📄 Category

medicine

6901 papers

📄 medicine

Fibrotic Abdominal Tuberculosis Presenting as Acute Small Bowel Obstruction Due to Multiple Bands in a Virgin Abdomen: case report

This case report highlights fibrotic abdominal tuberculosis as a rare but critical cause of small bowel obstruction in a "virgin abdomen," emphasizing the importance of considering this diagnosis in endemic regions despite misleading radiological findings and the necessity of surgical intervention combined with anti-tubercular therapy for favorable outcomes.

Hussam Mohamed Hassan Ibrahim, Waleed M. A. Jebreel, Mohamed Ezeldin Elazz Ibrahim, Ibrahim Mohammed Abbakker Mohammed (…)2026-06-28
📄 medicine

Gambling related harm among active electronic gaming machine players within a social determinants of health framework

This qualitative study of twelve regular electronic gaming machine users in New Zealand reveals that gambling-related harm is sustained by a complex interplay of structural, environmental, and psychological factors, underscoring the need for population-level public health strategies that address commercial and social determinants rather than relying solely on individual-focused harm minimization.

Retina Rimal, Robin-Marie Shepherd, Louise Elizabeth Curley, Frederick Sundram2026-06-28
📄 medicine

SHAP-interpretable machine learning model for early prediction of periventricular leukomalacia in preterm infants younger than 32 weeks: a multicenter validation study

This multicenter validation study developed and validated a highly accurate, SHAP-interpretable Random Forest machine learning model using early clinical data to predict periventricular leukomalacia in preterm infants under 32 weeks gestation, achieving an AUC of 0.930 to facilitate early screening and targeted interventions.

Jiao Yuan, Lingling Xie, Luran Wang, Cuihong Yang, Jie Gu, Yu Wang, Yaoda Wang, Naiying Miao, Huiyu Yang, Yanting Song (…)2026-06-28
📄 medicine

Pre-hospital and Health-System Factors Associated with Emergency Department Disposition Among EMS-Transported Stroke Patients : A Nationwide Thai Cohort

This nationwide Thai cohort study of over 126,000 EMS-transported stroke patients identifies pre-hospital level of consciousness and blood pressure as the strongest predictors of emergency department outcomes, while highlighting significant regional disparities and higher mortality among uninsured and advanced life support-dispatched patients to underscore the need for equity-oriented EMS reforms.

Naruenet Linla, Kittipong Sornlorm, Wongsa Laohasiriwong, Krissana Aunthakot, Phichet Nongchang, Thongsakchai Saiphraraj (…)2026-06-28
📄 medicine

Epidemiology and antimicrobial resistance patterns of neonatal sepsis in a tertiary NICU in Western Ukraine: a 2023–2025 retrospective surveillance study

This 2023–2025 retrospective study of a tertiary NICU in Western Ukraine reveals that neonatal sepsis is predominantly caused by multidrug-resistant organisms, with a notable prevalence of coagulase-negative staphylococci and an increasing burden of resistant Gram-negative pathogens that significantly complicates treatment and contributes to mortality.

Olena Koloskova, Larysa Koliubakina, Ksenia Rudan, Olena Vlasova, Kateryna Vlasova, Victoria Khilchevska2026-06-28
📄 medicine

Impact of Flipped Classroom Combined with Mini-CEX Formative Assessment on Core Competencies in Undergraduate Endocrinology Education: A Randomized Controlled Trial

This randomized controlled trial demonstrates that integrating a flipped classroom with Mini-CEX formative assessment significantly improves theoretical knowledge, clinical skills, self-directed learning, and critical thinking in undergraduate endocrinology education, despite resulting in a higher perceived study workload.

Langen Zhuang, Qianmin Ma, Shengqun Jiang, Xiaoyan Pei, Guoxi Jin, Qiong Xu2026-06-28
📄 medicine

Formulation and Evaluation of Tioconazole Liposomal Gel for Enhanced Topical Antifungal Activity

This study demonstrates that a tioconazole-loaded liposomal gel formulated with soy lecithin and cholesterol significantly enhances skin penetration, prolongs drug release, and improves antifungal efficacy against *Candida albicans* compared to traditional formulations, offering a promising therapeutic strategy for superficial fungal infections.

Arti Ingole, Hitanshi Darji, Ashwini Pansare, P.N. Sable2026-06-28
📄 medicine

Magnitude of uncontrolled type 2 diabetes and associated factors among adults attending Adama Hospital Medical College, Ethiopia

A facility-based cross-sectional study at Adama Hospital Medical College in Ethiopia found a high prevalence of uncontrolled type 2 diabetes (82.9%) among adults, which was significantly associated with factors including khat chewing, alcohol consumption, female gender, specific occupational statuses, and low intake of barley-based foods.

Haji Aman Deybasso, Abebe Megerso Adilo, Endashaw Abebe, Dejene Gemechu, Nura Gudeta2026-06-28
📄 medicine

Dose-Response Impact of Micropapillary Burden on Survival and Its Clinical Interaction with Surgical Extent in Lung Adenocarcinoma: A Propensity Score-Matched Competing Risks Analysis

In patients with lung adenocarcinoma containing micropapillary components, both higher micropapillary burden and sublobar resection independently predict worse survival and recurrence without a significant interaction between them, indicating that lobectomy should be preferred over sublobar resection regardless of micropapillary grade while aggressive adjuvant therapy is warranted for those with >40% micropapillary components.

Liang Zhou, Haitao Liu, junjie zhao, Fan Yang, Weibo Qi, Niu Niu2026-06-28
📄 medicine

Patient-specific antibiotic susceptibility ranking for empirical treatment of gram-negative bloodstream infection: a retrospective clinical decision-support and transportability study

This retrospective study demonstrates that a patient-specific antibiotic susceptibility ranking model significantly improves empirical active coverage for gram-negative bloodstream infections compared to clinician prescribing, primarily by recommending meropenem, though its external transportability is limited to drug-specific predictions rather than direct policy transfer.

Xiao Liu, Le Han, Wei Wang, Peng Xian, Yue Chang, Ying Liu, Lijun Ma, Jie Ren, Yunshuang Liu, Xiaosong Wang, Yujuan Long (…)2026-06-28