Evaluation of Substitution of Total Bilirubin by Direct Bilirubin in Prediction of Mortality Models in patients with acute and Acute-on-chronic liver failure
This prospective observational study demonstrates that substituting total bilirubin with direct bilirubin in mortality prediction models (such as AARC, MELD, and MELD-Na) significantly enhances prognostic accuracy for patients with acute-on-chronic liver failure and offers comparable benefits for those with acute liver failure.