospective Within- Subject Crossover Study

This prospective within-subject crossover study demonstrates that adjunctive neuromuscular electrical stimulation significantly enhances the clinical efficacy and duration of botulinum neurotoxin therapy for facial movement disorders, offering a well-tolerated strategy to improve symptom severity and prolong symptom-free intervals.

Julia Schubert, Albrecht Günther, Florian Rakers, Orlando Guntinas-Lichius, Carsten M Klingner, Stefan Brodoehl, Gerd Fa (…)2026-06-28

📄 medicine

Comparative 3D Gait Analysis: Impact of Total Hip Arthroplasty Stem Anchoring (Metadiaphyseal vs Metaphyseal)

This prospective randomized study utilizing 3D gait analysis and patient-reported outcomes demonstrates that metaphyseal-stem total hip arthroplasty (MTHA) facilitates quicker gait recovery and yields superior functional scores compared to metadiaphyseal-stem implants (MDTHA) at one year postoperatively.

Jan Cerny, Lucie Loukotova, Marek Jelinek, Jan Soukup, Tomas Novotny2026-06-28

📄 medicine

The Hormone-Brain-Emotion Axis in Endocrine Therapy for Early Breast Cancer: Insights from a Survivorship Cohort

This study of women undergoing adjuvant endocrine therapy for early breast cancer reveals that fatigue and emotional distress are the primary, interrelated drivers of perceived cognitive impairment, suggesting that routine screening and management of these modifiable symptoms are essential for improving survivorship care and treatment adherence.

Tiago Pina-Cabral, Vanessa Branco, Patricia Cavaco, Margarida Lagarto, José Pereira, Helena Miranda, Ana Martins2026-06-28

📄 medicine

Prevalence of obstructive sleep apnoea and validation of the OSA-5 questionnaire among children aged 2-7 years with adenotonsillar hypertrophy at Mulago National Referral Hospital, Uganda: a prospective cross-sectional study

This prospective cross-sectional study at Mulago National Referral Hospital found that obstructive sleep apnoea affects 88.5% of children aged 2–7 with adenotonsillar hypertrophy and demonstrated that the OSA-5 questionnaire achieves perfect sensitivity and specificity in diagnosing the condition within this high-risk population, suggesting its utility for prioritizing care in low-resource settings.

Geoffrey Tabu, Justine Namwagala, Rym Hidour, Hellen T. Aanyu, Ivan Kimuli2026-06-28

📄 medicine

Opioid prescribing practices for dyspnea across palliative care settings: a retrospective observational study

This retrospective observational study at a French university hospital reveals that opioid prescribing practices for dyspnea in palliative care are characterized by substantial variability across different settings, with most patients already on opioids prior to specialist involvement and dose adjustments primarily driven by the need for symptom relief.

Amandine Mathé, Anne-Lise Giffard, Véronique Averous, Camille Saussac, Etienne Rivière, Anais Braverman2026-06-28

📄 medicine

Bariatric Surgery, Weight Loss and Long-Term Coagulopathy; Is There a Link?

This systematic review of 546 post-bariatric patients indicates that long-term weight loss shifts hemostasis from a prothrombotic state to a less coagulable, more fibrinolytic condition, suggesting a potential hidden coagulopathy that warrants further investigation despite the lack of immediate clinical bleeding risk.

Omar A. Bamalan, Abdullah H. Alnasser, Manar Alossaif, Reem Al-Qahtani2026-06-28

📄 medicine

Micronutrient Intake and Dietary Patterns Associated with Cardiometabolic Health Outcomes of Overweight and Obese Pregnant Women in Dodoma, Tanzania

This study in Dodoma, Tanzania, reveals that overweight and obese pregnant women, despite consuming diets linked to both improved hemoglobin and increased cardiometabolic risks, frequently fail to meet micronutrient recommendations and neglect essential supplements.

Jacktan J Ruhighira, Alexander M Tungu, Costantine C Kamata, Elizabeth A John, Davis Ngarashi, Evangelista Malindisa, Fr (…)2026-06-28

📄 medicine

Parents’ Concerns About Endocrine Disruptors in Perinatal Health

This qualitative study conducted in La Réunion reveals that while parents are intuitively aware of endocrine disruptors during the perinatal period, they face significant challenges due to contradictory information and media-driven sources, highlighting an urgent need for reliable, unbiased, and accessible health guidance.

Méryl Méar, Sébastien Leruste, Jessica Dumez2026-06-28

📄 medicine

A Lightweight YOLOv8-Based Diagnostic System for Prostatic Acinar Adenocarcinoma: A Comparative Analysis of Architecture, Performance, and Clinical Applicability

This study presents an open-source, lightweight YOLOv8-based diagnostic system for prostatic acinar adenocarcinoma that achieves high accuracy in Gleason grading and lesion detection while offering a cost-effective, locally deployable alternative to expensive commercial and closed-source AI solutions.

Zihan Lin¹2026-06-28

📄 medicine

Time in Range Predicts Mortality in Severe Subarachnoid Hemorrhage: A Retrospective Cohort Study on the Mediating Role of Inflammation

This retrospective cohort study of 1,594 severe subarachnoid hemorrhage patients demonstrates that higher Time in Range (TIR) is an independent, potent protective factor against short- and long-term mortality, an association partially mediated by reduced systemic inflammation and most pronounced in non-septic patients.

Yuhang Hu, Xuemei Xu, Jian Chen, Jing Xu, Li Tang, Kangxing Wang, Xianmin Wang2026-06-28

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