📄 Category

medicine

13396 papers

📄 medicine

Prognostic value of blood urea nitrogen-to-albumin and C-reactive protein-to-albumin ratios in acute stroke compared with established clinical and radiological predictors: a single-center retrospective cohort study

This single-center retrospective study of 736 acute stroke patients found that while the C-reactive protein-to-albumin ratio (CAR) showed a modest independent association with in-hospital mortality, both CAR and the blood urea nitrogen-to-albumin ratio (BAR) demonstrated limited discriminatory performance compared to established clinical and radiological predictors like lesion volume and stroke severity scores.

Muhammet Raşit Özer, İsmail Buğra Bilen, Enes Bayındır, Kadir Küçükceran, Sami Ataman, Hasan Hüseyin Kır, Mustafa Altaş2026-10-23
📄 medicine

Preoperative systemic inflammation in pelvic chondrosarcoma: prognostic associations and limited incremental value beyond clinicopathological factors

This retrospective study of 110 patients with pelvic chondrosarcoma found that while preoperative systemic inflammatory markers (mGPS, CAR, and NLR) were independently associated with overall survival, they offered only limited incremental prognostic value beyond established clinicopathological factors.

Mingzhong Xiao, Xiang Fang, Hui Dong, Yan Xiong, Senlin Lei, Fuguo Kuang, Wenli Zhang, Hong Duan2026-10-23
📄 medicine

Spirituality and psychological orientation in women with obesity in India: Associations with mental well-being and quality of life

This cross-sectional study of 65 Indian women with obesity reveals that higher levels of spirituality are significantly associated with better mental well-being, a more positive psychological orientation, and improved quality of life, suggesting that integrating spiritual perspectives could enhance holistic care for this population.

Richa Randhawa, Ashwin Mathur, Arundeep Randhawa2026-10-23
📄 medicine

Real-World Clinical Utility of Genome Sequencing Following the National Expansion of the Rare Disease Diagnostic Support Infrastructure in Korea

The nationwide expansion of Korea's government-led Rare Disease Diagnostic Support Program (KR-RDSP) from 2023 to 2025 demonstrated the clinical utility, scalability, and efficiency of a centralized genome sequencing model, achieving a 35% diagnostic yield and significantly reducing turnaround times to establish genome sequencing as a primary tool for equitable rare disease management.

Seokhui Jang, Seung Hwan Oh, Go Hun Seo, Jinhong Shin, Jee Young Kim, Seonghee Yoon, Ye Eun Lee, Hoon Kook, Dae Hyun Jan (…)2026-10-23
📄 medicine

Outcome Differences in Robotic vs Traditional Total Knee Arthroplasty

A retrospective analysis of 2022–2024 data using the National Surgical Quality Improvement Program database indicates that robotic-assisted total knee arthroplasty, despite requiring longer operation times, results in lower complication and readmission rates, shorter hospital stays, and ultimately reduced overall hospital costs compared to traditional procedures.

Saloni Haruray, Aaron Marcel, Richard Feinn, Karen Myric2026-10-23
📄 medicine

Emergence of Staphylococcus haemolyticus bloodstream infections in a neonatal intensive care unit: six-year evolution of infection prevention and control strategies

This six-year study of a French neonatal intensive care unit reveals the persistent emergence of multidrug-resistant *Staphylococcus haemolyticus* ST29 bloodstream infections despite the progressive implementation of a structured, multidisciplinary infection prevention and control strategy, highlighting the ongoing complexity of managing established resistant pathogens in high-risk settings.

E. Böhme, N. Mazille, B. Youenou, A. Tristan, A. Beuchee, G. Ménard2026-10-23
📄 medicine

Longitudinal Pulmonary Function Progression and Risk of New-Onset Airflow Obstruction in SAD and PRISm: a Multi-Center Population-Based Cohort Study in Southwest China

This multi-center population-based cohort study in Southwest China demonstrates that small-airway dysfunction (SAD) and preserved-ratio impaired spirometry (PRISm), particularly when co-occurring, are significant independent predictors of incident airflow obstruction and distinct longitudinal pulmonary function decline, highlighting their utility as early screening markers despite the need for clinical confirmation.

Yuepeng Li, Chuping Chen, Yi Lei, Rui Zhang, Weimin Li2026-10-23
📄 medicine

Real-World Angiographic and Clinical Outcomes of WEB, Coiling, and Stent-Assisted Coiling for Patients with Unruptured Saccular Intracranial Aneurysms: A Multicenter Study

This multicenter retrospective study from Colombia evaluates the real-world safety and efficacy of stent-assisted coiling, coiling, and WEB devices for unruptured intracranial aneurysms, finding that while stent-assisted coiling showed higher occlusion rates and ischemic complications in the overall cohort, favorable functional outcomes were consistent across all strategies and initial differences were largely attenuated in contemporary analyses, suggesting the results are descriptive rather than definitive evidence of comparative superiority.

Brunno Lara-Coba, C. Alejandro Luzardo-Neira, Camilo Alvarado-Bedoya, Maria F. Estévez-Ochoa, Oscar Eduardo García-Ledes (…)2026-10-23
📄 medicine

Temporal Trends in Survival Among Patients With De Novo Breast Cancer Liver Metastasis, 2010–2023: A Population-Based Cohort Study

This population-based cohort study of over 12,000 patients reveals that while overall survival for those with de novo breast cancer liver metastasis improved between 2010 and 2023, recent gains have plateaued with no significant further progress observed in the 2020–2023 period across any clinical or social subgroups.

Qingliang Jiang, Wen Zhang, Ying Zong, Hengyu Li2026-10-23
📄 medicine

Impact of serial changes of D-dimer in patients with Kawasaki disease: Correlation between the peak D-dimer level and coronary arterial lesions

This study demonstrates that in patients with Kawasaki disease, higher peak D-dimer levels correlate with coronary artery lesions, suggesting that persistently elevated D-dimer levels after IVIG treatment may indicate ongoing vascular involvement and warrant further clinical monitoring.

Kenichi Okumura, Kyosuke Izumi, Takuma Sugawara, Kento Itoi, Kunpei Sekine, Takuzou Wada, Motokazu Nishikado, Yuuko Amim (…)2026-10-23