📄 medicine

Attitudes And Practices Towards Postoperative Complication Management Among Nurses In Federal Teaching Hospital, Ido Ekiti: A Mixed-Methods Study

This mixed-methods study at a Nigerian tertiary hospital reveals that while nurses possess high knowledge and positive attitudes toward postoperative complication management, their actual practice is strongly driven by attitude rather than knowledge and is significantly hindered by systemic barriers such as staff shortages, resource limitations, and patient financial constraints.

Owolabi Babajide Augustine, Bamise Paul Adedayo, Aina Olugbenga Oluwole, Agbetayo Kehinde Oke, Oloruntimilehin Oyindamol (…)2026-10-23
📄 medicine

ADHD in Pregnancy: Prevalence and Demographic Changes from 2016-2025

This study utilizing the Epic Cosmos dataset reveals that ADHD diagnoses among pregnant women in the United States rose exponentially from 2016 to 2025, with the highest prevalence observed in White patients and a significant increase in diagnoses among those aged 35 or older, highlighting the urgent need to evaluate the impact of this growing trend on maternal and neonatal outcomes.

Ryan Benoy, William Park, Zachary Stowe2026-10-23
📄 medicine

Divergent Shifts in Paediatric Emergency Care Before, During, and After the COVID-19 Pandemic: An Interrupted Time Series Analysis

This interrupted time series analysis of over 13 million paediatric emergency department visits in Ontario reveals that while overall visit volumes largely recovered following the initial severe pandemic decline, the proportion of urgent cases has significantly increased, indicating a fundamental shift in how children utilize emergency care.

Chutong Liu, Anna Gunz, Rodrick Lim, Anne Hicks, Eric Lavigne, Piotr Wilk2026-10-23
📄 medicine

On-Water Prescribed Training Intensity Distribution and Ability-Related Training Composition in Elite Junior Male Canoe Sprint Athletes Preparing for the 2025 ICF Junior Canoe Sprint World Championships: An Observational Case Study

This longitudinal observational case study characterizes the phase-specific organization of on-water training volume, prescribed intensity distribution, and ability-related composition in an elite junior male canoe sprint squad preparing for the 2025 ICF World Championships, revealing a predominantly pyramidal intensity pattern and aerobic-focused training structure while explicitly noting that these findings describe the specific squad's regimen rather than proving its effectiveness.

Qihao Sun, Yin Yu, Jusheng Xu, Jianheng Wei, Jiayue Cui, Simin Lin, Xiaohan Wang, Yukun Li, Chenxu Dan, Tian Zhou2026-10-23
📄 medicine

Assessment of Intra-Household Tuberculosis Transmission: Predictors and Correlates of Risk Factors in India

This study utilizing India's NFHS-5 data reveals that intra-household tuberculosis transmission is significantly driven by intersecting socioeconomic, demographic, and environmental factors—particularly poverty, overcrowding, and behavioral risks—underscoring the need to shift from individual case management to household-centric, socially stratified surveillance and structural interventions.

Arun Kumar Yadav, Sapana Ngangbam, Vidya Yadav2026-10-23
📄 medicine

Coagulopathy subphenotypes and mortality in critically ill patients with sepsis: a multicentre retrospective cohort study using MIMIC-IV and SICdb

This multicentre retrospective study utilizing consensus clustering on MIMIC-IV and SICdb data identifies three reproducible sepsis-induced coagulopathy subphenotypes, revealing that while pan-coagulopathy consistently predicts higher mortality, isolated aPTT prolongation serves as a high-risk marker specifically in surgical ICU and SIC-positive settings, thereby supporting phenotype-informed prognostication and future trial design.

Yongsheng Shi, Qiaoqiao Fang, Huan Bai, Ning Tang2026-10-23
📄 medicine

A Randomized, Double-Blind, Non-Inferiority Trial Comparing a Novel Single-Use Adjunctive Defecation Device Versus Manual Disimpaction Therapy for the Management of Refractory Fecal Impaction Secondary to Outlet Obstruction in Patients with Chronic Constipation

This randomized, double-blind, non-inferiority trial demonstrates that a novel single-use digital assisted defecation device (DDAD) is non-inferior to manual disimpaction in achieving complete clearance of refractory fecal impaction while offering significant advantages in reduced pain, shorter procedure time, and fewer adverse events.

Jianhua Zhang, Qiang Guo, Lei Tang, Zhaojing Yuan, Jianguo Hao, Guofu Zuo, Peng Li, Ping Yan, Jing Cai, Mingzheng Zhang2026-10-23
📄 medicine

Building a selective dorsal rhizotomy service in Shanghai: a retrospective evaluation of one team across two public tertiary children's hospitals, 2015 – 2026

This retrospective study of 1,312 patients across two Shanghai hospitals demonstrates that a single surgical team successfully sustained a high-volume selective dorsal rhizotomy service with a national catchment, while using adverse event data to identify and correct a technical cause of transient weakness and highlighting a significant documentation gap regarding reasons for non-surgical referrals.

Bo Xiao, Jiaqi Feng, Yiying Li, qijia zhan, Wenbin jiang, Rong Mei, Yunhai Song, Min Shen2026-10-23
📄 medicine

Social support and healthcare navigation in later life: Instrumental and cognitive pathways among native-born and migrant older adults

This study of 1,332 older adults in Switzerland reveals that while social support facilitates healthcare navigation through both instrumental and cognitive pathways for both native-born and migrant populations, migrants face greater barriers due to fewer resources, highlighting the need for community interventions that expand networks and train relatives to improve health literacy.

Paolo Martinelli, Francesca Bosisio, Dario Spini2026-10-23
📄 medicine

Interleukin-6 as an Inflammatory Biomarker of Thyroid Dysfunction in Patients Undergoing Maintenance Hemodialysis: A Cross-Sectional Study

This cross-sectional study of 65 maintenance hemodialysis patients demonstrates that elevated serum Interleukin-6 is independently associated with reduced total T3 levels and shows moderate discriminatory ability for thyroid dysfunction, suggesting its potential utility as a practical inflammatory biomarker in this population.

Sony Wibisono Mudjanarko, Fauziah Diayu Retnaningtyas, Puguh Oktavian, Mochammad Thaha, Artaria Tjempakasari, Dananti Ku (…)2026-10-23