📄 Category

medicine

6374 papers

📄 medicine

Triglyceride-Glucose Index and Dysglycaemia in Adults from the Aral Sea Region of Uzbekistan: Associations with Thyroid Function and Elevated Aminotransferases

In a cross-sectional study of adults from the environmentally vulnerable Aral Sea region of Uzbekistan, the Triglyceride-Glucose (TyG) index was identified as a practical and significant marker for dysglycaemia, while elevated aminotransferases were linked to metabolic risk and thyroid dysfunction appeared more closely associated with central adiposity than with glycaemic status.

Zinegul Ainazarova, Telman Kamalov, Anna Alieva, Zulaykho Shamansurova2026-06-28
📄 medicine

Erythropoietic Protoporphyria Life Impact and Genetic Health Trajectory (LIGHT) Study in Europe: A Cross-Sectional Online Questionnaire

This European cross-sectional study reveals that erythropoietic protoporphyria significantly impairs patients' daily lives, work productivity, and emotional well-being due to frequent, severe photosensitivity reactions, underscoring the urgent need for early diagnosis and effective treatments.

Hetanshi Naik, Kristen Wheeden, Susan D. Mathias, Chelsea Norregaard, Adaeze Q. Amaefule, Melanie Chin, Manisha Balwani2026-06-28
📄 medicine

Influence of paediatric overweight and obesity on emergence delirium: a prospective, observational cohort study

This prospective observational cohort study of 230 children undergoing elective non-cardiac surgery found that overweight and obese patients have a significantly higher incidence of emergence delirium compared to their normal-weight counterparts, despite no observed differences in postoperative pain or behavioral changes.

Ke-xin Yi, Ming-cheng Du, Guan-chao Qin, Xiang Long, Jing-jing Jiang, Yuan Gong2026-06-28
📄 medicine

Analysis of Influencing Factors and Construction of Risk Prediction Model for Abnormal Glucose Tolerance in Postpartum Women with Gestational Diabetes Mellitus

This retrospective cohort study of 326 postpartum women with gestational diabetes mellitus identified pre-pregnancy BMI, excessive pregnancy weight gain, poor prenatal blood glucose control, insulin use, and advanced maternal age as independent risk factors for abnormal glucose tolerance 6–12 weeks after delivery, and successfully constructed a predictive model with an AUC of 0.82 to facilitate early clinical intervention.

Chunya Huang, Jia Xu2026-06-28
📄 medicine

Preoperative Triple Inhalation Therapy in Patients with Non–Small-Cell Lung Cancer and Emphysema: Impact on Postoperative Complications

This retrospective study suggests that preoperative triple inhalation therapy (LAMA/LABA/ICS) may reduce postoperative pulmonary complications in patients with non-small-cell lung cancer and emphysema, even among those with more severe underlying lung disease, without increasing adverse events.

Atsushi Kagimoto, Masaya Otabe, Takeshi Mimura2026-06-28
📄 medicine

Effects of cardiomyopeptidin on myocardial injury in ICU patients: a prospective randomized controlled pilot study

This prospective randomized controlled pilot study suggests that cardiomyopeptidin (CMP) may significantly reduce the incidence of major adverse cardiac events and lower specific cardiac biomarkers in critically ill patients with myocardial injury, warranting further investigation into its therapeutic potential.

Jingyi Liang, Jindai Yang, Yizun Qiao, Le Chang, Yuhang Yan, Xiangning Zhong, Bingxuan Geng, Junying Bao, Zhongqing Chen (…)2026-06-28
📄 medicine

Comparison of Polymyxin B with Minocycline versus Polymyxin B with High-Dose Sulbactam in Carbapenem-Resistant Acinetobacter baumannii Ventilator-Associated Pneumonia: A Randomized Double-Blind Non-Inferiority Trial

This randomized double-blind non-inferiority trial demonstrates that the combination of polymyxin B and minocycline is clinically non-inferior to polymyxin B plus high-dose sulbactam for treating carbapenem-resistant *Acinetobacter baumannii* ventilator-associated pneumonia, offering a viable therapeutic alternative in settings with prevalent sulbactam resistance.

Parimal Chintala, Ashwini A Kundar, Bharat Yalla, Ganga Prasad, Souvik Maitra, Rahul Kumar Anand, Babita Gupta, Kapil De (…)2026-06-28
📄 medicine

Diagnostic Pitfalls and Management Patterns of Pediatric Right-Sided Colonic Diverticulitis: A Single-Center Retrospective Study

This single-center retrospective study of 26 pediatric patients highlights that right-sided colonic diverticulitis is a rare condition with nonspecific symptoms often misdiagnosed as appendicitis, yet it generally presents with milder inflammation than complicated appendicitis and can be effectively managed with observation or conservative surgery to avoid unnecessary diagnostic pitfalls.

Hao Shi, Jing Xiong, Qiongqiong Ji, Xiang Ren, Jiangbin Liu, Zhibao Lv, Haifa Hong, Ting Xu2026-06-28
📄 medicine

DCE-MRI Radiomics-Based Tumor Habitat Analysis for Three-Class Prediction of HER2 Expression Status in Breast Cancer

This study demonstrates that a machine learning model integrating DCE-MRI radiomics-based tumor habitat analysis with clinical variables can effectively and non-invasively predict three-class HER2 expression status in breast cancer, achieving a test set micro-average AUC of 0.865.

Wei Guo, Shunan Che, Xiaohua Wang, Qianhua Chen, Yao Yao, Huimiao Chen, Yong Cheng, Shi Tan2026-06-28
📄 medicine

Clinical characteristics and risk factors in dry eye disease secondary to chronic graft-versus-host: A Comparative Cross-Sectional Study

This comparative cross-sectional study reveals that dry eye disease secondary to chronic graft-versus-host disease exhibits more severe ocular surface damage, meibomian gland loss, and degraded visual quality than non-cGVHD dry eye, with specific transplant-related factors such as acute myeloid leukemia and haploidentical HLA matching serving as significant predictors of severity.

Danna Chen, Shitong Huang, Jinyu Zhang, Jinqi Huang, Yu Jiang, Caihong Pang, Simin Wen, Honghua He, Yanhua Pang, Yunxia (…)2026-06-28