6901 papers
This economic evaluation demonstrates that while Sacituzumab tirumotecan is marginally cost-effective for EGFR-TKI–resistant NSCLC patients within the Chinese healthcare system, it is not cost-effective for U.S. patients under current pricing, necessitating significant price reductions to meet American willingness-to-pay thresholds.
This study demonstrates that while both portal phase CT values and the difference between portal and delayed phase CT values (ΔCT) effectively predict the biological activity of cystic hepatic echinococcosis, ΔCT values offer superior diagnostic efficacy in evaluating cyst inactivation and guiding clinical decisions.
This case-control study conducted in Iraq demonstrates that newly diagnosed children with ADHD have significantly lower serum ferritin and zinc levels compared to healthy controls, with these deficiencies being strongly correlated with symptom severity and specific ADHD subtypes.
This pilot study demonstrates that integrating the CAARISMA®ARMM AI algorithm with Vectra® imaging provides a novel, objective, and reproducible method for assessing significant improvements in facial youth, attractiveness, and skin quality following combined facial aesthetic surgery, thereby reducing observer bias in outcome evaluation.
This cross-sectional study of 392 undergraduate students in Kano, Nigeria, reveals a high prevalence of perceived stress (77.5%) primarily managed through adaptive coping strategies, where personality traits like neuroticism and extraversion significantly predict specific coping styles but not stress levels themselves, while age, sex, and academic level serve as key predictors of stress burden.
This cross-sectional study of 505 terminally ill older adults and their family members in China reveals significant discrepancies in end-of-life treatment preferences and decision-making roles, highlighting the need for enhanced advance care planning and communication to ensure patient wishes are accurately represented.
This paper presents the Explanation and Elaboration document for the STROBE-MetEpi checklist, a new reporting guideline designed to enhance the transparency, completeness, and reproducibility of observational metabolomic epidemiology studies by providing detailed rationale and examples for each of its 31 items.
This study demonstrates that CADM1 expression is significantly upregulated in the colonic mucosa of ulcerative colitis patients, where it correlates positively with disease severity, p-STAT3 activation, and CD11c-positive cell infiltration, suggesting its potential as a tissue marker for mucosal inflammation and immune microenvironment changes.
This cross-sectional study of 791 Slovak postpartum women reveals that clinically significant pelvic girdle pain affects approximately 21.7% of the population and is strongly associated with increased pelvic floor discomfort and back pain-related disability, highlighting the need for integrated multidisciplinary care.
This retrospective study comparing non-cardiac-origin cardiac arrest patients in Slovenia between 2010/2011 and 2022/2023 found that while the proportion of out-of-hospital events and bystander CPR increased alongside more intensive management, overall survival and neurological outcomes remained unchanged despite improved survival rates specifically for in-hospital arrests.