📄 Category

medicine

6901 papers

📄 medicine

Hand Sanitizer with Sustained Antibacterial and Virucidal Activities Mitigates Upper Respiratory Symptoms and Work Restrictions: Double-blind Household Cluster- randomized Controlled Trial

A double-blind, cluster-randomized controlled trial demonstrated that repeated use of a novel hand sanitizer with sustained antimicrobial activity significantly reduced the incidence of upper respiratory symptoms and work restrictions compared to a conventional ethanol-based sanitizer over a 72-day winter period.

Nami Yamanaka, Kaori Mizukoshi, Kentaro Asaoka, Toshiya Morikawa, Yu Nakashima, Atsuko Hayase2026-06-28
📄 medicine

Prevalence and determinants of tuberculosis-diabetes comorbidity in the Democratic Republic of Congo: a multi-provincial cross-sectional study

This multi-provincial cross-sectional study in the Democratic Republic of Congo reveals that nearly 19% of tuberculosis patients have undiagnosed hyperglycemia, with age, specific geographic locations, family history, hypertension, comorbidities, and multidrug-resistant tuberculosis identified as key independent determinants, thereby supporting the integration of systematic diabetes screening into TB programs.

Lukanu Ngwala Philippe, Likwela Losimba Joris, Tshibungu Ntumba Jeanne, Shoma Matota Mamie, Kufundu Kilonda Isabelle, Ns (…)2026-06-28
📄 medicine

Impact of Initial Therapy and Treatment Interval on Survival in Hepatocellular Carcinoma by Tumor Stage and Child–Pugh Class: Korean Primary Liver Cancer Registry Analysis

Analysis of the Korean Primary Liver Cancer Registry reveals that initial curative-intent therapies are associated with longer intervals before subsequent treatment and independently predict improved overall survival in hepatocellular carcinoma patients across various tumor stages and liver function classes.

Woo Sun Rou, Hyuk Soo Eun, In Sun Kwon, Hong Jae Jeon, Jong Seok Joo, Ju Seok Kim, Eaum Seok Lee, Seok Hyun Kim, Byung S (…)2026-06-28
📄 medicine

Quantitative Assessment of Regional Aerosol Deposition and Early Airway Clearance Using [18F]NaF Nebulized Inhalation PET/CT

This prospective study demonstrates that aerosolized [18F]NaF PET/CT effectively quantifies significantly reduced regional deposition and mucociliary-dominant early clearance in bronchiectatic lungs compared to healthy tissue, establishing 0 minutes as the optimal time point for assessing aerosol delivery.

Xinlu Zhang, Ruiyue Zhao, Shaoyu Liu, Yu Wang, Ziqi Zhang, Shaonan Zhong, Xiang Yan, Zeguang Zheng, Nanshan Zhong, Linli (…)2026-06-28
📄 medicine

Knowledge, attitude, and practice (KAP)-based health education programme for parents of adolescent fixed orthodontic patients: a mixed-methods randomized controlled trial

This mixed-methods randomized controlled trial demonstrates that a Knowledge, Attitude, and Practice (KAP)-based health education programme for parents of adolescents with fixed orthodontic appliances significantly improves parental health literacy, enhances adolescent treatment compliance, and optimizes periodontal outcomes compared to routine care.

Xiaona Sui, Wei Zhang, Sheng Zhai, Jiale Zhu, Xin Liu2026-06-28
📄 medicine

Development and External Validation of a 72-Hour Dynamic Trajectory-Based Machine Learning Model for Mortality Prediction in ICU Patients with Sepsis and Pre-Existing Hypertension

This study developed and externally validated a 72-hour landmark XGBoost model integrating static and dynamic clinical features that outperformed conventional severity scores in predicting in-hospital mortality for ICU patients with sepsis and pre-existing hypertension.

Yufeng Chen¹, Yuan Tian, Hongyang Bian, Wenqing Sun, Xueyan Zhang, Jingjing Zhang¹2026-06-28
📄 medicine

Association between non-HDL cholesterol/HDL cholesterol ratio and new-onset type 2 diabetes: a causal mediation analysis of hs-CRP in the China Health and Retirement Longitudinal Study

In a prospective cohort study of 7,137 Chinese adults aged 45 and older, a higher non-HDL to HDL cholesterol ratio was found to be independently associated with an increased risk of new-onset type 2 diabetes, an association that was not significantly mediated by systemic inflammation as measured by hs-CRP.

Liwei Liu, Zhexue Ren, xuemei jiang, wei deng, yikuan chen2026-06-28
📄 medicine

Unsupervised phenotyping of orofacial function and oral dryness for the identification of dysphagia-risk–enriched profiles in community-dwelling older adults

This study utilized unsupervised clustering of ten oral biomarkers in 200 community-dwelling older adults to identify a reproducible dysphagia-risk-enriched phenotype characterized by lower orofacial function and greater dryness, which showed significant associations with elevated dysphagia screening scores and aspiration risk.

Ji-Su Park, Ga-Yeon Lim, Moon-Young Chang, Gihyoun Lee2026-06-28
📄 medicine

A nomogram prediction model for ovarian endometrioma in patients with endometriosis: a retrospective study based on clinical indicators

This retrospective study developed and validated a high-accuracy nomogram model incorporating history of dysmenorrhea, infertility, fibrinogen levels, and lymphocyte count to effectively predict the risk of ovarian endometrioma in patients with endometriosis, thereby facilitating early identification and stratified clinical management.

Li Shan, Lin Zhong, Li Weihong, Meng Fengyun, Bai Rui, Tang Zhenyu, Guo Pei, Huang Junming, Huang Shuping, Xie Ganzhen2026-06-28